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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 2
1948 1
1949 2
1956 3
1958 3
1959 2
1961 4
1962 2
1964 1
1965 2
1970 2
1971 13
1972 47
1973 41
1974 62
1975 35
1976 37
1977 41
1978 45
1979 42
1980 34
1981 33
1982 39
1983 49
1984 51
1985 67
1986 66
1987 62
1988 57
1989 79
1990 85
1991 84
1992 121
1993 99
1994 88
1995 100
1996 80
1997 75
1998 97
1999 78
2000 80
2001 99
2002 102
2003 147
2004 121
2005 140
2006 123
2007 127
2008 151
2009 193
2010 182
2011 185
2012 176
2013 159
2014 125
2015 107
2016 87
2017 88
2018 92
2019 24
2020 1
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4,052 results
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Page 1
Decellularized Bone Matrix Scaffold for Bone Regeneration.
Chen G and Lv Y. Methods Mol Biol 2018. PMID 28770492
Decellularized bone matrix is gaining a lot of attention as implantable biomaterials and/or biological scaffolds for bone tissue repair, and shows good clinical performance. ...Fabrication and application of the hydrogel derived from decellularized bone for bone tissue engineering are also presented....
Decellularized bone matrix is gaining a lot of attention as implantable biomaterials and/or biological scaffolds for bone
The Role of Matrix Composition in the Mechanical Behavior of Bone.
Unal M, et al. Curr Osteoporos Rep 2018 - Review. PMID 29611037 Free PMC article.
PURPOSE OF REVIEW: While thinning of the cortices or trabeculae weakens bone, age-related changes in matrix composition also lower fracture resistance. ...Clinical tools sensitive to age- and disease-related changes in matrix composition that the affect mechanical behavior of bone could potentially improve fracture risk assessment....
PURPOSE OF REVIEW: While thinning of the cortices or trabeculae weakens bone, age-related changes in matrix composition also l …
The "love-hate" relationship between osteoclasts and bone matrix.
Rucci N and Teti A. Matrix Biol 2016 - Review. PMID 26921625
Osteoclasts are unique cells that destroy the mineralized matrix of the skeleton. There is a "love-hate" relationship between the osteoclasts and the bone matrix, whereby the osteoclast is stimulated by the contact with the matrix but, at the same time, it disrupts the matrix, which, in turn, counteracts this disruption by some of its components. ...Expanding the knowledge on osteoclast-to-matrix interaction could help to counteract these diseases and improve the human bone health. ...
Osteoclasts are unique cells that destroy the mineralized matrix of the skeleton. There is a "love-hate" relationship between the ost …
3D-Printing Composite Polycaprolactone-Decellularized Bone Matrix Scaffolds for Bone Tissue Engineering Applications.
Rindone AN, et al. Methods Mol Biol 2018. PMID 28493213
Tissue engineered (TE) bone grafts have the potential to provide a more effective treatment than current bone grafts since they would restore fully functional bone tissue in large defects. ...Using 3D-printing, composite polycaprolactone (PCL) and decellularized bone matrix (DCB) scaffolds can be produced to have the desired mechanical properties, geometry, and osteoinductivity needed for a TE bone graft. ...
Tissue engineered (TE) bone grafts have the potential to provide a more effective treatment than current bone grafts since the …
Bone matrix microdamage and vascular changes characterize bone marrow lesions in the subchondral bone of knee osteoarthritis.
Muratovic D, et al. Bone 2018. PMID 29331302
The aim of this study was to investigate the relationship between BMLs in the tibial plateau (TP) of knee OA and bone matrix microdamage, osteocyte density and vascular changes. ...CONCLUSIONS: Increased bone matrix microdamage and altered vasculature in the subchondral bone of BMLs is consistent with overloading and vascular contributions to the formation of these lesions. ...
The aim of this study was to investigate the relationship between BMLs in the tibial plateau (TP) of knee OA and bone matrix m …
Xenogeneic bone matrix immune risk assessment using GGTA1 knockout mice.
Shao A, et al. Artif Cells Nanomed Biotechnol 2018. PMID 30207744
In this study, we prepared lyophilized bone substitutes (T1) and Guanghao Biotech bone substitutes (T2, animal-derived biomaterials with α-Gal antigen decreased), aimed to assess the immune risk of xenografts bone substitutes on GGTA1 knockout mice. ...In vitro results showed that the amount of α-Gal epitopes in T1 bone substitutes was significantly higher than T2 bone substitutes, and the clearance rate of α-Gal antigen in T2 bone substitutes achieved about 55.6%. ...
In this study, we prepared lyophilized bone substitutes (T1) and Guanghao Biotech bone substitutes (T2, animal-derived biomate …
Apelin-13 deficiency alters cortical bone geometry, organic bone matrix, and inhibits Wnt/β-catenin signaling.
Han XF, et al. Gen Comp Endocrinol 2018. PMID 29857005
Apelin-13 deficient mice were set up and cortical bone geometry was measured with micro-computed tomography (Micro-CT) at 5 months old, then profile of organic bone matrix genes was detected with quantitative Real-Time PCR (qRT-PCR). ...The decrease in bone formation in Apelin-13 deficient mice is associated with downregulation of organic bone matrix genes and Wnt/β-catenin signaling molecules, all of these indicate that association of Apelin-13 with bone mineral density (BMD) could be mediated by Wnt/β-catenin pathway....
Apelin-13 deficient mice were set up and cortical bone geometry was measured with micro-computed tomography (Micro-CT) at 5 months ol …
Demineralized bone-matrix-induced osteogenesis.
Harakas NK. Clin Orthop Relat Res 1984 - Review. PMID 6380863
A review of the literature on bone formation induced by demineralized bone and dentin indicates that: there is considerable interest in the biology and applied science of osteoinduction; the technology has been developed, but it varies in detail from one laboratory to another because of specific and individual objectives; and the accumulated evidence supports the concept of cartilage and bone cell differentiation induced by a unique bone morphogenetic protein (BMP)....
A review of the literature on bone formation induced by demineralized bone and dentin indicates that: there is considerable in …
Demineralized bone matrix and human cancellous bone enhance fixation of porous-coated titanium implants in sheep.
Babiker H, et al. J Tissue Eng Regen Med 2016. PMID 23349100
Allogenic bone graft has been considered the gold standard in connection with bone graft material in revision joint arthroplasty. ...The use of osteoinductive materials, such as demineralized bone matrix (DBM), alone or in combination with allograft or commercially available human cancellous bone (CB), may replace allografts, as they have the capability of inducing new bone and improving implant fixation through enhancing bone ongrowth. ...
Allogenic bone graft has been considered the gold standard in connection with bone graft material in revision joint arthroplas …
Bone Matrix Composition Following PTH Treatment is Not Dependent on Sclerostin Status.
Ross RD, et al. Calcif Tissue Int 2016. PMID 26514840
Humeral trabecular and cortical bone sites from 16 week old male wild-type (WT) and sclerostin knockout (KO) mice, which had been treated with vehicle or iPTH from age 10-16 weeks, were examined by micro-computed tomography (µCT) to measure bone volume, backscatter scanning electron microscopy (bSEM) to assess global mineralization, and Fourier transform infrared microspectroscopy (FTIRM) to examine matrix composition (mineral-to-matrix ratio, crystallinity, collagen cross-link ratio, and carbonate substitution). ...Compared to WT mice, sclerostin KO mice had higher trabecular and cortical bone mass (p < 0.001) and lower mineral-to-matrix ratio in the trabecular (p = 0.010) and cortical (p = 0.016) compartments. ...
Humeral trabecular and cortical bone sites from 16 week old male wild-type (WT) and sclerostin knockout (KO) mice, which had been tre …
4,052 results
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