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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1951 3
1952 1
1953 1
1955 1
1956 1
1957 2
1958 3
1959 1
1960 2
1961 3
1962 6
1963 14
1964 38
1965 46
1966 55
1967 73
1968 129
1969 156
1970 154
1971 268
1972 290
1973 247
1974 273
1975 232
1976 211
1977 230
1978 276
1979 359
1980 435
1981 503
1982 628
1983 753
1984 891
1985 991
1986 1158
1987 1372
1988 1613
1989 2103
1990 2479
1991 2911
1992 3161
1993 3694
1994 3990
1995 4390
1996 4551
1997 4837
1998 5183
1999 5483
2000 6156
2001 6816
2002 6781
2003 7305
2004 7784
2005 8498
2006 9202
2007 9572
2008 10288
2009 10772
2010 11046
2011 11668
2012 11642
2013 11742
2014 11479
2015 11279
2016 11065
2017 11290
2018 11120
2019 10838
2020 10343
2021 9189
2022 6688
2023 5402
2024 5531
2025 7

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263,831 results

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Page 1
Biology and evolution of bacterial toxin-antitoxin systems.
Jurėnas D, Fraikin N, Goormaghtigh F, Van Melderen L. Jurėnas D, et al. Nat Rev Microbiol. 2022 Jun;20(6):335-350. doi: 10.1038/s41579-021-00661-1. Epub 2022 Jan 2. Nat Rev Microbiol. 2022. PMID: 34975154 Review.
Toxin-antitoxin systems are widespread in bacterial genomes. They are usually composed of two elements: a toxin that inhibits an essential cellular process and an antitoxin that counteracts its cognate toxin. ...However, recent advances in the field profoundly questioned t …
Toxin-antitoxin systems are widespread in bacterial genomes. They are usually composed of two elements: a toxin that inhibits an esse …
Discovery of bioactive microbial gene products in inflammatory bowel disease.
Zhang Y, Bhosle A, Bae S, McIver LJ, Pishchany G, Accorsi EK, Thompson KN, Arze C, Wang Y, Subramanian A, Kearney SM, Pawluk A, Plichta DR, Rahnavard A, Shafquat A, Xavier RJ, Vlamakis H, Garrett WS, Krueger A, Huttenhower C, Franzosa EA. Zhang Y, et al. Nature. 2022 Jun;606(7915):754-760. doi: 10.1038/s41586-022-04648-7. Epub 2022 May 25. Nature. 2022. PMID: 35614211 Free PMC article.
However, even in well-characterized environments (for example, the human gastrointestinal tract), more than one-third of microbial proteins are uncharacterized and often expected to be bioactive(5-7). Here we systematically identified more than 340,000 protein families as …
However, even in well-characterized environments (for example, the human gastrointestinal tract), more than one-third of microbial protei …
Genomics and Genetics of Streptococcus pneumoniae.
Santoro F, Iannelli F, Pozzi G. Santoro F, et al. Microbiol Spectr. 2019 May;7(3):10.1128/microbiolspec.gpp3-0025-2018. doi: 10.1128/microbiolspec.GPP3-0025-2018. Microbiol Spectr. 2019. PMID: 31111814 Free PMC article. Review.
Ninety years after the discovery of pneumococcal Transformation, and 74 years after the work of Avery and colleagues that identified DNA as the genetic material, Streptococcus pneumoniae is still one of the most important model organism to understand Bacterial Ge …
Ninety years after the discovery of pneumococcal Transformation, and 74 years after the work of Avery and colleagues that identified DNA as …
Arming the troops: Post-translational modification of extracellular bacterial proteins.
Forrest S, Welch M. Forrest S, et al. Sci Prog. 2020 Oct-Dec;103(4):36850420964317. doi: 10.1177/0036850420964317. Sci Prog. 2020. PMID: 33148128 Free PMC article. Review.
Protein secretion is almost universally employed by bacteria. Some proteins are retained on the cell surface, whereas others are released into the extracellular milieu, often playing a key role in virulence. In this review, we discuss the diverse types and potential functi …
Protein secretion is almost universally employed by bacteria. Some proteins are retained on the cell surface, whereas others are rele …
Editorial overview: Bacterial systems biology.
Dehio C, Bumann D. Dehio C, et al. Curr Opin Microbiol. 2017 Oct;39:viii-xi. doi: 10.1016/j.mib.2017.11.024. Curr Opin Microbiol. 2017. PMID: 29241558 No abstract available.
Bdellovibrio bacteriovorus uses chimeric fibre proteins to recognize and invade a broad range of bacterial hosts.
Caulton SG, Lambert C, Tyson J, Radford P, Al-Bayati A, Greenwood S, Banks EJ, Clark C, Till R, Pires E, Sockett RE, Lovering AL. Caulton SG, et al. Nat Microbiol. 2024 Jan;9(1):214-227. doi: 10.1038/s41564-023-01552-2. Epub 2024 Jan 4. Nat Microbiol. 2024. PMID: 38177296 Free PMC article.
The mechanisms underlying prey recognition and handling remain obscure. Here we use complementary genetic, microscopic and structural methods to address this deficit. ...These dynamic proteins indicate a variety of binding capabilities, and we confirm that one MAT m …
The mechanisms underlying prey recognition and handling remain obscure. Here we use complementary genetic, microscopic and structural …
Microbial proteomics: the quiet revolution.
Séraphin B, Hettich R. Séraphin B, et al. Curr Opin Microbiol. 2012 Jun;15(3):348-50. doi: 10.1016/j.mib.2012.05.004. Epub 2012 May 23. Curr Opin Microbiol. 2012. PMID: 22632759 No abstract available.
Metagenome Driven Discovery of Nonribosomal Peptides.
Stevenson LJ, Owen JG, Ackerley DF. Stevenson LJ, et al. ACS Chem Biol. 2019 Oct 18;14(10):2115-2126. doi: 10.1021/acschembio.9b00618. Epub 2019 Sep 20. ACS Chem Biol. 2019. PMID: 31508935 Review.
The nonribosomal peptides have received particular focus, owing to their high levels of bioactivity and the predictability of the biosynthetic logic of the genetically encoded assembly lines that produce them. By uniting advances in next-generation sequencing and bioinform …
The nonribosomal peptides have received particular focus, owing to their high levels of bioactivity and the predictability of the biosynthet …
Shotgun proteomics of bacterial pathogens: advances, challenges and clinical implications.
Semanjski M, Macek B. Semanjski M, et al. Expert Rev Proteomics. 2016;13(2):139-56. doi: 10.1586/14789450.2016.1132168. Epub 2016 Jan 11. Expert Rev Proteomics. 2016. PMID: 26653908 Review.
Mass spectrometry-based proteomics is increasingly used in analysis of bacterial pathogens. Simple experimental set-ups based on high accuracy mass spectrometry and powerful biochemical and bioinformatics tools are capable of reliably quantifying levels of several thousand …
Mass spectrometry-based proteomics is increasingly used in analysis of bacterial pathogens. Simple experimental set-ups based on high …
Bacterial glycoproteomics.
Hitchen PG, Dell A. Hitchen PG, et al. Microbiology (Reading). 2006 Jun;152(Pt 6):1575-1580. doi: 10.1099/mic.0.28859-0. Microbiology (Reading). 2006. PMID: 16735721 Free article. Review.
Glycosylated proteins are ubiquitous components of eukaryote cellular surfaces, where the glycan moieties are implicated in a wide range of cell-cell recognition events. ...This review highlights the capabilities of high-sensitivity mass spectrometry for carbohydrate struc …
Glycosylated proteins are ubiquitous components of eukaryote cellular surfaces, where the glycan moieties are implicated in a wide ra …
263,831 results
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