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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 2
1996 15
1997 12
1998 24
1999 27
2000 29
2001 31
2002 36
2003 39
2004 49
2005 66
2006 64
2007 63
2008 67
2009 84
2010 87
2011 77
2012 99
2013 114
2014 101
2015 101
2016 80
2017 84
2018 53
2019 26
2020 0
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1,292 results
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The Bone Morphogenetic Proteins and Their Antagonists.
Mulloy B and Rider CC. Vitam Horm 2015 - Review. PMID 26279373
The bone morphogenetic proteins (BMPs) and the growth and differentiation factors comprise a single family of some 20 homologous, dimeric cytokines which share the cystine-knot domain typical of the TGF-β superfamily. They control the differentiation and activity of a range of cell types, including many outside bone and cartilage. They serve as developmental morphogens, but are also important in chronic pathologies, including tissue fibrosis and cancer. ...
The bone morphogenetic proteins (BMPs) and the growth and differentiation factors comprise a single family of some 20 h …
Bone morphogenetic proteins - 7 and - 2 in the treatment of delayed osseous union secondary to bacterial osteitis in a rat model.
Helbig L, et al. BMC Musculoskelet Disord 2018. PMID 30049273 Free PMC article.
Results from a semiquantitative bone-healing-score revealed best bone-healing in the non-infected control group. The expected chronic infection was confirmed in all infected groups. CONCLUSIONS: In delayed bone healing secondary to infection rhBMP treatment promotes bone healing with no significant differences in the healing efficacy of rhBMP-2 and rhBMP-7 being noted. ...
Results from a semiquantitative bone-healing-score revealed best bone-healing in the non-infected control group. The expected …
Formulation, Delivery and Stability of Bone Morphogenetic Proteins for Effective Bone Regeneration.
El Bialy I, et al. Pharm Res 2017 - Review. PMID 28342056 Free PMC article.
Bone morphogenetic proteins (BMPs) are responsible for bone formation during embryogenesis and bone regeneration and remodeling. The osteoinductive action of BMPs, especially BMP-2 and BMP-7, has led to their use in a range of insurmountable treatments where intervention is required for effective bone regeneration. ...
Bone morphogenetic proteins (BMPs) are responsible for bone formation during embryogenesis and bone regen
Bone morphogenetic proteins for articular cartilage regeneration.
Deng ZH, et al. Osteoarthritis Cartilage 2018 - Review. PMID 29580979 Free article.
Bone morphogenetic proteins (BMPs) play important roles in bone and cartilage formation. This article reviews the experimental and clinical applications of BMPs in cartilage regeneration. ...However, the development of BMP therapy as a treatment modality for cartilage regeneration has been hampered by certain factors, such as the eligibility of participants in clinical trials, financial support, drug delivery carrier safety, availabilities of effective scaffolds, appropriate selection of optimal dose and timing of administration, and side effects. ...
Bone morphogenetic proteins (BMPs) play important roles in bone and cartilage formation. This article reviews th
[Bone morphogenetic proteins (BMP): clinical application for reconstruction of bone defects].
Sierra-García GD, et al. Gac Med Mex 2016 - Review. PMID 27335195 Spanish. Free article.
Since the introduction of bone morphogenetic proteins, their use has become an invaluable ally for the treatment of bone defects. ...In this review, the roles of bone morphogenetic proteins in bone repair and clinical applications are analyzed. These findings represent advances in the study of bone regeneration and application of growth factors for more predictable results....
Since the introduction of bone morphogenetic proteins, their use has become an invaluable ally for the treatment of …
Bone Tissue Engineering Strategies in Co-Delivery of Bone Morphogenetic Protein-2 and Biochemical Signaling Factors.
Kim S, et al. Adv Exp Med Biol 2018 - Review. PMID 30357626
Administration of bone morphogenetic protein-2 (BMP-2), which is commercially approved by the food and drug administration to damaged bone sites has been investigated for the purpose of bone tissue regeneration. ...To the end, this review summarizes the biological functions and synergistic effects of dual administration modalities involving BMP-2 as well as recent developments in bone tissue engineering applications....
Administration of bone morphogenetic protein-2 (BMP-2), which is commercially approved by the food and drug administ
Bone morphogenetic proteins and spinal fusion.
Walker DH and Wright NM. Neurosurg Focus 2002 - Review. PMID 15766229
Bone morphogenetic proteins (BMPs) have increasingly become a focus of research in the laboratory, with animal models, and in human clinical trials for the treatment of spinal disorders. ...Although few complications have been reported, BMPs can induce heterotopic bone formation, especially when placed adjacent to exposed neural elements. ...
Bone morphogenetic proteins (BMPs) have increasingly become a focus of research in the laboratory, with animal models,
Bone morphogenetic proteins. Development and clinical efficacy in the treatment of fractures and bone defects.
Termaat MF, et al. J Bone Joint Surg Am 2005 - Review. PMID 15930551
The discovery of bone morphogenetic proteins marks a major step forward in the understanding of bone physiology and in the development of advanced methods in skeletal surgery. ...The current clinical application of bone morphogenetic proteins is safe and efficacious as a result of a well-regulated cascade of events leading to bone formation. ...
The discovery of bone morphogenetic proteins marks a major step forward in the understanding of bone physiology …
The compositional and nano-structural basis of fracture healing in healthy and osteoporotic bone.
Mathavan N, et al. Sci Rep 2018. PMID 29371668 Free PMC article.
And how do pharmacological treatments, such as bone morphogenetic protein 7 (BMP-7) alone or synergistically combined with zoledronate (ZA), alter callus composition and nano-structure in such environments? ...ZA mitigated the effects of the upregulated catabolism induced by both BMP-7 and an osteoporotic bone environment. The findings contribute to our understanding of how the repair processes in healthy and osteoporotic bone differ in both untreated and treated contexts and the data presented represents the most comprehensive study of fracture healing at the nanoscale undertaken to date....
And how do pharmacological treatments, such as bone morphogenetic protein 7 (BMP-7) alone or synergistically combined with zol …
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