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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 1
1987 8
1988 6
1989 4
1990 10
1991 5
1992 8
1993 7
1994 8
1995 10
1996 7
1997 13
1998 8
1999 8
2000 10
2001 17
2002 7
2003 12
2004 8
2005 16
2006 14
2007 14
2008 14
2009 12
2010 20
2011 18
2012 22
2013 19
2014 18
2015 29
2016 25
2017 26
2018 27
2019 10
2020 0
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413 results
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Page 1
Pathogenesis of biliary atresia: defining biology to understand clinical phenotypes.
Asai A, et al. Nat Rev Gastroenterol Hepatol 2015 - Review. PMID 26008129 Free PMC article.
Biliary atresia is a severe cholangiopathy of early infancy that destroys extrahepatic bile ducts and disrupts bile flow. With a poorly defined disease pathogenesis, treatment consists of the surgical removal of duct remnants followed by hepatoportoenterostomy. ...Stronger evidence exists for viruses, toxins and gene sequence variations in the aetiology of biliary atresia, triggering a proinflammatory response that injures the duct epithelium and produces a rapidly progressive cholangiopathy. ...
Biliary atresia is a severe cholangiopathy of early infancy that destroys extrahepatic bile ducts and disrupts bile flow. With
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia.
Lertudomphonwanit C, et al. Sci Transl Med 2017. PMID 29167395 Free PMC article.
In a discovery cohort of 70 subjects, the lead biomarker was matrix metalloproteinase-7 (MMP-7), which retained high distinguishing features for biliary atresia in two validation cohorts. ...Thus, we propose that serum MMP-7 (alone or in combination with GGT) is a diagnostic biomarker for biliary atresia and may serve as a therapeutic target....
In a discovery cohort of 70 subjects, the lead biomarker was matrix metalloproteinase-7 (MMP-7), which retained high distinguishing features …
Diagnostic Accuracy of Serum Matrix Metalloproteinase-7 for Biliary Atresia.
Yang L, et al. Hepatology 2018 - Clinical Trial. PMID 30153340 Free PMC article.
The diagnosis of biliary atresia (BA) remains a clinical challenge because affected infants have signs, symptoms, and serum liver biochemistry that are also seen in those with other causes of neonatal cholestasis (non-BA). ...
The diagnosis of biliary atresia (BA) remains a clinical challenge because affected infants have signs, symptoms, and serum li …
Clinical Assessment of Differential Diagnostic Methods in Infants with Cholestasis due to Biliary Atresia or Non-Biliary Atresia.
Dong C, et al. Curr Med Sci 2018. PMID 30074163
The different methods in differentiating biliary atresia (BA) from non-BA-related cholestasis were evaluated in order to provide a practical basis for a rapid, early and accurate differential diagnosis of the diseases. 396 infants with cholestatic jaundice were studied prospectively during the period of May 2007 to June 2011. ...
The different methods in differentiating biliary atresia (BA) from non-BA-related cholestasis were evaluated in order to provi …
MULTIVARIATE ANALYSIS OF BILIARY FLOW-RELATED FACTORS AND POST-KASAI SURVIVAL IN BILIARY ATRESIA PATIENTS.
Ferreira AR, et al. Arq Gastroenterol 2019. PMID 31141068 Free article.
BACKGROUND: Biliary atresia represents the most common surgically treatable cause of cholestasis in newborns. If not corrected, secondary biliary cirrhosis invariably results. ...METHODS: The study analyzed data from 117 biliary atresia patients who underwent portoenterostomy and had suitable histological material for evaluation. ...
BACKGROUND: Biliary atresia represents the most common surgically treatable cause of cholestasis in newborns. If not corrected …
Role of CD56-expressing immature biliary epithelial cells in biliary atresia.
Zhang RZ, et al. World J Gastroenterol 2016. PMID 26937142 Free PMC article.
AIM: To analyze the clinical and pathological parameters and expression of the neural cell adhesion molecule (CD56) in patients with biliary atresia (BA). METHODS: Established clinical laboratory markers of hepatic function, including enzyme activity, protein synthesis, and bilirubin metabolism, were evaluated in patients with BA and compared with those in patients with choledochal cysts and neonatal hepatitis. ...
AIM: To analyze the clinical and pathological parameters and expression of the neural cell adhesion molecule (CD56) in patients with bili
Interactions between Th1 cells and Tregs affect regulation of hepatic fibrosis in biliary atresia through the IFN-γ/STAT1 pathway.
Wen J, et al. Cell Death Differ 2017. PMID 28304404 Free PMC article.
Retracted
Regulatory T cells (Tregs) and CD4(+) T helper (Th) cells have important roles in bile duct injury of biliary atresia (BA). However, their impacts on liver fibrosis are undefined. ...
Regulatory T cells (Tregs) and CD4(+) T helper (Th) cells have important roles in bile duct injury of biliary atresia (BA). Ho …
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