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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 6
1966 13
1967 19
1968 11
1969 17
1970 6
1971 13
1972 14
1973 9
1974 11
1975 12
1976 13
1977 15
1978 7
1979 8
1980 11
1981 8
1982 5
1983 8
1984 9
1985 7
1986 14
1987 10
1988 10
1989 13
1990 15
1991 19
1992 16
1993 38
1994 29
1995 33
1996 48
1997 36
1998 48
1999 63
2000 69
2001 57
2002 81
2003 119
2004 120
2005 165
2006 152
2007 167
2008 208
2009 253
2010 306
2011 313
2012 329
2013 364
2014 354
2015 397
2016 387
2017 447
2018 439
2019 247
2020 2
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4,833 results
Results by year
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Page 1
Effects of Local Drug and Chemical Compound Delivery on Bone Regeneration Around Dental Implants in Animal Models: A Systematic Review and Meta-Analysis.
Alenezi A, et al. Int J Oral Maxillofac Implants 2018 - Review. PMID 29340346
The search was limited to animal experiments using endosseous implants combined with local drug delivery systems. Meta-analyses were performed for the outcome bone-to-implant contact (BIC). ...There were two main methods for local drug delivery at the bone-implant interface: (1) directly from an implant surface by coating or immobilizing techniques, and (2) the local application of drugs to the implant site, using carriers. ...
The search was limited to animal experiments using endosseous implants combined with local drug delivery systems. Meta-analyses were …
Local and targeted drug delivery for bone regeneration.
Newman MR and Benoit DS. Curr Opin Biotechnol 2016 - Review. PMID 27064433 Free PMC article.
Alternatively, emulating the spatiotemporal cascade of endogenous factors through controlled drug delivery may provide superior bone regenerative approaches. ...These carriers, combined with osteoregenerative drugs and/or stimuli-sensitive linkers, may enhance bone regeneration while minimizing off-target tissue effects....
Alternatively, emulating the spatiotemporal cascade of endogenous factors through controlled drug delivery may provide superior bo
Osteoinduction of bone grafting materials for bone repair and regeneration.
García-Gareta E, et al. Bone 2015 - Review. PMID 26163110
Regeneration of bone defects caused by trauma, infection, tumours or inherent genetic disorders is a clinical challenge that usually necessitates bone grafting materials. Autologous bone or autograft is still considered the clinical "gold standard" and the most effective method for bone regeneration. ...
Regeneration of bone defects caused by trauma, infection, tumours or inherent genetic disorders is a clinical challenge that u
Effects of Hyaluronic Acid and Hydroxyapatite/Beta-tricalcium Phosphate in Combination on Bone Regeneration of a Critical-size Defect in an Experimental Model.
Diker N, et al. J Craniofac Surg 2018. PMID 29438204
The aim of this study was to evaluate the effects of HyA on bone regeneration in critical-size calvarial defects. Twenty-four female Sprague-Dawley rats were used in the present study. ...However, HyA alone was unable to induce sufficient bone regeneration compared with treatments involving graft materials (Graft and HyA + Graft). ...
The aim of this study was to evaluate the effects of HyA on bone regeneration in critical-size calvarial defects. Twent …
Parathyroid hormone for bone regeneration.
Wojda SJ and Donahue SW. J Orthop Res 2018 - Review. PMID 29926970 Free article.
The anabolic effect PTH has on bone has led to research on its use for bone regeneration applications. Numerous studies in animal models have indicated enhanced fracture healing as a result of once daily injections of PTH. ...This review briefly summarizes the unmet clinical need for improved bone regeneration techniques and how PTH may help fill that void by both systemically and locally delivered PTH for bone regeneration applications. © 2018 Orthopaedic Research Society. ...
The anabolic effect PTH has on bone has led to research on its use for bone regeneration applications. Numerous studies …
Evaluation of the effects of platelet-rich fibrin on bone regeneration in diabetic rabbits.
Durmuşlar MC, et al. J Craniomaxillofac Surg 2016. PMID 26732635
OBJECTIVES: This study aimed to investigate the effect of platelet-rich fibrin on bone regeneration in critical size defects in the calvaria of diabetic rabbits. ...Two bicortical circular defects 15 mm in diameter were created in the parietal bone of each animal. Each group was further divided into four groups: subgroup E, the defect was left empty; subgroup PRF, the defects were filled only with PRF; subgroup AB, the defects were filled with autogenous bone; subgroup AB + PRF, the defects were filled with autogenous bone combined with PRF. ...
OBJECTIVES: This study aimed to investigate the effect of platelet-rich fibrin on bone regeneration in critical size defects i …
Applications of Metals for Bone Regeneration.
Glenske K, et al. Int J Mol Sci 2018 - Review. PMID 29534546 Free PMC article.
The regeneration of bone tissue is the main purpose of most therapies in dental medicine. For bone regeneration, calcium phosphate (CaP)-based substitute materials based on natural (allo- and xenografts) and synthetic origins (alloplastic materials) are applied for guiding the regeneration processes. ...The present review focuses on frequently used metals as integral parts of materials designed for bone regeneration, with the aim to provide an overview of currently existing knowledge about the effects of metals in the field of bone regeneration....
The regeneration of bone tissue is the main purpose of most therapies in dental medicine. For bone regeneration, …
Effects of Enhanced Hydrophilic Titanium Dioxide-Coated Hydroxyapatite on Bone Regeneration in Rabbit Calvarial Defects.
Lee JE, et al. Int J Mol Sci 2018. PMID 30463215 Free PMC article.
The regeneration of bone defects caused by periodontal disease or trauma is an important goal. Porous hydroxyapatite (HA) is an osteoconductive graft material. ...The combination of TiO₂/HA and UV irradiation in bone regeneration appears to induce a favorable response....
The regeneration of bone defects caused by periodontal disease or trauma is an important goal. Porous hydroxyapatite (HA) is a …
Systemic drugs that influence titanium implant osseointegration
Apostu D, et al. Drug Metab Rev 2017 - Review. PMID 28030966
It is currently accepted that systemic pharmacological agents can either enhance or impair implant osseointegration; therefore, proper drug selection is essential. This review aims to discuss the varying effects of three different classes of treatments on improving this process....
It is currently accepted that systemic pharmacological agents can either enhance or impair implant osseointegration; therefore, proper dr
The roles of ions on bone regeneration.
O'Neill E, et al. Drug Discov Today 2018 - Review. PMID 29407177
Bone scientists are actively investigating a range of methods to promote skeletal tissue regeneration. A review of recent literature has revealed that several ions are uniquely capable of inducing stem cell differentiation down desired lineages. ...In this review, we highlight the developments in using ions in conjunction with biomaterials for bone regeneration....
Bone scientists are actively investigating a range of methods to promote skeletal tissue regeneration. A review of recent lite
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