Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2014 1
2015 3
2016 2
2017 2
2018 2
2019 3
2020 1
2021 2
2023 7
2024 11
2025 8
2026 4

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

38 results

Results by year

Filters applied: . Clear all
Page 1
High-precision automated bone age: a clinically useful tool in monitoring of treatment effects in children and adolescents.
Thodberg HH, Aksglaede L, Juul A, Davis SM, Ross J. Thodberg HH, et al. Sci Rep. 2026 Apr 27;16(1):19402. doi: 10.1038/s41598-026-49670-1. Sci Rep. 2026. PMID: 42045323 Free PMC article.
The objective of this work was to determine the precision of automated bone age and bone health index (BHI) measurements by BoneXpert and to establish the time interval at which the automated method can detect a significant treatment effect. ...
The objective of this work was to determine the precision of automated bone age and bone health index (BHI) measurement …
Current applications and challenges of artificial intelligence applied to diagnostics in pediatric musculoskeletal imaging.
Simoni P, Francavilla M, Omoumi P, Aparisi Gomez MP, Giraudo C, Boitsios G. Simoni P, et al. Pediatr Radiol. 2026 Apr 1. doi: 10.1007/s00247-026-06561-x. Online ahead of print. Pediatr Radiol. 2026. PMID: 41920351 Review.
Until recently, the use of AI was limited to evaluating bone age and opportunistically assessing the bone health index. Currently, validated AI software for commercial use includes the detection of appendicular fractures, automated measurement of scoliosis, a …
Until recently, the use of AI was limited to evaluating bone age and opportunistically assessing the bone health index. …
Comparative study of the performance of two versions of the same AI tool for pediatric skeletal maturation assessment.
Boitsios G, Saliba T, Simoni P. Boitsios G, et al. Eur Radiol. 2026 Jun;36(6):4714-4724. doi: 10.1007/s00330-025-12265-x. Epub 2026 Jan 7. Eur Radiol. 2026. PMID: 41498826
OBJECTIVES: To compare BoneXpert version 3 with version 2 in estimating bone age and bone health index (BHI), focusing on mean absolute error (MAE) and root mean square error (RMSE) in healthy children. ...
OBJECTIVES: To compare BoneXpert version 3 with version 2 in estimating bone age and bone health index (BHI), focusing …
Bone Health Index (BoneXpert) and parameters of peripheral quantitative computed tomography indicate overall adequate bone health in adolescents with chronic endocrine diseases at time of transition.
Gippert S, Bettendorf M, Hoos J, Choukair D. Gippert S, et al. PLoS One. 2025 Dec 4;20(12):e0337842. doi: 10.1371/journal.pone.0337842. eCollection 2025. PLoS One. 2025. PMID: 41343454 Free PMC article.
Peripheral quantitative computed tomography (pQCT) is used to quantify bone health. A new automated Bone Health Index (BHI) determination (BoneXpertTM) is available using digitized X-rays of the left hand taken for bone age (Greulich&Pyle, BA) determinati …
Peripheral quantitative computed tomography (pQCT) is used to quantify bone health. A new automated Bone Health Index ( …
Longitudinal course of bone health from infancy to mid-adulthood in preterm and term-born individuals.
Brecher J, Chaouch A, Konrad D, Eichelberger DA, Latal B, Jenni OG, Lenherr-Taube N, Wehrle FM. Brecher J, et al. Sci Rep. 2025 Nov 26;15(1):45371. doi: 10.1038/s41598-025-29584-0. Sci Rep. 2025. PMID: 41298945 Free PMC article.
Bone health was measured longitudinally using the Bone Health Index (BHI) from hand X-rays analyzed by BoneXpert. Fracture history was obtained through parental interviews and self-reports. ...
Bone health was measured longitudinally using the Bone Health Index (BHI) from hand X-rays analyzed by BoneXpert. Fract …
Hand X-ray metrics for assessing bone health and fracture risk in Duchenne muscular dystrophy: a cross-sectional study.
Panicucci C, Repetto A, Angelelli A, Bovis F, Casalini S, Brolatti N, Trucco F, Pedemonte M, Damasio MB, Maghnie M, Bruno C, Di Iorgi N. Panicucci C, et al. Eur J Pediatr. 2025 Nov 17;184(12):767. doi: 10.1007/s00431-025-06619-2. Eur J Pediatr. 2025. PMID: 41247392
Dual-energy X-ray absorptiometry (DXA) is the standard for bone mineral density (BMD) assessment, but its interpretation is often limited in DMD due to scoliosis and/or surgical instrumentation. The bone health index (BHI), derived from hand X-rays using the …
Dual-energy X-ray absorptiometry (DXA) is the standard for bone mineral density (BMD) assessment, but its interpretation is often limited in …
Automated bone age calculation is an independent predictor of vertebral fracture burden in Duchenne muscular dystrophy.
Phung K, Rauch D, Jackowski S, Scharke M, Koujok K, Matzinger MA, Shenouda N, Jaremko JL, Wilson N, Jalbout RE, Santos R, Khan N, Wang M, McAdam L, McMillan HJ, Ma J, Siminoski K, Ward LM. Phung K, et al. Osteoporos Int. 2025 Nov;36(11):2287-2297. doi: 10.1007/s00198-025-07681-0. Epub 2025 Oct 21. Osteoporos Int. 2025. PMID: 41120763
Furthermore, BA delay as determined by both radiologists and BoneXpert, and the BoneXpert-derived Bone Health Index Z-score (a surrogate for bone strength), were associated with spinal fragility. PURPOSE: To compare BA assessed by experienced radiologists ver …
Furthermore, BA delay as determined by both radiologists and BoneXpert, and the BoneXpert-derived Bone Health Index Z-s …
Real-World Efficacy of Weekly Somatrogon on Growth and Bone Health in Pediatric Growth Hormone Deficiency: A 12-Month Retrospective Cohort Study.
Awad MH, Ghanim R, Eladl R, Mughal Z, Mustafa M. Awad MH, et al. J Clin Res Pediatr Endocrinol. 2026 Jul 1;18(2):254-260. doi: 10.4274/jcrpe.galenos.2025.2025-6-24. Epub 2025 Sep 30. J Clin Res Pediatr Endocrinol. 2026. PMID: 41025548 Free PMC article.
Growth outcomes and bone health indices were assessed over 12 months using auxology, insulin-like growth factor 1 (IGF-1) levels, and BoneXpert-derived bone health index (BHI) SDS and Metacarpal Index (MCI) SDS. RESULTS: The study cohort consisted of 39 child …
Growth outcomes and bone health indices were assessed over 12 months using auxology, insulin-like growth factor 1 (IGF-1) levels, and BoneXp …
Cortical bone status and its determinants in pediatric Klinefelter syndrome.
Hickmann M, Nauwynck E, Ernst C, Willekens I, Anckaert E, Vanbesien J, Staels W, De Schepper J, Gies I. Hickmann M, et al. Endocr Connect. 2025 Aug 28;14(8):e250216. doi: 10.1530/EC-25-0216. Print 2025 Aug 1. Endocr Connect. 2025. PMID: 40808370 Free PMC article.
METHODS: In a cohort of 50 pediatric patients with KS, we retrospectively collected anthropometric measurements, bone health index (BHI), and bone age readings by the BoneXpert method. Digit 2 (D2) and 4 (D4) lengths and ratio were calculated. ...
METHODS: In a cohort of 50 pediatric patients with KS, we retrospectively collected anthropometric measurements, bone health …
38 results