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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 6
1996 13
1997 24
1998 29
1999 32
2000 37
2001 60
2002 54
2003 54
2004 56
2005 43
2006 29
2007 27
2008 21
2009 18
2010 18
2011 17
2012 19
2013 14
2014 15
2015 16
2016 13
2017 8
2018 5
2019 1
2020 0
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575 results
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Page 1
The role of the exogenous supply of adenosine triphosphate in the expression of Bax and Bcl2L1 genes in intestinal ischemia and reperfusion in rats 1.
Fagundes DJ, et al. Acta Cir Bras 2018. PMID 30484498 Free article.
Afterwards, intestinal segments were appropriately removed and processed for Endothelial Cell Biology Rat RT2 Profiler PCR Array. ...CONCLUSION: Adenosine triphosphate was associated with antiapoptotic effects on the rat intestine ischemia and reperfusion by upregulating of Bcl2L1 gene expression....
Afterwards, intestinal segments were appropriately removed and processed for Endothelial Cell Biology Rat RT2 Profiler PCR Array. ... …
rno-miR-665 targets BCL2L1 (Bcl-xl) and increases vulnerability to propofol in developing astrocytes.
Sun WC and Pei L. J Neurochem 2016. PMID 27121046 Free article.
In addition, the utility of A-1155463, a highly potent and BCL2L1-selective antagonist, was aimed to assess the contribution of BCL2L1 for neuroglial survival. ...Combination treatment with A-1155463 and propofol induced lower mRNA and protein levels of BCL2L1 and more CC3 activation than propofol treatment alone in vivo. ...
In addition, the utility of A-1155463, a highly potent and BCL2L1-selective antagonist, was aimed to assess the contribution of BC
Oxidative stress-induced apoptotic insults to rat osteoblasts are attenuated by nitric oxide pretreatment via GATA-5-involved regulation of Bcl-X L gene expression and protein translocation.
Wu GJ, et al. Arch Toxicol 2016. PMID 25726415
In contrast, pretreatment with NO enhanced levels and translocation of antiapoptotic Bcl-XL protein in rat osteoblasts. RNA analyses further revealed that HP inhibited Bcl-XL mRNA expression without affecting Bax mRNA levels. ...As to the mechanism, HP suppressed RNA and protein levels of transcription factor GATA-5 in rat osteoblasts. Pretreatment with NO induced GATA-5 mRNA and protein expressions and simultaneously attenuated HP-induced inhibition of this gene's expression. ...
In contrast, pretreatment with NO enhanced levels and translocation of antiapoptotic Bcl-XL protein in rat osteoblasts. RNA an …
Mild hypothermia enhanced the protective effect of protein therapy with transductive anti-death FNK protein using a rat focal transient cerebral ischemia model.
Sakurazawa M, et al. Brain Res 2012. PMID 22099262
We previously reported that the protein transduction domain fused FNK (PTD-FNK) protein, which was derived from anti-apoptotic Bcl-xL protein and thereby gained higher anti-cell death activity, has a strong neuroprotective effect on rat focal brain ischemia models. The aim of this study was to investigate the effect of PTD-FNK protein and hypothermia combined therapy on cerebral infarction. ...
We previously reported that the protein transduction domain fused FNK (PTD-FNK) protein, which was derived from anti-apoptotic …
Characterization of urocortin as an anti-apoptotic protein in experimental ischemia-reperfusion model of the rat testis.
Sumii K, et al. Biochem Biophys Res Commun 2016. PMID 27659706
The objective of this study was to investigate the role of urocortin in testicular apoptosis using an experimental ischemia-reperfusion rat model. ...These findings suggest that urocortin may play a cytoprotective role in the germ cells in response to ischemia-reperfusion injury through the activation of major anti-apoptotic proteins, as well as by the mitogen-activated protein kinase signaling pathway activation....
The objective of this study was to investigate the role of urocortin in testicular apoptosis using an experimental ischemia-reperfusion r
Gonadotropin-Dependent Neuregulin-1 Signaling Regulates Female Rat Ovarian Granulosa Cell Survival.
Chowdhury I, et al. Endocrinology 2017. PMID 28938399 Free PMC article.
During the estrous cycle of rat, NRG1 and erbB receptors are differentially expressed in GCs and correlate positively with serum gonadotropins and steroid hormones. Moreover, in vitro experimental studies suggest that the protein kinase C inhibitor staurosporine (STS) causes the physical destruction of GCs by the activation of caspase-3. ...
During the estrous cycle of rat, NRG1 and erbB receptors are differentially expressed in GCs and correlate positively with serum gona …
Optogenetic Stimulation Increases Level of Antiapoptotic Protein Bcl-xL in Neurons.
Lanshakov DA, et al. Biochemistry (Mosc) 2017. PMID 28320275 Free article.
Increase in the level of early response c-Fos protein following illumination with blue light was indicative of activation of these hippocampal neurons. ...The dependence of the level of expression of Bcl-xL protein on the activity of neurons indicates that this protein possesses one more important property that is essential for participation in neuroplastic processes in the brain....
Increase in the level of early response c-Fos protein following illumination with blue light was indicative of activation of these hi …
Propofol-induced rno-miR-665 targets BCL2L1 and influences apoptosis in rodent developing hippocampal astrocytes.
Sun WC, et al. Neurotoxicology 2015. PMID 26254736
Bioinformatics predicted putative binding sites for rno-miR-665 existing in the 3'-untranslated region of Bcl-2-like protein 1 BCL2L1 (Bcl-xl) mRNA. ...Taken together, rno-miR-665 is involved in the neurotoxicity induced by propofol via a caspase-3 mediated mechanism by negatively regulating BCL2L1. ...
Bioinformatics predicted putative binding sites for rno-miR-665 existing in the 3'-untranslated region of Bcl-2-like protein 1 BCL
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