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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1966 5
1967 13
1968 11
1969 11
1970 14
1971 18
1972 25
1973 33
1974 46
1975 62
1976 53
1977 47
1978 60
1979 60
1980 65
1981 63
1982 71
1983 62
1984 54
1985 84
1986 74
1987 73
1988 85
1989 133
1990 132
1991 148
1992 139
1993 194
1994 163
1995 166
1996 167
1997 212
1998 185
1999 171
2000 255
2001 210
2002 240
2003 321
2004 310
2005 327
2006 357
2007 357
2008 368
2009 373
2010 407
2011 513
2012 494
2013 463
2014 476
2015 530
2016 536
2017 520
2018 497
2019 243
2020 2
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9,788 results
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Page 1
Blastocyst metabolism.
Gardner DK and Harvey AJ. Reprod Fertil Dev 2015 - Review. PMID 25751298
The mammalian blastocyst exhibits an idiosyncratic metabolism, reflecting its unique physiology and its ability to undergo implantation. ...It is evident that blastocyst metabolism regulates more than the production of ATP; rather, it is apparent that metabolites and cofactors are important regulators of the epigenome, putting metabolism at centre stage when considering the interactions of the blastocyst with its environment....
The mammalian blastocyst exhibits an idiosyncratic metabolism, reflecting its unique physiology and its ability to undergo imp …
Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos
Petropoulos S, et al. Cell 2016. PMID 27062923 Free PMC article.
These data show that cells undergo an intermediate state of co-expression of lineage-specific genes, followed by a concurrent establishment of the trophectoderm, epiblast, and primitive endoderm lineages, which coincide with blastocyst formation. ...
These data show that cells undergo an intermediate state of co-expression of lineage-specific genes, followed by a concurrent establishment …
Epigenetic differences between naïve and primed pluripotent stem cells
Takahashi S, et al. Cell Mol Life Sci 2018 - Review. PMID 29134247 Free PMC article.
The naïve state represents the cellular state of the preimplantation mouse blastocyst inner cell mass, while the primed state is representative of the post-implantation epiblast cells. These two cell types exhibit clearly distinct developmental potential, as evidenced by the fact that naïve cells are able to contribute to blastocyst chimeras, while primed cells cannot. ...
The naïve state represents the cellular state of the preimplantation mouse blastocyst inner cell mass, while the primed state is repr …
Evaluation of a novel non-invasive preimplantation genetic screening approach
Kuznyetsov V, et al. PLoS One 2018. PMID 29746572 Free PMC article.
OBJECTIVE: To assess whether embryonic DNA isolated from blastocyst culture conditioned medium (BCCM) combined with blastocoel fluid (BF) could be used for blastocyst stage non-invasive preimplantation genetic testing for chromosomal aneuploidy (non-invasive preimplantation genetic screening, NIPGS). ...INTERVENTIONS: DNA analysis of combined BCCM plus BF in comparison with trophectoderm (TE) biopsy and/or whole blastocyst (WB)using next generation sequencing (NGS). ...
OBJECTIVE: To assess whether embryonic DNA isolated from blastocyst culture conditioned medium (BCCM) combined with blastocoel fluid …
The mammalian blastocyst.
Frankenberg SR, et al. Wiley Interdiscip Rev Dev Biol 2016 - Review. PMID 26799266
The principal drivers in blastocyst evolution were loss of yolk coupled with evolution of the placenta. An important outcome of blastocyst development is differentiation of two extraembryonic lineages (trophoblast and hypoblast) that contribute to the placenta. While in many species trophoblast segregation is often coupled with blastocyst formation, in marsupials and at least some Afrotherians, these events do not coincide. ...
The principal drivers in blastocyst evolution were loss of yolk coupled with evolution of the placenta. An important outcome of bl
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