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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 37
1782 18
1783 22
1784 27
1785 43
1786 60
1787 43
1788 33
1789 32
1790 44
1791 19
1792 33
1793 17
1794 18
1795 13
1796 15
1797 59
1798 15
1799 291
1800 377
1801 360
1802 283
1803 269
1804 289
1805 314
1806 282
1807 295
1808 289
1809 265
1810 267
1811 322
1812 238
1813 265
1814 285
1815 222
1816 315
1817 288
1818 303
1819 225
1820 213
1821 270
1822 247
1823 291
1824 269
1825 262
1826 385
1827 326
1828 467
1829 645
1830 569
1831 627
1832 313
1833 293
1834 287
1835 305
1836 271
1837 350
1838 484
1839 546
1840 695
1841 1154
1842 1487
1843 1118
1844 1248
1845 1278
1846 1404
1847 1367
1848 1204
1849 1208
1850 1125
1851 1228
1852 1309
1853 1559
1854 1306
1855 1587
1856 1587
1857 1488
1858 1541
1859 1562
1860 1632
1861 1275
1862 1112
1863 995
1864 1139
1865 1151
1866 1477
1867 1723
1868 1813
1869 1909
1870 1809
1871 2238
1872 2242
1873 2313
1874 2508
1875 2402
1876 2095
1877 2180
1878 2454
1879 2399
1880 2646
1881 3149
1882 2743
1883 3127
1884 3050
1885 3338
1886 3291
1887 3965
1888 4002
1889 4196
1890 4025
1891 3607
1892 4081
1893 4369
1894 3801
1895 4129
1896 4413
1897 4688
1898 4632
1899 4169
1900 3786
1901 3886
1902 3968
1903 3910
1904 4060
1905 4067
1906 3872
1907 4323
1908 4459
1909 4687
1910 4799
1911 5007
1912 4906
1913 5106
1914 5135
1915 4641
1916 4543
1917 4281
1918 4567
1919 4618
1920 4960
1921 4628
1922 4123
1923 4432
1924 4850
1925 4990
1926 5342
1927 5887
1928 5479
1929 5741
1930 5630
1931 5496
1932 5546
1933 5610
1934 5507
1935 5661
1936 5384
1937 5308
1938 5765
1939 5541
1940 4998
1941 4838
1942 4775
1943 4517
1944 4745
1945 20421
1946 53735
1947 64959
1948 70707
1949 62804
1950 85750
1951 103742
1952 108054
1953 108914
1954 105913
1955 108541
1956 107005
1957 111515
1958 109456
1959 109957
1960 112134
1961 120097
1962 125629
1963 141519
1964 162085
1965 176636
1966 179738
1967 191501
1968 207845
1969 215046
1970 218962
1971 222871
1972 227501
1973 230648
1974 234523
1975 248257
1976 250309
1977 249736
1978 258107
1979 265401
1980 267045
1981 271403
1982 282980
1983 294624
1984 302564
1985 318778
1986 331233
1987 347234
1988 363700
1989 377710
1990 382519
1991 379999
1992 381540
1993 389537
1994 400927
1995 410169
1996 420151
1997 417782
1998 435515
1999 452687
2000 489712
2001 501871
2002 519496
2003 547107
2004 590076
2005 648657
2006 695368
2007 731238
2008 778208
2009 817472
2010 879689
2011 953679
2012 1019834
2013 1070520
2014 1122543
2015 1162859
2016 1195070
2017 1215781
2018 1258910
2019 1315563
2020 1499035
2021 1637843
2022 1634805
2023 1541943
2024 1513424
2025 19558
2026 18

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35,629,779 results

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Quoted phrases not found in phrase index: "Agents Interacting With Transmitter", "Hormone Or Drug Receptors", "Nerve Growth Factor Agonist", "Protein L1l4", "Protein Nl1l4", "Priority Journal"
Page 1
GDNF, NGF and BDNF as therapeutic options for neurodegeneration.
Allen SJ, Watson JJ, Shoemark DK, Barua NU, Patel NK. Allen SJ, et al. Pharmacol Ther. 2013 May;138(2):155-75. doi: 10.1016/j.pharmthera.2013.01.004. Epub 2013 Jan 21. Pharmacol Ther. 2013. PMID: 23348013 Review.
Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are important for the survival, maintenance and regeneration of specific neuronal populations in the adult …
Glial cell-derived neurotrophic factor (GDNF), and the neurotrophin nerve growth factor (NGF) and brain-derived …
Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs.
Krautmann M, Walters R, Cole P, Tena J, Bergeron LM, Messamore J, Mwangi D, Rai S, Dominowski P, Saad K, Zhu Y, Guillot M, Chouinard L. Krautmann M, et al. Vet J. 2021 Oct;276:105733. doi: 10.1016/j.tvjl.2021.105733. Epub 2021 Aug 12. Vet J. 2021. PMID: 34391918 Free article.
Nerve growth factor (NGF), a critical mediator of nociception, is a novel analgesic therapeutic target. Bedinvetmab, a canine monoclonal antibody (mAb), binds NGF and inhibits its interaction with tropomyosin receptor kinase A (trkA) and p75 neurotroph …
Nerve growth factor (NGF), a critical mediator of nociception, is a novel analgesic therapeutic target. Bedinvetmab, a …
TRPC Channels and Programmed Cell Death.
Zhou J, Jia Y. Zhou J, et al. Adv Exp Med Biol. 2017;976:47-60. doi: 10.1007/978-94-024-1088-4_5. Adv Exp Med Biol. 2017. PMID: 28508312 Review.
Neurotrophins, including nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), bind to their high-affinity receptors to promote neuronal survival during brain development. ...The development and identification of TRPC channel …
Neurotrophins, including nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), bind to their h …
TrkA-mediated sensory innervation of injured mouse tendon supports tendon sheath progenitor cell expansion and tendon repair.
Cherief M, Xu J, Li Z, Tower RJ, Ramesh S, Qin Q, Gomez-Salazar M, Yea JH, Lee S, Negri S, Xu M, Price T, Kendal AR, Fan CM, Clemens TL, Levi B, James AW. Cherief M, et al. Sci Transl Med. 2023 Dec 20;15(727):eade4619. doi: 10.1126/scitranslmed.ade4619. Epub 2023 Dec 20. Sci Transl Med. 2023. PMID: 38117901
Here, we show that after Achilles tendon injury in mice, there is new nerve growth near tendon cells that express nerve growth factor (NGF). Conditional deletion of the Ngf gene in either myeloid or mesenchymal mouse cells limited both innervati …
Here, we show that after Achilles tendon injury in mice, there is new nerve growth near tendon cells that express nerve …
Modulation of neurotrophin signaling by monoclonal antibodies.
Rosenthal A, Lin JC. Rosenthal A, et al. Handb Exp Pharmacol. 2014;220:497-512. doi: 10.1007/978-3-642-45106-5_19. Handb Exp Pharmacol. 2014. PMID: 24668485 Review.
The neurotrophin family is comprised of the structurally related secreted proteins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophine-4 (NT-4). ...On the other hand trkB agonist a …
The neurotrophin family is comprised of the structurally related secreted proteins nerve growth factor (NGF), br …
Towards non invasive nerve growth factor therapies for Alzheimer's disease.
Cattaneo A, Capsoni S, Paoletti F. Cattaneo A, et al. J Alzheimers Dis. 2008 Oct;15(2):255-83. doi: 10.3233/jad-2008-15210. J Alzheimers Dis. 2008. PMID: 18953113 Review.
In the past thirty years, nerve growth factor (NGF) has received much attention for its potential role as a therapeutic agent for Alzheimer's disease (AD) due to its neurotrophic activities on basal forebrain cholinergic neurons. ...Thus, the concept o …
In the past thirty years, nerve growth factor (NGF) has received much attention for its potential role as a therapeutic …
Pharmacology of nerve growth factor and discovery of tanezumab, an anti-nerve growth factor antibody and pain therapeutic.
Hefti F. Hefti F. Pharmacol Res. 2020 Apr;154:104240. doi: 10.1016/j.phrs.2019.04.024. Epub 2019 Apr 23. Pharmacol Res. 2020. PMID: 31026504 Review.
The pharmacology of Nerve Growth Factor (NGF) and the discovery and development of tanezumab, a monoclonal anti-NGF antibody for the treatment of pain illustrate the complex and unpredictable nature of modern drug development. ...These events also refl …
The pharmacology of Nerve Growth Factor (NGF) and the discovery and development of tanezumab, a monoclonal anti-NGF ant …
Low-molecular mimetics of nerve growth factor and brain-derived neurotrophic factor: Design and pharmacological properties.
Gudasheva TA, Povarnina PY, Tarasiuk AV, Seredenin SB. Gudasheva TA, et al. Med Res Rev. 2021 Sep;41(5):2746-2774. doi: 10.1002/med.21721. Epub 2020 Aug 18. Med Res Rev. 2021. PMID: 32808322 Review.
To overcome the limitations of the clinical use of neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), scientists have been trying to create their low-molecular-weight mimetics having improved pharmacokinetic propertie …
To overcome the limitations of the clinical use of neurotrophins nerve growth factor (NGF) and brain-derived neurotroph …
Structure Diversity, Synthesis, and Biological Activity of Cyathane Diterpenoids in Higher Fungi.
Tang HY, Yin X, Zhang CC, Jia Q, Gao JM. Tang HY, et al. Curr Med Chem. 2015;22(19):2375-91. doi: 10.2174/0929867322666150521091333. Curr Med Chem. 2015. PMID: 25994862 Review.
These compounds show a diverse range of biological activities, such as antimicrobial, anti-MRSA, agonistic toward the kappa-opioid receptor, antiinflammatory, anti-proliferative and nerve growth factor (NGF)-like properties. ...
These compounds show a diverse range of biological activities, such as antimicrobial, anti-MRSA, agonistic toward the kappa-opioid re …
New and developing drugs for the treatment of neuropathic pain in diabetes.
Freeman R. Freeman R. Curr Diab Rep. 2013 Aug;13(4):500-8. doi: 10.1007/s11892-013-0396-6. Curr Diab Rep. 2013. PMID: 23771401 Review.
A number of agents from diverse pharmacological classes are used to treat neuropathic pain associated with diabetic peripheral neuropathy. ...These will include agonists and antagonists of the transient receptor potential channels, a fami …
A number of agents from diverse pharmacological classes are used to treat neuropathic pain associated with diabetic …
35,629,779 results
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