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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1966 1
1969 1
1973 2
1974 3
1975 7
1976 7
1977 9
1978 8
1979 7
1980 6
1981 15
1982 15
1983 16
1984 22
1985 33
1986 29
1987 37
1988 68
1989 102
1990 136
1991 154
1992 260
1993 348
1994 416
1995 424
1996 512
1997 570
1998 561
1999 636
2000 770
2001 815
2002 942
2003 1094
2004 1654
2005 1474
2006 1733
2007 1890
2008 2074
2009 2304
2010 2639
2011 3022
2012 3513
2013 3700
2014 3843
2015 4126
2016 4250
2017 4594
2018 4696
2019 5111
2020 5637
2021 6158
2022 6085
2023 6044
2024 6058
2025 72

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77,574 results

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Page 1
Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer's disease and mild cognitive impairment.
Chandra A, Valkimadi PE, Pagano G, Cousins O, Dervenoulas G, Politis M; Alzheimer's Disease Neuroimaging Initiative. Chandra A, et al. Hum Brain Mapp. 2019 Dec 15;40(18):5424-5442. doi: 10.1002/hbm.24782. Epub 2019 Sep 14. Hum Brain Mapp. 2019. PMID: 31520513 Free PMC article. Review.
Alzheimer's disease (AD) is a devastating and progressive neurodegenerative disease for which there is no cure. Mild cognitive impairment (MCI) is considered a prodromal stage of the disease. Molecular imaging with positron emission tomography (PET) allows fo …
Alzheimer's disease (AD) is a devastating and progressive neurodegenerative disease for which there is no cure. Mild cognitive …
SPECT and PET imaging in Alzheimer's disease.
Valotassiou V, Malamitsi J, Papatriantafyllou J, Dardiotis E, Tsougos I, Psimadas D, Alexiou S, Hadjigeorgiou G, Georgoulias P. Valotassiou V, et al. Ann Nucl Med. 2018 Nov;32(9):583-593. doi: 10.1007/s12149-018-1292-6. Epub 2018 Aug 20. Ann Nucl Med. 2018. PMID: 30128693 Review.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Beta-amyloid (Abeta) deposition and neurofibrillary tangles (NFTs) of abnormal hyperphosphorylated tau protein are the pathological hallmarks of the disease, …
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Beta-amyloid (Abet …
Piramal Imaging.
Dinkelborg L. Dinkelborg L. Neurodegener Dis Manag. 2015 Aug;5(4):283-8. doi: 10.2217/nmt.15.26. Epub 2015 Aug 21. Neurodegener Dis Manag. 2015. PMID: 26295720
5-(5-(2-(2-(2-[18F]Fluoroethoxy)ethoxy)ethoxy)benzofuran-2-yl)-N-methylpyridin-2-amine.
Leung K. Leung K. 2011 Jun 11 [updated 2011 Sep 1]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2011 Jun 11 [updated 2011 Sep 1]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 21901867 Free Books & Documents. Review.
However, [(18)F]FDDNP showed low signal/noise ratios for PET imaging because it is highly lipophilic. N-Methyl-[(11)C]-2-(4'-methylaminophenyl)-6-hydroxybenzothiasole, a beta-amyloid binding compound based on a series of neutral thioflavin-T derivative …
However, [(18)F]FDDNP showed low signal/noise ratios for PET imaging because it is highly lipophilic. N-Methyl-[(11)C]-2-(4'-m …
2-(4-Aminophenyl)-6-(2-([18F]fluoroethoxy))quinoline.
Leung K. Leung K. 2011 Jun 27 [updated 2011 Sep 29]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2011 Jun 27 [updated 2011 Sep 29]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 21977530 Free Books & Documents. Review.
Of these analogs, 2-(1-(6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl)ethylidene)malono nitrile ([(18)F]FDDNP) has been studied in humans, showing more binding in the brains of patients with AD than in those of healthy people (14). [(18)F]FDDNP has been found to bind to both …
Of these analogs, 2-(1-(6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl)ethylidene)malono nitrile ([(18)F]FDDNP) has been studied in huma …
2-{3-[18F]Fluoro-4-(methylamino)phenyl}-1,3-benzothiazol-6-ol.
Chopra A. Chopra A. 2012 Nov 14 [updated 2012 Dec 27]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Nov 14 [updated 2012 Dec 27]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23285496 Free Books & Documents. Review.
Flutemetamol is a thioflavin T derivative of PIB and bears (18)F-fluorine on the 3' position of the parent molecule (7). The biodistribution and PET imaging of Abeta plaques with [(18)F]flutemetamol have been investigated in rodents (8), healthy human volunteers (5, …
Flutemetamol is a thioflavin T derivative of PIB and bears (18)F-fluorine on the 3' position of the parent molecule (7). The biodistribution …
Predicting Amyloid-beta Levels in Amnestic Mild Cognitive Impairment Using Machine Learning Techniques.
Ezzati A, Harvey DJ, Habeck C, Golzar A, Qureshi IA, Zammit AR, Hyun J, Truelove-Hill M, Hall CB, Davatzikos C, Lipton RB; Alzheimer’s Disease Neuroimaging Initiative. Ezzati A, et al. J Alzheimers Dis. 2020;73(3):1211-1219. doi: 10.3233/JAD-191038. J Alzheimers Dis. 2020. PMID: 31884486 Free PMC article.
Predicting Abeta positivity prior to PET imaging can decrease unnecessary patient burden and costs of running these trials. OBJECTIVE: The aim of this study was to evaluate the performance of a machine learning model in estimating the individual risk of Abeta+ based …
Predicting Abeta positivity prior to PET imaging can decrease unnecessary patient burden and costs of running these trials. OB …
Beta-amyloid imaging with florbetaben.
Sabri O, Seibyl J, Rowe C, Barthel H. Sabri O, et al. Clin Transl Imaging. 2015;3(1):13-26. doi: 10.1007/s40336-015-0102-6. Epub 2015 Feb 12. Clin Transl Imaging. 2015. PMID: 25741488 Free PMC article. Review.
The potential of florbetaben to predict AD dementia in cases of mild cognitive impairment and to assist in the differential diagnosis in cases of dementia is also described. ...Taken together, the evidence shows that florbetaben is a valuable beta-a …
The potential of florbetaben to predict AD dementia in cases of mild cognitive impairment and to assist in the differen …
[(18)F]Florbetaben: a review in beta-amyloid PET imaging in cognitive impairment.
Syed YY, Deeks E. Syed YY, et al. CNS Drugs. 2015 Jul;29(7):605-13. doi: 10.1007/s40263-015-0258-7. CNS Drugs. 2015. PMID: 26175116 Review.
Intravenous (18)F-labelled florbetaben ([(18)F]florbetaben) [Neuraceq] is a polyethylene glycol stilbene derivative that is approved in the USA, EU and South Korea for positron emission tomography (PET) imaging of the brain. It is used to estimate beta-amy …
Intravenous (18)F-labelled florbetaben ([(18)F]florbetaben) [Neuraceq] is a polyethylene glycol stilbene derivative that is approved in the …
Changes in cognition.
Albert MS. Albert MS. Neurobiol Aging. 2011 Dec;32 Suppl 1(0 1):S58-63. doi: 10.1016/j.neurobiolaging.2011.09.010. Neurobiol Aging. 2011. PMID: 22078174 Free PMC article. Review.
This impairment in episodic memory is evident among individuals with mild cognitive impairment (MCI) and can be used to predict likelihood of progression to dementia, particularly in association with AD biomarkers. ...Similarly, there are correlations between …
This impairment in episodic memory is evident among individuals with mild cognitive impairment (MCI) and can be used to …
77,574 results
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