Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 2
1972 3
1973 6
1974 9
1975 6
1976 4
1977 3
1978 7
1979 1
1981 3
1982 3
1983 2
1984 5
1985 4
1986 4
1987 3
1988 2
1989 6
1990 5
1991 8
1992 8
1993 11
1994 3
1995 13
1996 7
1997 15
1998 15
1999 15
2000 13
2001 15
2002 9
2003 23
2004 12
2005 13
2006 11
2007 11
2008 15
2009 25
2010 30
2011 27
2012 30
2013 37
2014 27
2015 18
2016 10
2017 5
2018 12
2019 4
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

474 results
Results by year
Filters applied: . Clear all
Page 1
The "love-hate" relationship between osteoclasts and bone matrix.
Rucci N and Teti A. Matrix Biol 2016 - Review. PMID 26921625
Osteoclasts are unique cells that destroy the mineralized matrix of the skeleton. There is a "love-hate" relationship between the osteoclasts and the bone matrix, whereby the osteoclast is stimulated by the contact with the matrix but, at the same time, it disrupts the matrix, which, in turn, counteracts this disruption by some of its components. ...Expanding the knowledge on osteoclast-to-matrix interaction could help to counteract these diseases and improve the human bone health. ...
Osteoclasts are unique cells that destroy the mineralized matrix of the skeleton. There is a "love-hate" relationship between the ost …
Bone matrix microdamage and vascular changes characterize bone marrow lesions in the subchondral bone of knee osteoarthritis.
Muratovic D, et al. Bone 2018. PMID 29331302
The aim of this study was to investigate the relationship between BMLs in the tibial plateau (TP) of knee OA and bone matrix microdamage, osteocyte density and vascular changes. ...CONCLUSIONS: Increased bone matrix microdamage and altered vasculature in the subchondral bone of BMLs is consistent with overloading and vascular contributions to the formation of these lesions. ...
The aim of this study was to investigate the relationship between BMLs in the tibial plateau (TP) of knee OA and bone matrix m …
Gaucher disease iPSC-derived osteoblasts have developmental and lysosomal defects that impair bone matrix deposition.
Panicker LM, et al. Hum Mol Genet 2018. PMID 29301038 Free PMC article.
GD osteoblasts were also defective in their ability to carry out Ca2+-dependent exocytosis, a lysosomal function that is necessary for bone matrix deposition. ...Furthermore, the rescue of bone matrix deposition by pharmacological activation of Wnt/β catenin in GD osteoblasts uncovers a new therapeutic target for the treatment of bone abnormalities in GD....
GD osteoblasts were also defective in their ability to carry out Ca2+-dependent exocytosis, a lysosomal function that is necessary for bo
Bone matrix production in hydroxyapatite-modified hydrogels suitable for bone bioprinting.
Wenz A, et al. Biofabrication 2017. PMID 28990579
Those changes in rheological material characteristics indicate a distinct change in elastic and viscous hydrogel properties, and are attributed to extensive matrix production in the hydrogels by the encapsulated cells, what could also be proven by staining of bone matrix components like collagen I, fibronectin, alkaline phosphatase and osteopontin. ...Again, an intense matrix formation as well as upregulation of osteogenic markers by the encapsulated cells could be shown. In conclusion, we demonstrated that our HAp-containing bioinks and hydrogels on basis of methacrylated gelatin and hyaluronic acid are on the one hand highly suitable for the build-up of relevant three-dimensional geometries with microextrusion bioprinting, and on the other hand exhibit a significant positive effect on bone matrix development and remodeling in the hydrogels, as indicated by rheological measurements and staining of bone components. ...
Those changes in rheological material characteristics indicate a distinct change in elastic and viscous hydrogel properties, and are attribu …
Xenogeneic bone matrix immune risk assessment using GGTA1 knockout mice.
Shao A, et al. Artif Cells Nanomed Biotechnol 2018. PMID 30207744
In this study, we prepared lyophilized bone substitutes (T1) and Guanghao Biotech bone substitutes (T2, animal-derived biomaterials with α-Gal antigen decreased), aimed to assess the immune risk of xenografts bone substitutes on GGTA1 knockout mice. ...In vitro results showed that the amount of α-Gal epitopes in T1 bone substitutes was significantly higher than T2 bone substitutes, and the clearance rate of α-Gal antigen in T2 bone substitutes achieved about 55.6%. ...
In this study, we prepared lyophilized bone substitutes (T1) and Guanghao Biotech bone substitutes (T2, animal-derived biomate …
Bone matrix development in steroid-induced osteoporosis is associated with a consistently reduced fibrillar stiffness linked to altered bone mineral quality.
Xi L, et al. Acta Biomater 2018. PMID 29902593 Free PMC article.
Here we combine experimental X-ray nanoscale mechanical imaging with analytical modelling of the bone matrix mechanics to determine mechanisms causing bone material quality deterioration during development of GIOP. ...We develop a two-level hierarchical model of the bone matrix (mineralized fibril and lamella) to predict fibrillar mechanical response as a function of architectural parameters of the mineralized matrix. ...
Here we combine experimental X-ray nanoscale mechanical imaging with analytical modelling of the bone matrix mechanics to dete …
The pathology of bone tissue during peri-implantitis.
Schminke B, et al. J Dent Res 2015. PMID 25406169 Free PMC article.
Here, we describe the gene and protein expression patterns of peri-implantitis bone tissue compared with healthy peri-implant bone tissue. ...The levels of typical bone matrix molecules, including SPP1, BGLAP, and COL9A1, in patients with peri-implantitis were reduced, while the inflammation marker interleukin 8 (IL8) was highly expressed. ...
Here, we describe the gene and protein expression patterns of peri-implantitis bone tissue compared with healthy peri-implant bone
Experimental Evaluation of the Effectiveness of Demineralized Bone Matrix and Collagenated Heterologous Bone Grafts Used Alone or in Combination with Platelet-Rich Fibrin on Bone Healing in Sinus Floor Augmentation.
Peker E, et al. Int J Oral Maxillofac Implants 2016. PMID 27004298
CONCLUSION: There is no beneficial effect of the application of PRF in combination with demineralized bone matrix or collagenated heterologous bone graft on bone formation in sinus floor augmentation. The results of this study showed that both collagenated heterologous bone graft and demineralized bone matrix have osteoconductive properties, but demineralized bone matrix showed more bone formation than collagenated heterologous bone graft....
CONCLUSION: There is no beneficial effect of the application of PRF in combination with demineralized bone matrix or collagena …
Multiscale alterations in bone matrix quality increased fragility in steroid induced osteoporosis.
Karunaratne A, et al. Bone 2016. PMID 26657825 Free PMC article.
This rapid increase in bone fracture risk is largely independent of bone loss (quantity), and must therefore arise from degradation of the quality of the bone matrix at the micro- and nanoscale. ...Here we demonstrate alterations in the nanostructural parameters of the mineralized fibrillar collagen matrix, which affect bone quality, and develop a model linking these to increased fracture risk in glucocorticoid induced osteoporosis. ...
This rapid increase in bone fracture risk is largely independent of bone loss (quantity), and must therefore arise from degrad …
Enhanced osteoinductive capacity and decreased variability by enrichment of demineralized bone matrix with a bone protein extract.
Ramis JM, et al. J Mater Sci Mater Med 2018. PMID 29956013
Osteoinductive capacity of demineralized bone matrix (DBM) is sometimes insufficient or shows high variability between different batches of DBM. ...Then, we tested the enrichment of DBM with a bone protein extract (BPE) containing osteogenic growth factors comparing two sources: cortical bone powder and DBM. ...
Osteoinductive capacity of demineralized bone matrix (DBM) is sometimes insufficient or shows high variability between differe …
474 results
Jump to page
Feedback