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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1952 3
1955 3
1956 3
1957 9
1958 7
1959 13
1960 7
1961 6
1962 7
1964 4
1965 22
1966 37
1967 52
1968 56
1969 48
1970 54
1971 39
1972 42
1973 50
1974 49
1975 58
1976 51
1977 53
1978 72
1979 53
1980 67
1981 85
1982 82
1983 82
1984 100
1985 118
1986 122
1987 148
1988 166
1989 133
1990 131
1991 105
1992 127
1993 127
1994 116
1995 132
1996 170
1997 133
1998 135
1999 158
2000 163
2001 171
2002 188
2003 208
2004 196
2005 213
2006 213
2007 230
2008 250
2009 236
2010 275
2011 314
2012 310
2013 348
2014 409
2015 403
2016 330
2017 333
2018 343
2019 195
2020 4
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8,055 results
Results by year
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Page 1
Peribiliary Glands as the Cellular Origin of Biliary Tract Cancer.
Nakagawa H, et al. Int J Mol Sci 2018 - Review. PMID 29895797 Free PMC article.
Although CCA has been considered to originate from biliary epithelial cells, recent studies have suggested that multiple cell types can develop into CCA. With regard to the hilar and extrahepatic bile ducts, peribiliary glands (PBGs), a potential stem cell niche of biliary epithelial cells, have attracted attention as the cellular origin of biliary tract cancer. ...
Although CCA has been considered to originate from biliary epithelial cells, recent studies have suggested that multiple cell types c …
Extrahepatic Manifestations of Primary Biliary Cholangitis.
Chalifoux SL, et al. Gut Liver 2017 - Review. PMID 28292174 Free PMC article.
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by progressive destruction of the intrahepatic bile ducts, leading to cholestasis. ...Due to the high prevalence of extrahepatic diseases in patients with PBC, it is important to complete a thorough medical history at the time of diagnosis. ...
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by progressive destruction of the intrahepatic bile du …
Molecular pathology of biliary tract cancers.
Fava G, et al. Cancer Lett 2007 - Review. PMID 17069969
The molecular mechanisms underlying the development, growth and metastatic diffusion of biliary tract cancers are still undefined. ...A more complete characterization of the molecular pathology of bile duct cancers could lead to the identification of valid targets for the diagnosis and therapy of these devastating malignancies. ...
The molecular mechanisms underlying the development, growth and metastatic diffusion of biliary tract cancers are still undefi …
Emerging concepts in biliary repair and fibrosis.
Fabris L, et al. Am J Physiol Gastrointest Liver Physiol 2017 - Review. PMID 28526690 Free PMC article.
Chronic diseases of the biliary tree (cholangiopathies) represent one of the major unmet needs in clinical hepatology and a significant knowledge gap in liver pathophysiology. The common theme in cholangiopathies is that the target of the disease is the biliary tree. After damage to the biliary epithelium, inflammatory changes stimulate a reparative response with proliferation of cholangiocytes and restoration of the biliary architecture, owing to the reactivation of a variety of morphogenetic signals. ...
Chronic diseases of the biliary tree (cholangiopathies) represent one of the major unmet needs in clinical hepatology and a si …
[Inflammatory and neoplastic cholangiopathies.]
Alvaro D, et al. Recenti Prog Med 2018 - Review. PMID 30667389 Italian.
The alteration of the normal function of cholangiocyte, can lead to the development of multiple biliary diseases, known as cholangiopathies, generally chronic, with a progressive course and which often are lacking of an effective treatment, determining a poor prognosis, even lethal, for the patient. ...Depending on their nature, these diseases are further subdivided into genetic, idiopathic, which include primary biliary cholangitis, primary sclerosing cholangitis and associated IgG4 cholangitis and malignant such as cholangiocarcinoma or mixed hepato-cholangiocarcinoma. ...
The alteration of the normal function of cholangiocyte, can lead to the development of multiple biliary diseases, known as cho …
Pathophysiology and Diseases of the Proximal Pathways of the Biliary System.
Nakanishi Y and Saxena R. Arch Pathol Lab Med 2015 - Review. PMID 26125426
CONTEXT: Diseases of the proximal pathways of the biliary system can be divided into those that affect the interlobular bile ducts and those that affect the bile canaliculi. ...OBJECTIVE: To summarize the current state of knowledge of diseases of the proximal pathways of the biliary system, with special emphasis on clinical presentation, pathological features, and differential diagnosis. ...
CONTEXT: Diseases of the proximal pathways of the biliary system can be divided into those that affect the interlobular bile d …
Proposal of a new disease concept "biliary diseases with pancreatic counterparts". Anatomical and pathological bases.
Nakanuma Y, et al. Histol Histopathol 2014 - Review. PMID 24108502
Herein, we propose that these non-neoplastic and neoplastic biliary diseases showing similarities to corresponding pancreatic diseases could be included in a new disease concept "biliary diseases with pancreatic counterparts". Based on this new concept, information obtained in biliary tract diseases could be applied to the analysis of pancreatic disease and vice versa, and also novel therapeutical strategies and molecular and genetic studies on pancreatic and biliary diseases may be developed with a unified approach....
Herein, we propose that these non-neoplastic and neoplastic biliary diseases showing similarities to corresponding pancreatic …
Functional role of cellular senescence in biliary injury.
Meng L, et al. Am J Pathol 2015 - Review. PMID 25619959 Free PMC article.
Senescence may play a role in biliary atresia, primary sclerosing cholangitis, cellular rejection, and primary biliary cirrhosis, four liver diseases affecting cholangiocytes and the biliary system. In this review, we examine proposed mechanisms of senescence-related biliary diseases, including hypotheses associated with the senescence-associated phenotype, induction of senescence in nearby cells, and the depletion of stem cell subpopulations. ...
Senescence may play a role in biliary atresia, primary sclerosing cholangitis, cellular rejection, and primary biliary cirrhos …
Hepatobiliary pathology.
Lefkowitch JH. Curr Opin Gastroenterol 2007 - Review. PMID 17414836
PURPOSE OF REVIEW: Recent papers on disorders of the liver and biliary tract which clarify their pathogenesis and attendant morphologic changes are highlighted. ...
PURPOSE OF REVIEW: Recent papers on disorders of the liver and biliary tract which clarify their pathogenesis and attendant mo …
8,055 results
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