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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1972 5
1973 5
1974 6
1975 7
1976 5
1977 1
1978 4
1979 8
1980 2
1981 9
1982 10
1983 5
1984 8
1985 10
1986 11
1987 12
1988 15
1989 16
1990 20
1991 19
1992 18
1993 27
1994 11
1995 12
1996 13
1997 9
1998 27
1999 23
2000 33
2001 45
2002 31
2003 59
2004 38
2005 47
2006 37
2007 35
2008 72
2009 73
2010 75
2011 74
2012 60
2013 49
2014 25
2015 18
2016 11
2017 13
2018 13
2019 2
2020 0
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1,046 results
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Page 1
Supplying osteogenesis to dead bone using an osteogenic matrix cell sheet.
Uchihara Y, et al. J Orthop Sci 2018. PMID 29478622
Osteogenic matrix cell sheets were created from rat bone marrow-derived stromal cells (BMSCs). After wrapping the dead bone with an osteogenic matrix cell sheet, it was subcutaneously transplanted into the back of a rat and harvested after 4 weeks. ...CONCLUSION: Our study indicates that osteogenic matrix cell sheet transplantation can supply osteogenesis to dead bone....
Osteogenic matrix cell sheets were created from rat bone marrow-derived stromal cells (BMSCs). After wrapping the dead bone
Xenogeneic bone matrix immune risk assessment using GGTA1 knockout mice.
Shao A, et al. Artif Cells Nanomed Biotechnol 2018. PMID 30207744
The immune risk can be prevented by depletion or breaking anti-Gal antibody prior to transplant. Therefore, how to assess the immune risk of the bone substitutes and select the reliable animal research model become extremely important. ...In vitro results showed that the amount of α-Gal epitopes in T1 bone substitutes was significantly higher than T2 bone substitutes, and the clearance rate of α-Gal antigen in T2 bone substitutes achieved about 55.6%. ...
The immune risk can be prevented by depletion or breaking anti-Gal antibody prior to transplant. Therefore, how to assess the immune …
A comparison between autograft alone, bone cement, and demineralized bone matrix in cranioplasty.
Plum AW and Tatum SA. Laryngoscope 2015. PMID 25641743
The patients were divided based on whether bone autograft, demineralized bone matrix, or bone cement was used for reconstruction of their craniofacial defect. ...However, residual bone defects and the need for a revision cranioplasty were higher in the bone matrix group. Likewise, patient, parent, and surgeon satisfaction with the appearance was lower in the bone matrix group. ...
The patients were divided based on whether bone autograft, demineralized bone matrix, or bone cement was used fo …
Demineralized bone matrix in anterior cervical discectomy and fusion: a systematic review.
Zadegan SA, et al. Eur Spine J 2017 - Review. PMID 27832365
Demineralized bone matrix (DBM) is one of the fusion options that has been used in treatment of the bone defects for years. The purpose of this review is to provide an evidence-based analysis on the current evidence for effectiveness of DBM in ACDF. ...Patient-reported outcomes were non-inferior for DBM compared with the autograft and other bone substitute materials. The DBM had a fusion rate comparable with other graft materials, particularly in long term (88.8-100%, after 18 months follow-up). ...
Demineralized bone matrix (DBM) is one of the fusion options that has been used in treatment of the bone defects for ye …
Bone matrix-induced local bone induction.
Muthukumaran N and Reddi AH. Clin Orthop Relat Res 1985 - Review. PMID 3905107
The sequential cellular changes in the implants in response to collagenous bone matrix-induced local bone formation include: binding of fibronectin to matrix, chemotaxis and attachment of progenitor cells, proliferation and differentiation of progenitor cells into chondrocytes, and finally osteogenesis and marrow differentiation. ...It is noteworthy that gel filtration fractions of rat chondrosarcoma on Sepharose CL-6B are inhibitory to bone inductive potential of demineralized rat bone matrix....
The sequential cellular changes in the implants in response to collagenous bone matrix-induced local bone formation inc …
Bone repair of surgical defects filled with autogenous bone and covered with demineralized bone matrix membrane or polytetrafluoroethylene membrane in rats.
Borrasca AG, et al. Int J Oral Maxillofac Implants 2015. PMID 25830405
Sites treated with demineralized bone matrix membrane showed, as early as day 10, more newly formed bone and slow replacement until day 60. ...CONCLUSION: The demineralized bone matrix membrane proved to be biocompatible. In terms of newly formed bone area, both membranes showed similar performance....
Sites treated with demineralized bone matrix membrane showed, as early as day 10, more newly formed bone and slow repla …
Regenerative surgical therapy for peri-implantitis using deproteinized bovine bone mineral with 10% collagen, enamel matrix derivative and Doxycycline-A prospective 3-year cohort study.
Mercado F, et al. Clin Oral Implants Res 2018. PMID 29767434
The aim of this study was to evaluate a combination therapy of deproteinized bovine bone mineral with 10% collagen (DBBMC), enamel matrix derivative (EMD) and Doxycycline in the regeneration of bone defects associated with peri-implantitis. ...Clinical measurements included probing depths, recession, radiographic bone fill, gingival inflammation and bleeding on probing/suppuration. ...
The aim of this study was to evaluate a combination therapy of deproteinized bovine bone mineral with 10% collagen (DBBMC), enamel …
Mechanisms of action of demineralized bone matrix in the repair of cortical bone defects.
Colnot C, et al. Clin Orthop Relat Res 2005. PMID 15930923
We tested this possibility by comparing demineralized bone matrix combined with hyaluronan with heat-inactivated demineralized bone matrix combined with hyaluronan and found that the intact material was superior in terms of its ability to stimulate new bone formation. ...Therefore, demineralized bone matrix combined with hyaluronan may not only attract osteoblasts and stimulate their differentiation, but also induce bone matrix resorption, which is a critically important regulator of bone formation and mineralization....
We tested this possibility by comparing demineralized bone matrix combined with hyaluronan with heat-inactivated demineralized …
Growth factors in orthopaedic surgery: demineralized bone matrix versus recombinant bone morphogenetic proteins.
Hinsenkamp M and Collard JF. Int Orthop 2015 - Review. PMID 25338109
For clinical implantation the two main options are demineralised bone matrix (DBM) and recombinant bone morphogenetic proteins (rhBMP). Many clinical studies agree on an equivalent osteoinductive effect between DBM, BMPs and autologous bone graft; however, the different origins and processing of DBM and rhBMP may introduce some fluctuations. ...
For clinical implantation the two main options are demineralised bone matrix (DBM) and recombinant bone morphogenetic p …
Fibular Allograft and Demineralized Bone Matrix for the Treatment of Slipped Capital Femoral Epiphysis.
Murray T, et al. Orthopedics 2016. PMID 27135447
This study describes the results of using a 10-mm diameter premilled fibular allograft packed with demineralized bone matrix placed across the physis in an open surgical approach under image intensification. A review identified 45 cases of BGE using fibular allograft and demineralized bone matrix in 34 patients with a diagnosis of SCFE performed by a single surgeon during an 8-year period. ...
This study describes the results of using a 10-mm diameter premilled fibular allograft packed with demineralized bone matrix p …
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