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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1993 1
1997 1
1998 2
1999 2
2000 7
2001 5
2002 4
2003 6
2004 12
2005 10
2006 6
2007 9
2008 10
2009 14
2010 14
2011 14
2012 21
2013 27
2014 18
2015 21
2016 19
2017 24
2018 20
2019 23
2020 21
2021 24
2022 22
2023 20
2024 19
2025 13
2026 10

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388 results

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Page 1
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.
Harrington LB, Burstein D, Chen JS, Paez-Espino D, Ma E, Witte IP, Cofsky JC, Kyrpides NC, Banfield JF, Doudna JA. Harrington LB, et al. Science. 2018 Nov 16;362(6416):839-842. doi: 10.1126/science.aav4294. Epub 2018 Oct 18. Science. 2018. PMID: 30337455 Free PMC article.
CRISPR-CasΦ from huge phages is a hypercompact genome editor.
Pausch P, Al-Shayeb B, Bisom-Rapp E, Tsuchida CA, Li Z, Cress BF, Knott GJ, Jacobsen SE, Banfield JF, Doudna JA. Pausch P, et al. Science. 2020 Jul 17;369(6501):333-337. doi: 10.1126/science.abb1400. Science. 2020. PMID: 32675376 Free PMC article.
A new view of the tree of life.
Hug LA, Baker BJ, Anantharaman K, Brown CT, Probst AJ, Castelle CJ, Butterfield CN, Hernsdorf AW, Amano Y, Ise K, Suzuki Y, Dudek N, Relman DA, Finstad KM, Amundson R, Thomas BC, Banfield JF. Hug LA, et al. Nat Microbiol. 2016 Apr 11;1:16048. doi: 10.1038/nmicrobiol.2016.48. Nat Microbiol. 2016. PMID: 27572647 Free article.
Structure and evolution-guided design of minimal RNA-guided nucleases.
Skopintsev P, Esain-Garcia I, DeTurk EC, Yoon PH, Zhou Z, Weiss T, Kamalu M, Chamraj A, Loi KJ, Langeberg CJ, Boger R, Nisonoff H, Karp HM, Chen L, Shi H, Vohra K, Banfield JF, Cate JHD, Jacobsen SE, Doudna JA. Skopintsev P, et al. bioRxiv [Preprint]. 2025 Dec 8:2025.12.08.692503. doi: 10.64898/2025.12.08.692503. bioRxiv. 2025. Update in: Science. 2026 Jul 16;393(6808):313-318. doi: 10.1126/science.aed6123. PMID: 41573840 Free PMC article. Updated. Preprint.
Structure and evolution-guided design of minimal RNA-guided nucleases.
Skopintsev P, Esain-Garcia I, DeTurk EC, Yoon PH, Zhou Z, Weiss T, Kamalu M, Chamraj A, Loi KJ, Langeberg CJ, Boger RS, Nisonoff H, Karp HM, Chen LX, Shi H, Vohra K, Banfield JF, Cate JHD, Jacobsen SE, Doudna JA. Skopintsev P, et al. Science. 2026 Jul 16;393(6808):313-318. doi: 10.1126/science.aed6123. Epub 2026 Jul 16. Science. 2026. PMID: 42462008 Free PMC article.
Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Al-Shayeb B, Skopintsev P, Soczek KM, Stahl EC, Li Z, Groover E, Smock D, Eggers AR, Pausch P, Cress BF, Huang CJ, Staskawicz B, Savage DF, Jacobsen SE, Banfield JF, Doudna JA. Al-Shayeb B, et al. Cell. 2022 Nov 23;185(24):4574-4586.e16. doi: 10.1016/j.cell.2022.10.020. Cell. 2022. PMID: 36423580 Free article.
The NIH Somatic Cell Genome Editing program.
Saha K, Sontheimer EJ, Brooks PJ, Dwinell MR, Gersbach CA, Liu DR, Murray SA, Tsai SQ, Wilson RC, Anderson DG, Asokan A, Banfield JF, Bankiewicz KS, Bao G, Bulte JWM, Bursac N, Campbell JM, Carlson DF, Chaikof EL, Chen ZY, Cheng RH, Clark KJ, Curiel DT, Dahlman JE, Deverman BE, Dickinson ME, Doudna JA, Ekker SC, Emborg ME, Feng G, Freedman BS, Gamm DM, Gao G, Ghiran IC, Glazer PM, Gong S, Heaney JD, Hennebold JD, Hinson JT, Khvorova A, Kiani S, Lagor WR, Lam KS, Leong KW, Levine JE, Lewis JA, Lutz CM, Ly DH, Maragh S, McCray PB Jr, McDevitt TC, Mirochnitchenko O, Morizane R, Murthy N, Prather RS, Ronald JA, Roy S, Roy S, Sabbisetti V, Saltzman WM, Santangelo PJ, Segal DJ, Shimoyama M, Skala MC, Tarantal AF, Tilton JC, Truskey GA, Vandsburger M, Watts JK, Wells KD, Wolfe SA, Xu Q, Xue W, Yi G, Zhou J; SCGE Consortium. Saha K, et al. Nature. 2021 Apr;592(7853):195-204. doi: 10.1038/s41586-021-03191-1. Epub 2021 Apr 7. Nature. 2021. PMID: 33828315 Free PMC article. Review.
Candidate Phyla Radiation bacteria.
Jaffe AL, Banfield JF. Jaffe AL, et al. Curr Biol. 2024 Feb 5;34(3):R80-R81. doi: 10.1016/j.cub.2023.12.024. Curr Biol. 2024. PMID: 38320475 Free article.
Accurate and complete genomes from metagenomes.
Chen LX, Anantharaman K, Shaiber A, Eren AM, Banfield JF. Chen LX, et al. Genome Res. 2020 Mar;30(3):315-333. doi: 10.1101/gr.258640.119. Epub 2020 Mar 18. Genome Res. 2020. PMID: 32188701 Free PMC article. Review.
388 results