"Bone Res"[Journal] - Search Results

Year	Number of Results
2013	30
2014	22
2015	21
2016	28
2017	31
2018	37
2019	36
2020	43
2021	52
2022	65
2023	65
2024	71
2025	105
2026	30

1

Factor VIII restores bone parameters and modulates muscle proteo-metabolome in Factor VIII knockout male mice.

Babuty A, Muñoz-Garcia J, Christophe OD, Fradet L, Taupin M, Cochonneau D, Ollivier E, Driessler F, Lange C, Boychenko O, Heymann MF, Heymann D. Babuty A, et al. Bone Res. 2026 Mar 11;14(1):30. doi: 10.1038/s41413-025-00485-2. Bone Res. 2026. PMID: 41813666 Free PMC article.

2

PRMT6 is required for initiating and amplifying macrophage-induced inflammation in heterotopic ossification by increasing CCL2 expression.

Chu W, Peng W, Wu Z, Xiong Y, Gao Z, Li Y, Zhang B, Wang L, Wang H, Han C, Lu X. Chu W, et al. Bone Res. 2026 Mar 10;14(1):29. doi: 10.1038/s41413-026-00512-w. Bone Res. 2026. PMID: 41803087 Free PMC article.

3

The spinal lymphatic system: an emerging pathway bridging fluid homeostasis, immunity, and disease.

Hou Y, Wu J, Yang S, Wang H, Wang X, Lu Z, Chen Z, Feng J, Wang H. Hou Y, et al. Bone Res. 2026 Mar 5;14(1):28. doi: 10.1038/s41413-026-00508-6. Bone Res. 2026. PMID: 41781379 Free PMC article. Review.

4

TGF-β-induced fibrotic scar formation limits recovery of spinal cord injury.

Pan D, Wu P, Noller K, Cahan P, Cao X. Pan D, et al. Bone Res. 2026 Feb 25;14(1):27. doi: 10.1038/s41413-026-00507-7. Bone Res. 2026. PMID: 41741406 Free PMC article.

5

Synovial inflammatory macrophage-derived extracellular vesicles exacerbate cartilage lesions with a FMRP-selectively sorted manner in osteoarthritis.

Zhao S, Wang J, Xue M, Wu B, Sheng L, Wen Y, Wang G, Song J, Du D, Xu J. Zhao S, et al. Bone Res. 2026 Feb 17;14(1):26. doi: 10.1038/s41413-025-00502-4. Bone Res. 2026. PMID: 41702879 Free PMC article.

6

HIF-1α and BMAL1 in bone regeneration: crosstalk between hypoxia response and circadian rhythm.

Weng Y, Xiong J, Zhao Q, Tan Z. Weng Y, et al. Bone Res. 2026 Feb 14;14(1):25. doi: 10.1038/s41413-026-00506-8. Bone Res. 2026. PMID: 41690951 Free PMC article. Review.

7

Smart biomaterials for skeletal aging repair and regeneration.

Liang D, Wang H, Jiang Y, Zhang Z, Zhou T, Ge S, Tan S, Qin K, Wang Y, Lin X, Xie Y, Lyu H, Zhang L. Liang D, et al. Bone Res. 2026 Feb 14;14(1):24. doi: 10.1038/s41413-026-00505-9. Bone Res. 2026. PMID: 41688434 Free PMC article. Review.

8

Estradiol regulates osteoclast sialylation via ST3Gal1 in postmenopausal osteoporosis.

Dou C, Dan Y, Zhang Z, Li X, Qu Y, Wu Y, Zhang Z, Guo S, Xu J, Luo F. Dou C, et al. Bone Res. 2026 Feb 12;14(1):22. doi: 10.1038/s41413-025-00498-x. Bone Res. 2026. PMID: 41680135 Free PMC article.

9

Advances in the mechanism for steroid-induced osteonecrosis of the femoral head.

Zhou R, Bian Y, Cai X, Sun H, Lv Z, Xu Y, Wang Y, Wang H, Zhu W, Feng B, Weng X. Zhou R, et al. Bone Res. 2026 Feb 12;14(1):23. doi: 10.1038/s41413-025-00477-2. Bone Res. 2026. PMID: 41680130 Free PMC article. Review.

10

Pharmacological HIF activation protects against diet-induced obesity, glucose intolerance, and skeletal dysfunction by exerting dual beneficial effects on energy metabolism and bone.

Valle-Tenney R, Peredo N, De Samblancx K, Nefyodova E, Cardoen R, Dehaemers T, Farlay D, Chapurlat R, Van der Schueren B, Mathieu C, Vangoitsenhoven R, Maes C. Valle-Tenney R, et al. Bone Res. 2026 Feb 11;14(1):21. doi: 10.1038/s41413-025-00503-3. Bone Res. 2026. PMID: 41667436 Free PMC article.

11

Modeling the chondrocyte-derived osteoblasts formation process reveals its molecular signature and regulation network.

Ruiz-Hernández R, Gay L, Moncho-Amor V, Martín P, Vergara-Arce JA, Di Blasio S, Snoeks T, Cossío U, Matheu A, Caffarel MM, Gerovska D, Araúzo-Bravo MJ, Vilas A, Prosper F, Moya S, Alonso-Alconada D, Alonso-Varona A, Nusspaumer G, Lopez-Rios J, Rizotti K, Lovell-Badge R, Bonnet D, Malanchi I, Abarrategi A. Ruiz-Hernández R, et al. Bone Res. 2026 Feb 9;14(1):19. doi: 10.1038/s41413-025-00500-6. Bone Res. 2026. PMID: 41663374 Free PMC article.

12

Sialin-STAT3 axis regulates bone homeostasis in mice.

Li X, Hu L, Xu Y, Wang X, Cao Z, Jiang O, Yao J, Liu M, Kong S, Wang J, Wang X, Wang S. Li X, et al. Bone Res. 2026 Feb 9;14(1):20. doi: 10.1038/s41413-025-00504-2. Bone Res. 2026. PMID: 41663362 Free PMC article.

13

Single cell atlas decodes the molecular dynamics of scar repair after human rotator cuff tear.

Qin Y, Yang G, Zhang T, Yang Y, Wan L, Zhang T, Wang L, Hu Z, Dai Z, Zhou H, Li C, Hu J, Lu H. Qin Y, et al. Bone Res. 2026 Feb 5;14(1):17. doi: 10.1038/s41413-025-00501-5. Bone Res. 2026. PMID: 41644521 Free PMC article.

14

Sulfated chitosan mitigates acute lung injury induced bone loss via immunoregulation.

Liu Y, Ji L, Zhu F, Yu J, Huang D, Cui J, Wang X, Wang J, Liu C. Liu Y, et al. Bone Res. 2026 Feb 5;14(1):18. doi: 10.1038/s41413-025-00475-4. Bone Res. 2026. PMID: 41644508 Free PMC article.

15

FOXI3 establishes the ectodermal niche in pharyngeal arches for cranial neural crest cells and their lineages.

Chen X, Wu S, Chen Y, Li C, Feng X, Fu Y, Zhu Y, Chen Y, Chen L, Yang R, Dai R, Zhang J, He A, Wang X, Ma D, Hao B, Zhang T, Ma J. Chen X, et al. Bone Res. 2026 Feb 4;14(1):16. doi: 10.1038/s41413-025-00499-w. Bone Res. 2026. PMID: 41639043 Free PMC article.

16

Microenvironmental stiffness directs microtubule perturbation in chondrocyte mitosis via ILK-refilinB/Smad3 axis.

Duan M, Zhou C, Su G, Zhang C, Ren J, Chi Q, Liu X, Yang L, Bai H, Zeng YC, Kim S, Zhai Y, Oh CY, Ye AY, Chen Y, Si L, Liu X, Xie J. Duan M, et al. Bone Res. 2026 Jan 30;14(1):15. doi: 10.1038/s41413-025-00491-4. Bone Res. 2026. PMID: 41617674 Free PMC article.

17

Tissue and extracellular matrix remodeling of the subchondral bone during osteoarthritis of knee joints as revealed by spatial mass spectrometry imaging.

Schurman CA, Bons J, Woo JJ, Yee C, Liu Q, Tao N, Alliston T, Angel P, Schilling B. Schurman CA, et al. Bone Res. 2026 Jan 26;14(1):14. doi: 10.1038/s41413-025-00495-0. Bone Res. 2026. PMID: 41587965 Free PMC article.

18

Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing.

Huang M, Balu AR, Molitoris KH, Bareja A, Baht GS. Huang M, et al. Bone Res. 2026 Jan 22;14(1):13. doi: 10.1038/s41413-025-00489-y. Bone Res. 2026. PMID: 41571629 Free PMC article.

19

PTH induced osteoblast Slit3 to decrease aberrant sensory innervation in degenerated vertebral endplates to relieve low back pain in mice.

Zhang W, Otte AD, Wang Z, Barik SK, Wan M, Cao X, Crane JL. Zhang W, et al. Bone Res. 2026 Jan 22;14(1):12. doi: 10.1038/s41413-025-00488-z. Bone Res. 2026. PMID: 41571628 Free PMC article.

20

Thrombospondin 1 and 2 regulate mesenchymal progenitor cell fate and matrix organization.

Hunter MK, Korlakunta S, Vishlaghi N, Mittal M, Cragg K, Juan C, Pagani CA, Sun Y, Lammlin L, Kessell K, Feist D, Choi JH, Hsieh ML, Saikia J, Duvall CL, Kang H, Alford AI, Hankenson KD, Tower RJ, Maerz T, Levi B. Hunter MK, et al. Bone Res. 2026 Jan 19;14(1):10. doi: 10.1038/s41413-025-00493-2. Bone Res. 2026. PMID: 41554713 Free PMC article.

21

Bone sialoprotein: a multifunctional regulator of bone remodelling and tumour progression.

Kottmann V, Drees P, Gercek E, Ritz U. Kottmann V, et al. Bone Res. 2026 Jan 19;14(1):11. doi: 10.1038/s41413-025-00490-5. Bone Res. 2026. PMID: 41554710 Free PMC article. Review.

22

The role of the lymphatic system in musculoskeletal system health and disease: research progress and future directions.

Luo Y, Song J, Zheng S, Sun J, Liu G, Xiao Z, Opoku M, Arthur Vithran DT, Zhou J, Xiao W, Li Y. Luo Y, et al. Bone Res. 2026 Jan 19;14(1):8. doi: 10.1038/s41413-025-00479-0. Bone Res. 2026. PMID: 41554698 Free PMC article. Review.

23

Neutrophil-initiated nociceptive ingrowth orchestrates inflammation resolution to potentiate bone regeneration.

Qi X, Yang G, Xu Z, Zhou M, Liu T, Du J, Lin S, Jiang X. Qi X, et al. Bone Res. 2026 Jan 19;14(1):9. doi: 10.1038/s41413-025-00481-6. Bone Res. 2026. PMID: 41554692 Free PMC article.

24

APEX1, a transcriptional hub for endochondral ossification and fracture repair.

Valdés-Fernández J, Echanove-González de Anleo M, Romero-Torrecilla JA, López-Martínez T, Ripalda-Cemboráin P, Calleja-Cervantes ME, Ullate-Agote A, Iglesias E, Prados-Pinto B, de la Pompa JL, Prósper F, Muiños-López E, Granero-Moltó F. Valdés-Fernández J, et al. Bone Res. 2026 Jan 16;14(1):7. doi: 10.1038/s41413-025-00486-1. Bone Res. 2026. PMID: 41545352 Free PMC article.

25

TGF-β/BMP signaling in skeletal biology: molecular mechanisms, regulatory networks, and therapeutic implications in development, regeneration, and disease.

Liao J, Wu T, Zhang Q, Shen P, Huang Z, Wang J, Zhang P, Lin S, Pi J, Zhang N, Wang H, Chen G. Liao J, et al. Bone Res. 2026 Jan 13;14(1):6. doi: 10.1038/s41413-025-00497-y. Bone Res. 2026. PMID: 41530114 Free PMC article. Review.

26

Progress on Omega-3 fatty acids for the comprehensive and targeted treatment of spinal cord injury.

Yuan Z, Shi L, Tao XN, Fan X, Zheng H, Shang Y, Zhao X, Yang F, Lin H, Xiao P, Chu B, Qiu J, Zong S, Ran N, Kong X, Sun JP, Zhou H, Feng S. Yuan Z, et al. Bone Res. 2026 Jan 12;14(1):3. doi: 10.1038/s41413-025-00461-w. Bone Res. 2026. PMID: 41521190 Free PMC article. Review.

27

Biologics for bone regeneration: advances in cell, protein, gene, and mRNA therapies.

Del Toro Runzer C, Balmayor ER, van Griensven M. Del Toro Runzer C, et al. Bone Res. 2026 Jan 12;14(1):5. doi: 10.1038/s41413-025-00487-0. Bone Res. 2026. PMID: 41521187 Free PMC article. Review.

28

Electric field stimulation-responsive hydrogels for bone regeneration: from mechanisms to applications.

Ouyang L, He X, Liao Y, Zhou X, Liao J, Lin Z, Xie X, Hu W, Zhang W, Al-Smadi F, Tao R, Cao F, Hu Y, Liu G, Mi B. Ouyang L, et al. Bone Res. 2026 Jan 12;14(1):4. doi: 10.1038/s41413-025-00482-5. Bone Res. 2026. PMID: 41521175 Free PMC article. Review.

29

The roles of the nerve-immune axis in modulating bone regeneration.

Zhao Y, Xu K, Wu K, Guo Z, Li H, Lin N, Ye Z, Huang X, Xu J, Huang D. Zhao Y, et al. Bone Res. 2026 Jan 5;14(1):2. doi: 10.1038/s41413-025-00476-3. Bone Res. 2026. PMID: 41486263 Free PMC article. Review.

30

Inflammatory bone loss and signaling pathways in periodontitis: mechanistic insights and emerging therapeutic strategies.

de Molon RS, Vernal R, Oliveira GE, Steffens JP, Ervolino E, Theodoro LH, van den Beucken JJJP, Tetradis S. de Molon RS, et al. Bone Res. 2026 Jan 3;14(1):1. doi: 10.1038/s41413-025-00478-1. Bone Res. 2026. PMID: 41484074 Free PMC article. Review.

31

Bibliometric and LDA analysis of extracellular vesicles in osteoarthritis.

Xie H, Zhao L, Kang L, Meng W, Tan J, Liao G. Xie H, et al. Bone Res. 2025 Dec 23;13(1):105. doi: 10.1038/s41413-025-00484-3. Bone Res. 2025. PMID: 41429775 Free PMC article. Review.

32

Osteoporosis and risk of dementia among older adults: a population‑based cohort study.

Wang J, Wang S, Jin C, Li X, Mo C, Zheng J, Lu X, Liang F, Gu D. Wang J, et al. Bone Res. 2025 Dec 22;13(1):104. doi: 10.1038/s41413-025-00480-7. Bone Res. 2025. PMID: 41423696 Free PMC article.

33

Pharmacological inhibition of RAS pathway alleviates spine deformity in a mouse model of neurofibromatosis type 1.

Kovaci F, Goachet C, Perrin S, Slimani L, Coulpier F, Tilotta F, Topilko P, Colnot C. Kovaci F, et al. Bone Res. 2025 Dec 16;13(1):103. doi: 10.1038/s41413-025-00492-3. Bone Res. 2025. PMID: 41397954 Free PMC article.

34

Neonatal bone marrow interstitial fluid supports expansion and osteogenic ability of human bone marrow mesenchymal stromal cells.

Zhang J, Ma T, Ke L, Zhang H, Hu J, Li S, Wang H, Meng A. Zhang J, et al. Bone Res. 2025 Dec 15;13(1):102. doi: 10.1038/s41413-025-00496-z. Bone Res. 2025. PMID: 41392038 Free PMC article.

35

Author Correction: Inhibition of cyclooxygenase-2 activity in subchondral bone modifies a subtype of osteoarthritis.

Tu M, Yang M, Yu N, Zhen G, Wan M, Liu W, Ji B, Ma H, Guo Q, Tong P, Cao L, Luo X, Cao X. Tu M, et al. Bone Res. 2025 Dec 8;13(1):101. doi: 10.1038/s41413-025-00443-y. Bone Res. 2025. PMID: 41360759 Free PMC article. No abstract available.

36

Human peripheral osteoclast-precursor-development patterns reveal the significance of RPS17-dependent ribosome synthesis to Ankylosing Spondylitis lesions.

Ke D, Dai H, Han J, Su Y, Zhu H, Zhang R, Gao T, Yang L, Yu Y, Bai X, Zhang C, Xu J. Ke D, et al. Bone Res. 2025 Dec 4;13(1):100. doi: 10.1038/s41413-025-00474-5. Bone Res. 2025. PMID: 41345114 Free PMC article.

37

Molecular mechanisms and therapeutic implications of the sympathetic nervous system in bone-related disorders: a brain-bone axis perspective.

Liu M, Liu Y, Yu J, Gong J, Zhao C, Liu Z. Liu M, et al. Bone Res. 2025 Dec 2;13(1):98. doi: 10.1038/s41413-025-00494-1. Bone Res. 2025. PMID: 41326350 Free PMC article. Review.

38

Weight loss induced bone loss: mechanism of action and clinical implications.

Liu H, Li B, Liu L, Ying W, Rosen CJ. Liu H, et al. Bone Res. 2025 Dec 2;13(1):99. doi: 10.1038/s41413-025-00483-4. Bone Res. 2025. PMID: 41326347 Free PMC article. Review.

39

SMN deficiency inhibits endochondral ossification via promoting TRAF6-induced ubiquitination degradation of YBX1 in spinal muscular atrophy.

Zhou Z, Fan X, Xiang T, Suo Y, Shi X, Li Y, Hua Y, Sheng L, Zhou X. Zhou Z, et al. Bone Res. 2025 Dec 1;13(1):97. doi: 10.1038/s41413-025-00473-6. Bone Res. 2025. PMID: 41320719 Free PMC article.

40

Biomaterial-mediated macrophage polarization remodeling and sequential regulation: a potential strategy in bone infections treatment.

Shi X, Xu C, Chen Z, Li M, Yin Z, Wang B, Li Y, Wu Y, Wu X, Xu Y. Shi X, et al. Bone Res. 2025 Nov 25;13(1):96. doi: 10.1038/s41413-025-00471-8. Bone Res. 2025. PMID: 41290567 Free PMC article. Review.

41

Bioaugmented osteosynthesis: precise monitoring and intervention of the bone healing microenvironment.

Xu G, Chen J, Xiao Z, Xu J, Zhang L, Tang P. Xu G, et al. Bone Res. 2025 Nov 25;13(1):95. doi: 10.1038/s41413-025-00466-5. Bone Res. 2025. PMID: 41285741 Free PMC article.

42

Single-cell sequencing reveals a senescent immune landscape in bone marrow lesions inducing articular cartilage damage in osteoarthritis.

Lou P, Lu X, Li M, Yao Y, Shao X, Shou D, Fan X, Tong P, Zhang Y. Lou P, et al. Bone Res. 2025 Nov 21;13(1):94. doi: 10.1038/s41413-025-00467-4. Bone Res. 2025. PMID: 41272390 Free PMC article.

43

Sirtuin 5-mediated desuccinylation of Slc25a4 inhibits osteoporosis by enhancing mitochondrial respiration.

Chen J, Jiang X. Chen J, et al. Bone Res. 2025 Nov 17;13(1):93. doi: 10.1038/s41413-025-00464-7. Bone Res. 2025. PMID: 41243032 Free PMC article.

44

Descendants of hypertrophic chondrocytes promote angiogenesis by secreting THBS4 during bone growth and injury repair.

Song S, Fan J, Ding G, Yin J, Lu W, Huang L, Hu J, Gong X, Gao B, Jie Q, Cheah KSE, Zheng C, Yang L. Song S, et al. Bone Res. 2025 Nov 10;13(1):92. doi: 10.1038/s41413-025-00469-2. Bone Res. 2025. PMID: 41207902 Free PMC article.

45

Galactose-modified small molecule modulator targets RORα to enhance circadian rhythm and alleviate periodontitis-associated alveolar bone loss.

Feng G, Liao Z, Wang Y, Tang Q, Li N, Li C, Liu Y, Liu R, Cui M, Fan W, Yin Y, Meng L, Zeng J, Chen Z, Luo G, Xiang P, Wan Q, Chen L. Feng G, et al. Bone Res. 2025 Oct 30;13(1):91. doi: 10.1038/s41413-025-00445-w. Bone Res. 2025. PMID: 41168164 Free PMC article.

46

The relationship between OPLL and metabolic disorders.

Wang J, Wei Z, Kong Q, Sun Y, Zhang Z, Yang H, Chen X. Wang J, et al. Bone Res. 2025 Oct 24;13(1):90. doi: 10.1038/s41413-025-00446-9. Bone Res. 2025. PMID: 41136389 Free PMC article. Review.

47

What a pain in the back: etiology, diagnosis and future treatment directions for discogenic low back pain.

Kaneda G, Zila L, Wechsler JT, Shafi K, Cheema K, Bae H, Kim SD, Tuchman A, Li D, Sheyn D. Kaneda G, et al. Bone Res. 2025 Oct 21;13(1):89. doi: 10.1038/s41413-025-00472-7. Bone Res. 2025. PMID: 41120264 Free PMC article. Review.

48

Pak4-mediated crosstalk between necroptotic macrophages and tendon stem/progenitor cells contributes to traumatic heterotopic ossification formation.

Sun Z, Liu H, Xu Y, Chen Q, Luo G, Yuan Z, Chen Z, He K, Fan C, Li J, Ruan H. Sun Z, et al. Bone Res. 2025 Oct 20;13(1):88. doi: 10.1038/s41413-025-00463-8. Bone Res. 2025. PMID: 41111094 Free PMC article.

49

Author Correction: Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12.

Lin C, Liu L, Zeng C, Cui ZK, Chen Y, Lai P, Wang H, Shao Y, Zhang H, Zhang R, Zhao C, Fang H, Cai D, Bai X. Lin C, et al. Bone Res. 2025 Oct 17;13(1):87. doi: 10.1038/s41413-025-00462-9. Bone Res. 2025. PMID: 41102139 Free PMC article. No abstract available.

50

Cytosolic phospholipase A2 as a therapeutic target for degenerative joint diseases.

Huang G, He C, Fu W, Bi J, Wang J, Wiznia DH, Liu CJ. Huang G, et al. Bone Res. 2025 Oct 15;13(1):86. doi: 10.1038/s41413-025-00470-9. Bone Res. 2025. PMID: 41093854 Free PMC article.

51

Intelligent microstructure materials for diagnosis and treatment of osteoarthritis: progress and AI-enpowered future.

Gao W, Zhong J, Liu X, Bai D, Wu M. Gao W, et al. Bone Res. 2025 Oct 15;13(1):85. doi: 10.1038/s41413-025-00458-5. Bone Res. 2025. PMID: 41093836 Free PMC article. Review.

52

Aging microenvironment in osteoarthritis focusing on early-stage alterations and targeted therapies.

Dang Y, Liu Y, Zhang B, Zhang X. Dang Y, et al. Bone Res. 2025 Oct 10;13(1):84. doi: 10.1038/s41413-025-00465-6. Bone Res. 2025. PMID: 41073390 Free PMC article. Review.

53

Injured bone-triggered osteokines secretion promotes diabetic wound healing.

Shen T, Dai K, Zhang S, Wang J, Liu C. Shen T, et al. Bone Res. 2025 Oct 2;13(1):83. doi: 10.1038/s41413-025-00454-9. Bone Res. 2025. PMID: 41038809 Free PMC article.

54

Author Correction: Synovial fibroblast derived small extracellular vesicles miRNA15-29148 promotes articular chondrocyte apoptosis in rheumatoid arthritis.

Zhang Z, Liu L, Ti H, Chen M, Chen Y, Du D, Zhan W, Wang T, Wu X, Wu J, Mao D, Yuan Z, Ruan J, Rong G, Yuan FL. Zhang Z, et al. Bone Res. 2025 Sep 30;13(1):82. doi: 10.1038/s41413-025-00468-3. Bone Res. 2025. PMID: 41028739 Free PMC article. No abstract available.

55

Unraveling the mechanisms of bone diseases: targeting dendritic cells in osteoimmunology for internal homeostasis balance.

Chen Y, Wang S, Chen X, Wu Z, He F, Chen Q. Chen Y, et al. Bone Res. 2025 Sep 28;13(1):81. doi: 10.1038/s41413-025-00456-7. Bone Res. 2025. PMID: 41015585 Free PMC article. Review.

56

Nuclear FGF2 orchestrates phase separation-mediated rDNA chromatin architecture to control BMSCs cell fate.

Zhang H, Wang Z, Liu Z, Li X, Sun W, Zhen W, Xu F, Wang R, Yin Q, Cao S, Wu M, He J, Xu J, Li Y, Yuan Q. Zhang H, et al. Bone Res. 2025 Sep 24;13(1):80. doi: 10.1038/s41413-025-00451-y. Bone Res. 2025. PMID: 40993129 Free PMC article.

57

Mechanism of Piezo1 regulating chondrocyte mitochondrial function and promoting fracture healing through β-catenin/LARS2 signaling pathway.

Zhang T, Lv H, Jia S, Wang L, Liu W, Ding K, Du X, Hou G, Hou Z, Zhang Y, Zou W, Chen W, Zhu Y. Zhang T, et al. Bone Res. 2025 Sep 24;13(1):79. doi: 10.1038/s41413-025-00459-4. Bone Res. 2025. PMID: 40993116 Free PMC article.

58

Research progress on sarcopenia in the musculoskeletal system.

Mao X, Lv K, Qi W, Cheng W, Li T, Sun Y, Jin H, Pan H, Wang D. Mao X, et al. Bone Res. 2025 Sep 23;13(1):78. doi: 10.1038/s41413-025-00455-8. Bone Res. 2025. PMID: 40987776 Free PMC article. Review.

59

The impact of mitochondrial dysfunction on osteoarthritis cartilage: current insights and emerging mitochondria-targeted therapies.

Tan S, Sun Y, Li S, Wu H, Ding Y. Tan S, et al. Bone Res. 2025 Sep 1;13(1):77. doi: 10.1038/s41413-025-00460-x. Bone Res. 2025. PMID: 40887466 Free PMC article. Review.

60

The role of the unfolded protein response pathway in bone homeostasis and potential therapeutic target in cancer-associated bone disease.

Muehlebach ME, Holstein SA. Muehlebach ME, et al. Bone Res. 2025 Aug 28;13(1):76. doi: 10.1038/s41413-025-00457-6. Bone Res. 2025. PMID: 40877255 Free PMC article. Review.

61

Association between osteoporosis and rotator cuff tears: evidence from causal inference and colocalization analyses.

Liu Y, Zhao R, Huang Z, Li F, Li X, Zhou K, Derwin KA, Zheng X, Cai H, Ma J. Liu Y, et al. Bone Res. 2025 Aug 28;13(1):75. doi: 10.1038/s41413-025-00450-z. Bone Res. 2025. PMID: 40866365 Free PMC article.

62

Chemotherapeutic drug-triggered AEP-cleaved G3BP1 orchestrates stress granules/nucleoli/mitochondria in osteosarcoma.

Shi Z, Zhao J, Lv Q, Liao K, Cao L, Yang J, Wang M, Zhou L, Xu H, Ge J, Qiu Y, Chen J, Chen J, Ma C, Lin Y. Shi Z, et al. Bone Res. 2025 Aug 26;13(1):74. doi: 10.1038/s41413-025-00453-w. Bone Res. 2025. PMID: 40858563 Free PMC article.

63

Osteocytic vinculin controls bone mass by modulating Mef2c-driven sclerostin expression in mice.

Wang Y, Huang J, Lin S, Qin L, Hao D, Zhang P, Huo S, Zou X, Chen D, Xiao G. Wang Y, et al. Bone Res. 2025 Aug 13;13(1):73. doi: 10.1038/s41413-025-00452-x. Bone Res. 2025. PMID: 40796727 Free PMC article.

64

The mitochondrial E3 ligase MAPL SUMOylates Drp1 to facilitate mitochondrial fission in intervertebral disc degeneration.

Lin Z, Lu X, Xu G, Song J, Wang H, Xia X, Lu F, Jiang J, Zhu W, Yu Z, Ma X, Zou F. Lin Z, et al. Bone Res. 2025 Aug 12;13(1):72. doi: 10.1038/s41413-025-00449-6. Bone Res. 2025. PMID: 40796734 Free PMC article.

65

Nucleic acid aptamers in orthopedic diseases: promising therapeutic agents for bone disorders.

He Z, Peng Q, Bin W, Zhao L, Chen Y, Zhang Y, Yang W, Yan X, Liu H. He Z, et al. Bone Res. 2025 Jul 24;13(1):71. doi: 10.1038/s41413-025-00447-8. Bone Res. 2025. PMID: 40707473 Free PMC article. Review.

66

Osteoclast-independent osteocyte dendrite defects in mice bearing the osteogenesis imperfecta-causing Sp7 R342C mutation.

Wang JS, Strauss K, Houghton C, Islam N, Yoon SH, Kobayashi T, Brooks DJ, Bouxsein ML, Zhao Y, Yee CS, Alliston TN, Wein MN. Wang JS, et al. Bone Res. 2025 Jul 19;13(1):70. doi: 10.1038/s41413-025-00440-1. Bone Res. 2025. PMID: 40683889 Free PMC article.

67

Single-cell transcriptomic analysis identifies systemic immunosuppressive myeloid cells and local monocytes/macrophages as key regulators in polytrauma-induced immune dysregulation.

Maniar D, Keenum MC, Vantucci CE, Guyer T, Chatterjee P, Leguineche K, Cheung K, Guldberg RE, Roy K. Maniar D, et al. Bone Res. 2025 Jul 7;13(1):69. doi: 10.1038/s41413-025-00444-x. Bone Res. 2025. PMID: 40623986 Free PMC article.

68

Cellular senescence and other age-related mechanisms in skeletal diseases.

Li K, Hu S, Chen H. Li K, et al. Bone Res. 2025 Jul 7;13(1):68. doi: 10.1038/s41413-025-00448-7. Bone Res. 2025. PMID: 40623977 Free PMC article. Review.

69

Reduced somatosensory innervation alters the skeletal transcriptome at a single cell level in a mouse model of type 2 diabetes.

Cherief M, Gomez-Salazar M, Kang M, Lee S, Ramesh S, Qin Q, Xu M, Kim S, Archer M, Zhu M, Hoke A, James AW. Cherief M, et al. Bone Res. 2025 Jul 4;13(1):67. doi: 10.1038/s41413-025-00436-x. Bone Res. 2025. PMID: 40615376 Free PMC article.

70

ER-induced PERK/TFEB cascade sequentially modulates mitochondrial dynamics during cranial suture expansion.

Cai J, Min Z, Li C, Zhao Z, Liu J, Jing D. Cai J, et al. Bone Res. 2025 Jun 23;13(1):66. doi: 10.1038/s41413-025-00427-y. Bone Res. 2025. PMID: 40550802 Free PMC article.

71

Membrane-initiated estrogen receptor-α signaling in osteoblasts is crucial for normal regulation of the cortical bone in female mice.

Jiang Y, Horkeby K, Henning P, Wu J, Nilsson KH, Lawenius L, Movérare-Skrtic S, Gupta P, Engdahl C, Koskela A, Tuukkanen J, Li L, Ohlsson C, Lagerquist MK. Jiang Y, et al. Bone Res. 2025 Jun 17;13(1):65. doi: 10.1038/s41413-025-00439-8. Bone Res. 2025. PMID: 40523885 Free PMC article.

72

Pathophysiology of Myopenia in rheumatoid arthritis.

Jin H, Wang G, Lu Q, Rawlins J, Chen J, Kashyap S, Charlesworth O, Xu D, Dai L, Zhu S, Xu J. Jin H, et al. Bone Res. 2025 Jun 16;13(1):64. doi: 10.1038/s41413-025-00438-9. Bone Res. 2025. PMID: 40523898 Free PMC article. Review.

73

Different role of the gut microbiota in postmenopausal and senile osteoporosis.

Zheng XQ, Guan ZY, Zhang YD, Song CL. Zheng XQ, et al. Bone Res. 2025 Jun 13;13(1):63. doi: 10.1038/s41413-025-00432-1. Bone Res. 2025. PMID: 40514392 Free PMC article. No abstract available.

74

Synovial fibroblast derived small extracellular vesicles miRNA15-29148 promotes articular chondrocyte apoptosis in rheumatoid arthritis.

Zhang Z, Liu L, Ti H, Chen M, Chen Y, Du D, Zhan W, Wang T, Wu X, Wu J, Mao D, Yuan Z, Ruan J, Rong G, Yuan FL. Zhang Z, et al. Bone Res. 2025 Jun 12;13(1):61. doi: 10.1038/s41413-025-00430-3. Bone Res. 2025. PMID: 40506465 Free PMC article.

75

Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration.

Cheng Z, Gao H, Shi P, Zhang A, Chen X, Chen Y, Gan W, Zhao K, Li S, Yang C, Zhang Y. Cheng Z, et al. Bone Res. 2025 Jun 12;13(1):62. doi: 10.1038/s41413-025-00441-0. Bone Res. 2025. PMID: 40506462 Free PMC article.

76

Inflammatory macrophage-derived itaconate inhibits DNA demethylase TET2 to prevent excessive osteoclast activation in rheumatoid arthritis.

Rong K, Wang D, Pu X, Zhang C, Zhang P, Cao X, Zheng J, Yang X, Liu K, Shi L, Li Y, Ma P, Ye D, Zhao J, Wang P, Qin A. Rong K, et al. Bone Res. 2025 Jun 11;13(1):60. doi: 10.1038/s41413-025-00437-w. Bone Res. 2025. PMID: 40500265 Free PMC article.

77

Current cutting-edge omics techniques on musculoskeletal tissues and diseases.

Li X, Fang L, Zhou R, Yao L, Clayton SW, Muscat S, Kamm DR, Wang C, Liu CJ, Qin L, Tower RJ, Karner CM, Guilak F, Tang SY, Loiselle AE, Meyer GA, Shen J. Li X, et al. Bone Res. 2025 Jun 9;13(1):59. doi: 10.1038/s41413-025-00442-z. Bone Res. 2025. PMID: 40484858 Free PMC article. Review.

78

AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition.

Kong K, Liu L, Zhang R, Chang Y, Shao Y, Zhao C, Qiao H, Jin M, Chen X, Shi W, Wu X, Fan W, Hu Y, Rong K, Zhang P, Li B, Zhang J, Ma P, Zhang X, Li H, Zhai Z. Kong K, et al. Bone Res. 2025 Jun 3;13(1):58. doi: 10.1038/s41413-025-00431-2. Bone Res. 2025. PMID: 40461512 Free PMC article.

79

RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth.

Hallett SA, Dixon A, Marrale I, Batoon L, Brenes J, Zhou A, Arbiv A, Kaartinen V, Allen B, Ono W, Franceschi RT, Ono N. Hallett SA, et al. Bone Res. 2025 May 29;13(1):57. doi: 10.1038/s41413-025-00426-z. Bone Res. 2025. PMID: 40442075 Free PMC article.

80

Mouse model of anti-RANKL discontinuation reveals reduced bone mass and quality through disruption of bone remodeling.

Ishikawa K, Tani S, Sakai N, Kudo Y, Horiuchi H, Kimura-Suda H, Takami M, Tsuji M, Inagaki K, Kiuchi Y, Negishi-Koga T. Ishikawa K, et al. Bone Res. 2025 May 28;13(1):56. doi: 10.1038/s41413-025-00433-0. Bone Res. 2025. PMID: 40425548 Free PMC article.

81

Age- and sex-specific deterioration on bone and osteocyte lacuno-canalicular network in a mouse model of premature aging.

Yılmaz D, Marques FC, Gregorio L, Schlatter J, Gehre C, Pararajasingam T, Qiu W, Mathavan N, Qin XH, Wehrle E, Kuhn GA, Müller R. Yılmaz D, et al. Bone Res. 2025 May 23;13(1):55. doi: 10.1038/s41413-025-00428-x. Bone Res. 2025. PMID: 40410139 Free PMC article.

82

Advances in spatial transcriptomics and its application in the musculoskeletal system.

Wang H, Cheng P, Wang J, Lv H, Han J, Hou Z, Xu R, Chen W. Wang H, et al. Bone Res. 2025 May 16;13(1):54. doi: 10.1038/s41413-025-00429-w. Bone Res. 2025. PMID: 40379648 Free PMC article. Review.

83

PTPN11 in cartilage development, adult homeostasis, and diseases.

Yang W, Lefebvre V. Yang W, et al. Bone Res. 2025 May 16;13(1):53. doi: 10.1038/s41413-025-00425-0. Bone Res. 2025. PMID: 40379623 Free PMC article. Review.

84

Biased agonism of G protein-coupled receptors as a novel strategy for osteoarthritis therapy.

Meng X, Qin L, Wang X. Meng X, et al. Bone Res. 2025 May 12;13(1):52. doi: 10.1038/s41413-025-00435-y. Bone Res. 2025. PMID: 40355428 Free PMC article. Review.

85

IGF2BP3-mediated m⁶A modification of RASGRF1 promoting joint injury in rheumatoid arthritis.

Geng Q, Jiao Y, Diao W, Xu J, Wang Z, Wang X, Wang Z, Zhao L, Yang L, Wang Y, Deng T, Wang B, Xiao C. Geng Q, et al. Bone Res. 2025 May 12;13(1):51. doi: 10.1038/s41413-025-00434-z. Bone Res. 2025. PMID: 40355406 Free PMC article.

86

Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice.

Ramteke P, Watson B, Toci M, Tran VA, Johnston S, Tsingas M, Barve RA, Mitra R, Loeser RF, Collins JA, Risbud MV. Ramteke P, et al. Bone Res. 2025 May 8;13(1):50. doi: 10.1038/s41413-025-00422-3. Bone Res. 2025. PMID: 40335469 Free PMC article.

87

Bone-derived factors mediate crosstalk between skeletal and extra-skeletal organs.

He T, Qin L, Chen S, Huo S, Li J, Zhang F, Yi W, Mei Y, Xiao G. He T, et al. Bone Res. 2025 Apr 30;13(1):49. doi: 10.1038/s41413-025-00424-1. Bone Res. 2025. PMID: 40307216 Free PMC article. Review.

88

Advancing osteoarthritis research: the role of AI in clinical, imaging and omics fields.

Ou J, Zhang J, Alswadeh M, Zhu Z, Tang J, Sang H, Lu K. Ou J, et al. Bone Res. 2025 Apr 22;13(1):48. doi: 10.1038/s41413-025-00423-2. Bone Res. 2025. PMID: 40263261 Free PMC article. Review.

89

SPI1 activates mitochondrial unfolded response signaling to inhibit chondrocyte senescence and relieves osteoarthritis.

Zu X, Chen S, Li Z, Hao L, Fu W, Zhang H, Yin Z, Wang Y, Wang J. Zu X, et al. Bone Res. 2025 Apr 14;13(1):47. doi: 10.1038/s41413-025-00421-4. Bone Res. 2025. PMID: 40229258 Free PMC article.

90

NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling.

Yuan H, Wang X, Du S, Li M, Zhu E, Zhou J, Dong Y, Wang S, Shan L, Liu Q, Wang B. Yuan H, et al. Bone Res. 2025 Apr 11;13(1):46. doi: 10.1038/s41413-025-00420-5. Bone Res. 2025. PMID: 40210857 Free PMC article.

91

Cell communication and relevant signaling pathways in osteogenesis-angiogenesis coupling.

Li S, Cai X, Guo J, Li X, Li W, Liu Y, Qi M. Li S, et al. Bone Res. 2025 Apr 7;13(1):45. doi: 10.1038/s41413-025-00417-0. Bone Res. 2025. PMID: 40195313 Free PMC article. Review.

92

Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies.

Dreyer TJ, Keen JAC, Wells LM, Hopkinson M, Orriss IR, Holdsworth G, Pitsillides AA, Roberts SJ. Dreyer TJ, et al. Bone Res. 2025 Apr 7;13(1):44. doi: 10.1038/s41413-025-00406-3. Bone Res. 2025. PMID: 40189599 Free PMC article.

93

KIAA1199 (CEMIP) regulates adipogenesis and whole-body energy metabolism.

Chen L, Shi K, Ditzel N, Qiu W, Tencerova M, Nielsen LHD, Figeac F, Rauch A, Liu Y, Tao J, Sramkova V, Rossmeislova L, Kerckhofs G, Parac-Vogt TN, de Bournonville S, Andersen TL, Rydén M, Kassem M. Chen L, et al. Bone Res. 2025 Apr 2;13(1):43. doi: 10.1038/s41413-025-00415-2. Bone Res. 2025. PMID: 40169533 Free PMC article.

94

M2 macrophages-derived exosomes for osteonecrosis of femoral head treatment: modulating neutrophil extracellular traps formation and endothelial phenotype transition.

Liu G, Cao R, Liu Q, Li H, Yan P, Wang K, Tian R, Yang P. Liu G, et al. Bone Res. 2025 Apr 1;13(1):42. doi: 10.1038/s41413-025-00412-5. Bone Res. 2025. PMID: 40169566 Free PMC article.

95

Callus organoids reveal distinct cartilage to bone transition mechanisms across donors and a role for biological sex.

Decoene I, Svitina H, Hamed MB, Economou A, Stegen S, Luyten FP, Papantoniou I. Decoene I, et al. Bone Res. 2025 Mar 26;13(1):41. doi: 10.1038/s41413-025-00418-z. Bone Res. 2025. PMID: 40140357 Free PMC article.

96

Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation.

Park S, Yoon K, Hong E, Kim MW, Kang MG, Mizuno S, Kim HJ, Lee MJ, Choi HJ, Heo JS, Bae JB, An H, Park N, Park H, Kim P, Son M, Pang K, Park JY, Takahashi S, Kwon YJ, Kang DW, Kim SJ. Park S, et al. Bone Res. 2025 Mar 24;13(1):40. doi: 10.1038/s41413-025-00419-y. Bone Res. 2025. PMID: 40128226 Free PMC article.

97

Bone marrow adipogenic lineage precursors are the major regulator of bone resorption in adult mice.

Lu J, He Q, Wang H, Yao L, Duffy M, Guo H, Braun C, Zhou Y, Liang Q, Lin Y, Bandyopadhyay S, Tan K, Choi Y, Liu XS, Qin L. Lu J, et al. Bone Res. 2025 Mar 19;13(1):39. doi: 10.1038/s41413-025-00405-4. Bone Res. 2025. PMID: 40102423 Free PMC article.

98

Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration.

Chen X, Zhou Y, Yao W, Gao C, Sha Z, Yi J, Wang J, Liu X, Dai C, Zhang Y, Wu Z, Yao X, Zhou J, Liu H, Chen Y, Ouyang H. Chen X, et al. Bone Res. 2025 Mar 17;13(1):37. doi: 10.1038/s41413-025-00411-6. Bone Res. 2025. PMID: 40097410 Free PMC article.

99

Bone-brain interaction: mechanisms and potential intervention strategies of biomaterials.

Yu J, Ji L, Liu Y, Wang X, Wang J, Liu C. Yu J, et al. Bone Res. 2025 Mar 17;13(1):38. doi: 10.1038/s41413-025-00404-5. Bone Res. 2025. PMID: 40097409 Free PMC article. Review.

100

SIRT3-PINK1-PKM2 axis prevents osteoarthritis via mitochondrial renewal and metabolic switch.

Deng Y, Hou M, Wu Y, Liu Y, Xia X, Yu C, Yu J, Yang H, Zhang Y, Zhu X. Deng Y, et al. Bone Res. 2025 Mar 14;13(1):36. doi: 10.1038/s41413-025-00413-4. Bone Res. 2025. PMID: 40087281 Free PMC article.

101

Reprogramming to restore youthful epigenetics of senescent nucleus pulposus cells for mitigating intervertebral disc degeneration and alleviating low back pain.

Ma W, Wang W, Zhao L, Fan J, Liu L, Huang L, Peng B, Wang J, Xu B, Liu H, Wu D, Zheng Z. Ma W, et al. Bone Res. 2025 Mar 12;13(1):35. doi: 10.1038/s41413-025-00416-1. Bone Res. 2025. PMID: 40075068 Free PMC article.

102

Characterizing a new rat model of chronic pain after spine surgery.

Wu Q, Ford NC, He S, Zhang C, Cui X, Liu J, Chen X, Cao X, Guan Y, Zang L. Wu Q, et al. Bone Res. 2025 Mar 12;13(1):34. doi: 10.1038/s41413-025-00408-1. Bone Res. 2025. PMID: 40074742 Free PMC article.

103

LATS1-modulated ZBTB20 perturbing cartilage matrix homeostasis contributes to early-stage osteoarthritis.

Hao X, Zhao J, Jia L, Ding G, Liang X, Su F, Yang S, Yang Y, Fan J, Zhang WJ, Yang L, Jie Q. Hao X, et al. Bone Res. 2025 Mar 12;13(1):33. doi: 10.1038/s41413-025-00414-3. Bone Res. 2025. PMID: 40069162 Free PMC article.

104

Beclin 1 of megakaryocytic lineage cells is locally dispensable for platelet hemostasis but functions distally in bone homeostasis.

Li L, Zhao C, Zhang R, Wei W, Liu B, Dong J, Gao X, Zhang D, Wang X, Lu M, Zhang Y, Yu Y, Yuan N, Xu Y, Wang J, Fang Y. Li L, et al. Bone Res. 2025 Mar 3;13(1):32. doi: 10.1038/s41413-025-00410-7. Bone Res. 2025. PMID: 40032858 Free PMC article.

105

Apolipoprotein E is a marker of all chondrocytes in the growth plate resting zone.

Kodama J, Oichi T, Wilkinson KJ, Abzug JM, Kaito T, Enomoto-Iwamoto M, Iwamoto M, Otsuru S. Kodama J, et al. Bone Res. 2025 Mar 3;13(1):31. doi: 10.1038/s41413-025-00407-2. Bone Res. 2025. PMID: 40025030 Free PMC article.

106

CD47 is required for mesenchymal progenitor proliferation and fracture repair.

Zondervan RL, Capobianco CA, Jenkins DC, Reicha JD, Fredrick L, Lam C, Schmanski JT, Isenberg JS, Ahn J, Marcucio RS, Hankenson KD. Zondervan RL, et al. Bone Res. 2025 Mar 3;13(1):29. doi: 10.1038/s41413-025-00409-0. Bone Res. 2025. PMID: 40025005 Free PMC article.

107

Enhanced SIRT3 expression restores mitochondrial quality control mechanism to reverse osteogenic impairment in type 2 diabetes mellitus.

Xian Y, Liu B, Shen T, Yang L, Peng R, Shen H, An X, Wang Y, Ben Y, Jiang Q, Guo B. Xian Y, et al. Bone Res. 2025 Mar 3;13(1):30. doi: 10.1038/s41413-024-00399-5. Bone Res. 2025. PMID: 40025004 Free PMC article.

108

Iron homeostasis and ferroptosis in muscle diseases and disorders: mechanisms and therapeutic prospects.

Ru Q, Li Y, Zhang X, Chen L, Wu Y, Min J, Wang F. Ru Q, et al. Bone Res. 2025 Feb 25;13(1):27. doi: 10.1038/s41413-024-00398-6. Bone Res. 2025. PMID: 40000618 Free PMC article. Review.

109

Bifidobacterium animalis subsp. lactis A6 ameliorates bone and muscle loss via modulating gut microbiota composition and enhancing butyrate production.

Chen M, Li Y, Zhai Z, Wang H, Lin Y, Chang F, Ge S, Sun X, Wei W, Wang D, Zhang M, Chen R, Yu H, Feng T, Huang X, Cheng D, Liu J, Di W, Hao Y, Yin P, Tang P. Chen M, et al. Bone Res. 2025 Feb 25;13(1):28. doi: 10.1038/s41413-024-00381-1. Bone Res. 2025. PMID: 40000617 Free PMC article.

110

Targeting AKT as a promising strategy for SOX2-positive, chemoresistant osteosarcoma.

Liu Y, Kang L, Luo J, Yang M, Wang D, Ye J, Yang X, Wan W, Wong J, Xiao J. Liu Y, et al. Bone Res. 2025 Feb 24;13(1):25. doi: 10.1038/s41413-024-00395-9. Bone Res. 2025. PMID: 39994220 Free PMC article.

111

CCN2 mediates fibroblast-macrophage interaction in knee arthrofibrosis based on single-cell RNA-seq analysis.

Li Z, Jiang J, Cai K, Qiao Y, Zhang X, Wang L, Kang Y, Wu X, Zhao B, Wang X, Zhang T, Lin Z, Wu J, Lu S, Gao H, Jin H, Xu C, Huangfu X, James Z, Chen Q, Zheng X, Liu NN, Zhao J. Li Z, et al. Bone Res. 2025 Feb 24;13(1):26. doi: 10.1038/s41413-025-00400-9. Bone Res. 2025. PMID: 39994205 Free PMC article.

112

3D imaging reveals changes in the neurovascular architecture of the murine calvarium with aging.

Horenberg AL, Ren Y, Zeng EZ, Rindone AN, Pathak AP, Grayson WL. Horenberg AL, et al. Bone Res. 2025 Feb 21;13(1):24. doi: 10.1038/s41413-025-00401-8. Bone Res. 2025. PMID: 39984434 Free PMC article.

113

Photothermal sensitive nanocomposite hydrogel for infectious bone defects.

Wu Y, Xie X, Luo G, Xie J, Ye X, Gu W, Mo A, Qian Z, Zhou C, Liao J. Wu Y, et al. Bone Res. 2025 Feb 14;13(1):22. doi: 10.1038/s41413-024-00377-x. Bone Res. 2025. PMID: 39952965 Free PMC article.

114

Matrix stiffness regulates nucleus pulposus cell glycolysis by MRTF-A-dependent mechanotransduction.

Xu H, Wei K, Ni J, Deng X, Wang Y, Xiang T, Song F, Wang Q, Niu Y, Jiang F, Wang J, Sheng L, Dai J. Xu H, et al. Bone Res. 2025 Feb 14;13(1):23. doi: 10.1038/s41413-025-00402-7. Bone Res. 2025. PMID: 39952914 Free PMC article.

115

Golgi-restored vesicular replenishment retards bone aging and empowers aging bone regeneration.

Liu P, Guo H, Huang X, Liu A, Zhu T, Zheng C, Fu F, Zhang K, Li S, Luo X, Tian J, Jin Y, Xuan K, Sui B. Liu P, et al. Bone Res. 2025 Feb 8;13(1):21. doi: 10.1038/s41413-024-00386-w. Bone Res. 2025. PMID: 39922812 Free PMC article.

116

Nuclear farnesoid X receptor protects against bone loss by driving osteoblast differentiation through stabilizing RUNX2.

Dong Q, Fu H, Li W, Ji X, Yin Y, Zhang Y, Zhu Y, Li G, Jia H, Zhang H, Wang H, Hu J, Wang G, Wu Z, Zhang Y, Xu S, Hou Z. Dong Q, et al. Bone Res. 2025 Jan 30;13(1):20. doi: 10.1038/s41413-024-00394-w. Bone Res. 2025. PMID: 39885145 Free PMC article.

117

Signaling pathway mechanisms of circadian clock gene Bmal1 regulating bone and cartilage metabolism: a review.

Ze Y, Wu Y, Tan Z, Li R, Li R, Gao W, Zhao Q. Ze Y, et al. Bone Res. 2025 Jan 27;13(1):19. doi: 10.1038/s41413-025-00403-6. Bone Res. 2025. PMID: 39870641 Free PMC article. Review.

118

Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with Wnt pathway dysregulation.

Alhashmi M, Gremida AME, Maharana SK, Antonaci M, Kerr A, Fu S, Lunn S, Turner DA, Al-Maslamani NA, Liu K, Meschis MM, Sutherland H, Wilson P, Clegg P, Wheeler GN, van 't Hof RJ, Bou-Gharios G, Yamamoto K. Alhashmi M, et al. Bone Res. 2025 Jan 26;13(1):17. doi: 10.1038/s41413-024-00393-x. Bone Res. 2025. PMID: 39865089 Free PMC article.

119

Enhancer-driven Shh signaling promotes glia-to-mesenchyme transition during bone repair.

Shen X, Zhang H, Song Z, Dong Y, Ge X, Jin S, Guo S, Zhang P, Fu Y, Zhu Y, Xiao N, Wang D, Cheng J, Xu R, Jiang H. Shen X, et al. Bone Res. 2025 Jan 26;13(1):16. doi: 10.1038/s41413-024-00396-8. Bone Res. 2025. PMID: 39865079 Free PMC article.

120

Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis.

Fan Y, Chen Z, Wang H, Jiang M, Lu H, Wei Y, Hu Y, Mo L, Liu Y, Zhou C, He W, Chen Z. Fan Y, et al. Bone Res. 2025 Jan 26;13(1):18. doi: 10.1038/s41413-024-00390-0. Bone Res. 2025. PMID: 39865068 Free PMC article.

121

Role of macrophage in intervertebral disc degeneration.

Dou Y, Zhang Y, Liu Y, Sun X, Liu X, Li B, Yang Q. Dou Y, et al. Bone Res. 2025 Jan 23;13(1):15. doi: 10.1038/s41413-024-00397-7. Bone Res. 2025. PMID: 39848963 Free PMC article. Review.

122

Skeletal abnormalities caused by a Connexin43_R239Q mutation in a mouse model for autosomal recessive craniometaphyseal dysplasia.

Fujii Y, Okabe I, Hatori A, Sah SK, Kanaujiya J, Fisher M, Norris R, Terasaki M, Reichenberger EJ, Chen IP. Fujii Y, et al. Bone Res. 2025 Jan 23;13(1):14. doi: 10.1038/s41413-024-00383-z. Bone Res. 2025. PMID: 39848944 Free PMC article.

123

GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147.

You Y, Huo K, He L, Wang T, Zhao L, Li R, Cheng X, Ma X, Yue Z, Siwko S, Wang N, Liao L, Liu M, Luo J. You Y, et al. Bone Res. 2025 Jan 21;13(1):13. doi: 10.1038/s41413-024-00389-7. Bone Res. 2025. PMID: 39837853 Free PMC article.

124

FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia.

Morice A, de La Seiglière A, Kany A, Khonsari RH, Bensidhoum M, Puig-Lombardi ME, Legeai Mallet L. Morice A, et al. Bone Res. 2025 Jan 21;13(1):12. doi: 10.1038/s41413-024-00385-x. Bone Res. 2025. PMID: 39837840 Free PMC article.

125

Polycystin-1 regulates tendon-derived mesenchymal stem cells fate and matrix organization in heterotopic ossification.

Xu YL, Huang M, Zhang Y, Su XY, Huang M, Zou NY, Jiao YR, Sun YC, Liu L, Lei YH, Li CJ. Xu YL, et al. Bone Res. 2025 Jan 20;13(1):11. doi: 10.1038/s41413-024-00392-y. Bone Res. 2025. PMID: 39833160 Free PMC article.

126

Fibrocyte enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity.

Sun Y, Peng Y, Su Z, So KKH, Lu Q, Lyu M, Zuo J, Huang Y, Guan Z, Cheung KMC, Zheng Z, Zhang X, Leung VYL. Sun Y, et al. Bone Res. 2025 Jan 20;13(1):10. doi: 10.1038/s41413-024-00372-2. Bone Res. 2025. PMID: 39828732 Free PMC article.

127

Melanoma bone metastasis-induced osteocyte ferroptosis via the HIF1α-HMOX1 axis.

Jia Y, Li R, Li Y, Kachler K, Meng X, Gießl A, Qin Y, Zhang F, Liu N, Andreev D, Schett G, Bozec A. Jia Y, et al. Bone Res. 2025 Jan 16;13(1):9. doi: 10.1038/s41413-024-00384-y. Bone Res. 2025. PMID: 39814705 Free PMC article.

128

Differential bone and vessel type formation at superior and dura periosteum during cranial bone defect repair.

Zhai Y, Zhou Z, Xing X, Nuzzle M, Zhang X. Zhai Y, et al. Bone Res. 2025 Jan 13;13(1):8. doi: 10.1038/s41413-024-00379-9. Bone Res. 2025. PMID: 39805832 Free PMC article.

129

Deep imaging of LepR⁺ stromal cells in optically cleared murine bone hemisections.

Ni Y, Wu J, Liu F, Yi Y, Meng X, Gao X, Xiao L, Zhou W, Chen Z, Chu P, Xing D, Yuan Y, Ding D, Shen G, Yang M, Wu R, Wang L, Melo LMN, Lin S, Cheng X, Li G, Tasdogan A, Ubellacker JM, Zhao H, Fang S, Shen B. Ni Y, et al. Bone Res. 2025 Jan 13;13(1):6. doi: 10.1038/s41413-024-00387-9. Bone Res. 2025. PMID: 39800733 Free PMC article.

130

MYSM1 attenuates osteoarthritis by recruiting PP2A to deubiquitinate and dephosphorylate RIPK2.

Wei K, Zhou C, Shu Z, Shang X, Zou Y, Zhou W, Xu H, Liang Y, Ma T, Sun X, Xiao J. Wei K, et al. Bone Res. 2025 Jan 2;13(1):3. doi: 10.1038/s41413-024-00368-y. Bone Res. 2025. PMID: 39746943 Free PMC article.

131

Discoidin domain receptor 2 is an important modulator of BMP signaling during heterotopic bone formation.

Wu F, Ge C, Pan H, Han Y, Mishina Y, Kaartinen V, Franceschi RT. Wu F, et al. Bone Res. 2025 Jan 2;13(1):7. doi: 10.1038/s41413-024-00391-z. Bone Res. 2025. PMID: 39746922 Free PMC article.

132

Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice, monkeys and humans.

Huang S, Gao D, Li Z, He H, Yu X, You X, Wu D, Du Z, Zeng J, Shi X, Hu Q, Nie Y, Zhang Z, Luo Z, Wang D, Zhao Z, Li L, Wang G, Wang L, Zhou Z, Chen D, Yang F. Huang S, et al. Bone Res. 2025 Jan 2;13(1):4. doi: 10.1038/s41413-024-00382-0. Bone Res. 2025. PMID: 39746903 Free PMC article.

133

Tree shrew as a new animal model for musculoskeletal disorders and aging.

Wei X, Li H, Qiu J, Jiao J, Guo X, Yin G, Yang P, Han Y, Zhao Q, Zeng H, Rao Z, Gao X, Li K, Lai P, Zhang S, Yang C, Lu D, Bai X. Wei X, et al. Bone Res. 2025 Jan 2;13(1):5. doi: 10.1038/s41413-024-00367-z. Bone Res. 2025. PMID: 39746902 Free PMC article.

134

Skeletal interoception and prospective application in biomaterials for bone regeneration.

Bai L, Li J, Li G, Zhou D, Su J, Liu C. Bai L, et al. Bone Res. 2025 Jan 2;13(1):1. doi: 10.1038/s41413-024-00378-w. Bone Res. 2025. PMID: 39743568 Free PMC article. Review.

135

Pivotal roles of biglycan and decorin in regulating bone mass, water retention, and bone toughness.

Hua R, Han Y, Ni Q, Fajardo RJ, Iozzo RV, Ahmed R, Nyman JS, Wang X, Jiang JX. Hua R, et al. Bone Res. 2025 Jan 2;13(1):2. doi: 10.1038/s41413-024-00380-2. Bone Res. 2025. PMID: 39743559 Free PMC article.

136

Cellular and molecular mechanisms underlying obesity in degenerative spine and joint diseases.

Xiang Q, Wu Z, Zhao Y, Tian S, Lin J, Wang L, Jiang S, Sun Z, Li W. Xiang Q, et al. Bone Res. 2024 Dec 11;12(1):71. doi: 10.1038/s41413-024-00388-8. Bone Res. 2024. PMID: 39658574 Free PMC article. Review.

137

Enhanced osteogenic potential of iPSC-derived mesenchymal progenitor cells following genome editing of GWAS variants in the RUNX1 gene.

Khan NM, Wilderman A, Kaiser JM, Kamalakar A, Goudy SL, Cotney J, Drissi H. Khan NM, et al. Bone Res. 2024 Dec 6;12(1):70. doi: 10.1038/s41413-024-00369-x. Bone Res. 2024. PMID: 39643619 Free PMC article.

138

Cross-talk of inflammation and cellular senescence: a new insight into the occurrence and progression of osteoarthritis.

Han Z, Wang K, Ding S, Zhang M. Han Z, et al. Bone Res. 2024 Dec 3;12(1):69. doi: 10.1038/s41413-024-00375-z. Bone Res. 2024. PMID: 39627227 Free PMC article. Review.

139

DNMT aberration-incurred GPX4 suppression prompts osteoblast ferroptosis and osteoporosis.

Ruan B, Dong J, Wei F, Huang Z, Yang B, Zhang L, Li C, Dong H, Cao W, Wang H, Wang Y. Ruan B, et al. Bone Res. 2024 Dec 2;12(1):68. doi: 10.1038/s41413-024-00365-1. Bone Res. 2024. PMID: 39617773 Free PMC article.

140

KMT2A regulates the autophagy-GATA4 axis through METTL3-mediated m⁶A modification of ATG4a to promote NPCs senescence and IVDD progression.

Wu O, Jin Y, Zhang Z, Zhou H, Xu W, Chen L, Jones M, Kwan KYH, Gao J, Zhang K, Cheng X, Chen Q, Wang X, Li YM, Guo Z, Sun J, Chen Z, Wang B, Wang X, Shen S, Wu A. Wu O, et al. Bone Res. 2024 Nov 21;12(1):67. doi: 10.1038/s41413-024-00373-1. Bone Res. 2024. PMID: 39572532 Free PMC article.

141

Engineering bone/cartilage organoids: strategy, progress, and application.

Bai L, Zhou D, Li G, Liu J, Chen X, Su J. Bai L, et al. Bone Res. 2024 Nov 20;12(1):66. doi: 10.1038/s41413-024-00376-y. Bone Res. 2024. PMID: 39567500 Free PMC article. Review.

142

Bone loss with aging is independent of gut microbiome in mice.

You X, Yan J, Herzog J, Nobakhti S, Campbell R, Hoke A, Hammamieh R, Sartor RB, Shefelbine S, Kacena MA, Chakraborty N, Charles JF. You X, et al. Bone Res. 2024 Nov 11;12(1):65. doi: 10.1038/s41413-024-00366-0. Bone Res. 2024. PMID: 39523344 Free PMC article.

143

Inhibition of sympathetic tone via hypothalamic descending pathway propagates glucocorticoid-induced endothelial impairment and osteonecrosis of the femoral head.

Shao W, Wang B, Wang P, Zhang S, Gong S, Guo X, Duan D, Shao Z, Liu W, He L, Gao F, Lv X, Feng Y. Shao W, et al. Bone Res. 2024 Nov 8;12(1):64. doi: 10.1038/s41413-024-00371-3. Bone Res. 2024. PMID: 39516484 Free PMC article.

144

IRF1-mediated upregulation of PARP12 promotes cartilage degradation by inhibiting PINK1/Parkin dependent mitophagy through ISG15 attenuating ubiquitylation and SUMOylation of MFN1/2.

Deng Z, Long D, Li C, Liu H, Li W, Zhong Y, Mo X, Li R, Yang Z, Kang Y, Mao G. Deng Z, et al. Bone Res. 2024 Oct 28;12(1):63. doi: 10.1038/s41413-024-00363-3. Bone Res. 2024. PMID: 39465252 Free PMC article.

145

Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect.

El-Masri BM, Andreasen CM, Laursen KS, Kofod VB, Dahl XG, Nielsen MH, Thomsen JS, Brüel A, Sørensen MS, Hansen LJ, Kim AS, Taylor VE, Massarotti C, McDonald MM, You X, Charles JF, Delaisse JM, Andersen TL. El-Masri BM, et al. Bone Res. 2024 Oct 18;12(1):62. doi: 10.1038/s41413-024-00362-4. Bone Res. 2024. PMID: 39424806 Free PMC article.

146

Osteopetrosis-like disorders induced by osteoblast-specific retinoic acid signaling inhibition in mice.

Sun S, Liu Y, Sun J, Zan B, Cui Y, Jin A, Xu H, Huang X, Zhu Y, Yang Y, Gao X, Lu T, Wang X, Liu J, Mei L, Shen L, Dai Q, Jiang L. Sun S, et al. Bone Res. 2024 Oct 17;12(1):61. doi: 10.1038/s41413-024-00353-5. Bone Res. 2024. PMID: 39419968 Free PMC article.

147

A monoallelic variant in CCN2 causes an autosomal dominant spondyloepimetaphyseal dysplasia with low bone mass.

Li S, Shao R, Li S, Zhao J, Deng Q, Li P, Wei Z, Xu S, Chen L, Li B, Zou W, Zhang Z. Li S, et al. Bone Res. 2024 Oct 16;12(1):60. doi: 10.1038/s41413-024-00364-2. Bone Res. 2024. PMID: 39414788 Free PMC article.

148

Versatility of 14-3-3 proteins and their roles in bone and joint-related diseases.

Zhou R, Hu W, Ma PX, Liu CJ. Zhou R, et al. Bone Res. 2024 Oct 15;12(1):58. doi: 10.1038/s41413-024-00370-4. Bone Res. 2024. PMID: 39406741 Free PMC article. Review.

149

Periostin⁺ myeloid cells improved long bone regeneration in a mechanosensitive manner.

Wang Z, Lin M, Pan Y, Liu Y, Yang C, Wu J, Wang Y, Yan B, Zhou J, Chen R, Liu C. Wang Z, et al. Bone Res. 2024 Oct 15;12(1):59. doi: 10.1038/s41413-024-00361-5. Bone Res. 2024. PMID: 39406726 Free PMC article.

150

Metabolic reprogramming in skeletal cell differentiation.

Bertels JC, He G, Long F. Bertels JC, et al. Bone Res. 2024 Oct 11;12(1):57. doi: 10.1038/s41413-024-00374-0. Bone Res. 2024. PMID: 39394187 Free PMC article. Review.

151

Multimodal analyses of immune cells during bone repair identify macrophages as a therapeutic target in musculoskeletal trauma.

Hachemi Y, Perrin S, Ethel M, Julien A, Vettese J, Geisler B, Göritz C, Colnot C. Hachemi Y, et al. Bone Res. 2024 Sep 29;12(1):56. doi: 10.1038/s41413-024-00347-3. Bone Res. 2024. PMID: 39341816 Free PMC article.

152

Spatial multiplexed immunofluorescence analysis reveals coordinated cellular networks associated with overall survival in metastatic osteosarcoma.

Lacinski RA, Dziadowicz SA, Melemai VK, Fitzpatrick B, Pisquiy JJ, Heim T, Lohse I, Schoedel KE, Llosa NJ, Weiss KR, Lindsey BA. Lacinski RA, et al. Bone Res. 2024 Sep 27;12(1):55. doi: 10.1038/s41413-024-00359-z. Bone Res. 2024. PMID: 39333065 Free PMC article.

153

Pharmacologic or genetic targeting of peripheral nerves prevents peri-articular traumatic heterotopic ossification.

Zhu M, Yea JH, Li Z, Qin Q, Xu M, Xing X, Negri S, Archer M, Mittal M, Levi B, James AW. Zhu M, et al. Bone Res. 2024 Sep 26;12(1):54. doi: 10.1038/s41413-024-00358-0. Bone Res. 2024. PMID: 39327413 Free PMC article.

154

Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome.

Wang Y, Zhang W, Yang Y, Qin J, Wang R, Wang S, Fu W, Niu Q, Wang Y, Li C, Li H, Zhou Y, Liu M. Wang Y, et al. Bone Res. 2024 Sep 6;12(1):53. doi: 10.1038/s41413-024-00355-3. Bone Res. 2024. PMID: 39242551 Free PMC article.

155

Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects.

Yao Z, Ayoub A, Srinivasan V, Wu J, Tang C, Duan R, Milosavljevic A, Xing L, Ebetino FH, Frontier AJ, Boyce BF. Yao Z, et al. Bone Res. 2024 Sep 5;12(1):52. doi: 10.1038/s41413-024-00352-6. Bone Res. 2024. PMID: 39231935 Free PMC article.

156

Bone targeted nano-drug and nano-delivery.

Wu Y, Sun B, Tang Y, Shen A, Lin Y, Zhao X, Li J, Monteiro MJ, Gu W. Wu Y, et al. Bone Res. 2024 Sep 4;12(1):51. doi: 10.1038/s41413-024-00356-2. Bone Res. 2024. PMID: 39231955 Free PMC article. Review.

157

Targeting Fascin1 maintains chondrocytes phenotype and attenuates osteoarthritis development.

Yang P, Xiao Y, Chen L, Yang C, Cheng Q, Li H, Chen D, Wu J, Liao Z, Yang C, Wang C, Wang H, Huang B, Ke E, Bai X, Li K. Yang P, et al. Bone Res. 2024 Sep 4;12(1):50. doi: 10.1038/s41413-024-00357-1. Bone Res. 2024. PMID: 39231936 Free PMC article.

158

Osteoclasts control endochondral ossification via regulating acetyl-CoA availability.

Deng D, Liu X, Huang W, Yuan S, Liu G, Ai S, Fu Y, Xu H, Zhang X, Li S, Xu S, Bai X, Zhang Y. Deng D, et al. Bone Res. 2024 Aug 28;12(1):49. doi: 10.1038/s41413-024-00360-6. Bone Res. 2024. PMID: 39198395 Free PMC article.

159

The HOXC10/NOD1/ERK axis drives osteolytic bone metastasis of pan-KRAS-mutant lung cancer.

Li K, Yang B, Du Y, Ding Y, Shen S, Sun Z, Liu Y, Wang Y, Cao S, Ren W, Wang X, Li M, Zhang Y, Wu J, Zheng W, Yan W, Li L. Li K, et al. Bone Res. 2024 Aug 27;12(1):47. doi: 10.1038/s41413-024-00350-8. Bone Res. 2024. PMID: 39191757 Free PMC article.

160

SREBP2 restricts osteoclast differentiation and activity by regulating IRF7 and limits inflammatory bone erosion.

Kim H, Choi IA, Umemoto A, Bae S, Kaneko K, Mizuno M, Giannopoulou E, Pannellini T, Deng L, Park-Min KH. Kim H, et al. Bone Res. 2024 Aug 27;12(1):48. doi: 10.1038/s41413-024-00354-4. Bone Res. 2024. PMID: 39191742 Free PMC article.

161

Schnurri-3 inhibition rescues skeletal fragility and vascular skeletal stem cell niche pathology in the OIM model of osteogenesis imperfecta.

Li N, Shi B, Li Z, Han J, Sun J, Huang H, Yallowitz AR, Bok S, Xiao S, Wu Z, Chen Y, Xu Y, Qin T, Huang R, Zheng H, Shen R, Meng L, Greenblatt MB, Xu R. Li N, et al. Bone Res. 2024 Aug 26;12(1):46. doi: 10.1038/s41413-024-00349-1. Bone Res. 2024. PMID: 39183236 Free PMC article.

162

Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy alleviates aged-related bone loss and extends lifespan in middle aged mice.

Luo Z, Wei W, Qiu D, Su Z, Liu L, Zhou H, Cui H, Yang L. Luo Z, et al. Bone Res. 2024 Aug 21;12(1):45. doi: 10.1038/s41413-024-00351-7. Bone Res. 2024. PMID: 39164234 Free PMC article.

163

Coactivator-independent vitamin D receptor signaling causes severe rickets in mice, that is not prevented by a diet high in calcium, phosphate, and lactose.

Doms S, Verlinden L, Janssens I, Vanhevel J, Eerlings R, Houtman R, Kato S, Mathieu C, Decallonne B, Carmeliet G, Verstuyf A. Doms S, et al. Bone Res. 2024 Aug 20;12(1):44. doi: 10.1038/s41413-024-00343-7. Bone Res. 2024. PMID: 39164247 Free PMC article.

164

Induction of osteoblast apoptosis stimulates macrophage efferocytosis and paradoxical bone formation.

Batoon L, Koh AJ, Millard SM, Grewal J, Choo FM, Kannan R, Kinnaird A, Avey M, Teslya T, Pettit AR, McCauley LK, Roca H. Batoon L, et al. Bone Res. 2024 Aug 5;12(1):43. doi: 10.1038/s41413-024-00341-9. Bone Res. 2024. PMID: 39103355 Free PMC article.

165

Mi B, Xiong Y, Knoedler S, Alfertshofer M, Panayi AC, Wang H, Lin S, Li G, Liu G. Mi B, et al. Bone Res. 2024 Aug 5;12(1):42. doi: 10.1038/s41413-024-00346-4. Bone Res. 2024. PMID: 39103328 Free PMC article. Review.

166

PDZK1 protects against mechanical overload-induced chondrocyte senescence and osteoarthritis by targeting mitochondrial function.

Shao Y, Zhang H, Guan H, Wu C, Qi W, Yang L, Yin J, Zhang H, Liu L, Lu Y, Zhao Y, Zhang S, Zeng C, Wang G, Bai X, Cai D. Shao Y, et al. Bone Res. 2024 Jul 17;12(1):41. doi: 10.1038/s41413-024-00344-6. Bone Res. 2024. PMID: 39019845 Free PMC article.

167

Caspase-8 promotes scramblase-mediated phosphatidylserine exposure and fusion of osteoclast precursors.

Krishnacoumar B, Stenzel M, Garibagaoglu H, Omata Y, Sworn RL, Hofmann T, Ipseiz N, Czubala MA, Steffen U, Maccataio A, Stoll C, Böhm C, Herrmann M, Uderhardt S, Jenkins RH, Taylor PR, Grüneboom A, Zaiss MM, Schett G, Krönke G, Scholtysek C. Krishnacoumar B, et al. Bone Res. 2024 Jul 11;12(1):40. doi: 10.1038/s41413-024-00338-4. Bone Res. 2024. PMID: 38987568 Free PMC article.

168

Wnt/β-catenin signaling components and mechanisms in bone formation, homeostasis, and disease.

Hu L, Chen W, Qian A, Li YP. Hu L, et al. Bone Res. 2024 Jul 10;12(1):39. doi: 10.1038/s41413-024-00342-8. Bone Res. 2024. PMID: 38987555 Free PMC article. Review.

169

PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging.

Xie L, Cheng Y, Hu B, Chen X, An Y, Xia Z, Cai G, Li C, Peng H. Xie L, et al. Bone Res. 2024 Jul 4;12(1):38. doi: 10.1038/s41413-024-00337-5. Bone Res. 2024. PMID: 38961077 Free PMC article.

170

FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development.

Pei F, Guo T, Zhang M, Ma L, Jing J, Feng J, Ho TV, Wen Q, Chai Y. Pei F, et al. Bone Res. 2024 Jun 24;12(1):37. doi: 10.1038/s41413-024-00345-5. Bone Res. 2024. PMID: 38910207 Free PMC article.

171

Retraction Note: Circular RNA circStag1 promotes bone regeneration by interacting with HuR.

Chen G, Long C, Wang S, Wang Z, Chen X, Tang W, He X, Bao Z, Tan B, Zhao J, Xie Y, Li Z, Yang D, Xiao G, Peng S. Chen G, et al. Bone Res. 2024 Jun 24;12(1):36. doi: 10.1038/s41413-024-00348-2. Bone Res. 2024. PMID: 38910170 Free PMC article. No abstract available.

172

Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor.

Kobayashi H, Terkawi MA, Ota M, Hasegawa T, Yamamoto T, Shimizu T, Sato D, Fujita R, Murakami T, Amizuka N, Iwasaki N, Takahata M. Kobayashi H, et al. Bone Res. 2024 Jun 7;12(1):35. doi: 10.1038/s41413-024-00340-w. Bone Res. 2024. PMID: 38849345 Free PMC article.

173

Lumbar instability remodels cartilage endplate to induce intervertebral disc degeneration by recruiting osteoclasts via Hippo-CCL3 signaling.

Li H, Tang Y, Liu Z, Chen K, Zhang K, Hu S, Pan C, Yang H, Li B, Chen H. Li H, et al. Bone Res. 2024 May 30;12(1):34. doi: 10.1038/s41413-024-00331-x. Bone Res. 2024. PMID: 38816384 Free PMC article.

174

ATP6AP2, a regulator of LRP6/β-catenin protein trafficking, promotes Wnt/β-catenin signaling and bone formation in a cell type dependent manner.

Xiong L, Guo HH, Pan JX, Ren X, Lee D, Chen L, Mei L, Xiong WC. Xiong L, et al. Bone Res. 2024 May 29;12(1):33. doi: 10.1038/s41413-024-00335-7. Bone Res. 2024. PMID: 38811544 Free PMC article.

175

Matrix stiffening promotes chondrocyte senescence and the osteoarthritis development through downregulating HDAC3.

Fu B, Shen J, Zou X, Sun N, Zhang Z, Liu Z, Zeng C, Liu H, Huang W. Fu B, et al. Bone Res. 2024 May 24;12(1):32. doi: 10.1038/s41413-024-00333-9. Bone Res. 2024. PMID: 38789434 Free PMC article.

176

Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis.

Chen H, Fu X, Wu X, Zhao J, Qiu F, Wang Z, Wang Z, Chen X, Xie D, Huang J, Fan J, Yang X, Song Y, Li J, He D, Xiao G, Lu A, Liang C. Chen H, et al. Bone Res. 2024 May 23;12(1):31. doi: 10.1038/s41413-024-00336-6. Bone Res. 2024. PMID: 38782893 Free PMC article.

177

Author Correction: FAR591 promotes the pathogenesis and progression of SONFH by regulating Fos expression to mediate the apoptosis of bone microvascular endothelial cells.

Zhang F, Wei L, Wang L, Wang T, Xie Z, Luo H, Li F, Zhang J, Dong W, Liu G, Kang Q, Zhu X, Peng W. Zhang F, et al. Bone Res. 2024 May 20;12(1):30. doi: 10.1038/s41413-024-00339-3. Bone Res. 2024. PMID: 38769361 Free PMC article. No abstract available.

178

RUFY4 deletion prevents pathological bone loss by blocking endo-lysosomal trafficking of osteoclasts.

Kim M, Park JH, Go M, Lee N, Seo J, Lee H, Kim D, Ha H, Kim T, Jeong MS, Kim S, Kim T, Kim HS, Kang D, Shim H, Lee SY. Kim M, et al. Bone Res. 2024 May 15;12(1):29. doi: 10.1038/s41413-024-00326-8. Bone Res. 2024. PMID: 38744829 Free PMC article.

179

Prospects and challenges for the application of tissue engineering technologies in the treatment of bone infections.

Qin L, Yang S, Zhao C, Yang J, Li F, Xu Z, Yang Y, Zhou H, Li K, Xiong C, Huang W, Hu N, Hu X. Qin L, et al. Bone Res. 2024 May 14;12(1):28. doi: 10.1038/s41413-024-00332-w. Bone Res. 2024. PMID: 38744863 Free PMC article. Review.

180

Multi-omics analysis of human tendon adhesion reveals that ACKR1-regulated macrophage migration is involved in regeneration.

Zhang X, Xiao Y, Hu B, Li Y, Zhang S, Tian J, Wang S, Tao Z, Zeng X, Liu NN, Li B, Liu S. Zhang X, et al. Bone Res. 2024 May 7;12(1):27. doi: 10.1038/s41413-024-00324-w. Bone Res. 2024. PMID: 38714649 Free PMC article.

181

Pannexins in the musculoskeletal system: new targets for development and disease progression.

Luo Y, Zheng S, Xiao W, Zhang H, Li Y. Luo Y, et al. Bone Res. 2024 May 6;12(1):26. doi: 10.1038/s41413-024-00334-8. Bone Res. 2024. PMID: 38705887 Free PMC article. Review.

182

Author Correction: Insights and implications of sexual dimorphism in osteoporosis.

Zhang YY, Xie N, Sun XD, Nice EC, Liou YC, Huang C, Zhu H, Shen Z. Zhang YY, et al. Bone Res. 2024 Apr 15;12(1):25. doi: 10.1038/s41413-024-00329-5. Bone Res. 2024. PMID: 38622123 Free PMC article. No abstract available.

183

Sorafenib inhibits ossification of the posterior longitudinal ligament by blocking LOXL2-mediated vascularization.

Wang L, Jiang W, Zhao S, Xie D, Chen Q, Zhao Q, Wu H, Luo J, Yang L. Wang L, et al. Bone Res. 2024 Apr 10;12(1):24. doi: 10.1038/s41413-024-00327-7. Bone Res. 2024. PMID: 38594260 Free PMC article.

184

Cell membrane vesicles derived from hBMSCs and hUVECs enhance bone regeneration.

Wang D, Guo Y, Heng BC, Zhang X, Wei Y, He Y, Xu M, Xia B, Deng X. Wang D, et al. Bone Res. 2024 Apr 9;12(1):23. doi: 10.1038/s41413-024-00325-9. Bone Res. 2024. PMID: 38594236 Free PMC article.

185

The pathogenic mechanism of syndactyly type V identified in a Hoxd13Q50R knock-in mice.

Wang H, Chen X, Meng X, Cao Y, Han S, Liu K, Zhao X, Zhao X, Zhang X. Wang H, et al. Bone Res. 2024 Apr 1;12(1):21. doi: 10.1038/s41413-024-00322-y. Bone Res. 2024. PMID: 38561387 Free PMC article.

186

Skeletal interoception in osteoarthritis.

Yang D, Xu J, Xu K, Xu P. Yang D, et al. Bone Res. 2024 Apr 1;12(1):22. doi: 10.1038/s41413-024-00328-6. Bone Res. 2024. PMID: 38561376 Free PMC article. Review.

187

Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx.

Xiang Z, Zhang P, Jia C, Xu R, Cao D, Xu Z, Lu T, Liu J, Wang X, Qiu C, Fu W, Li W, Cheng L, Yang Q, Feng S, Wang L, Zhao Y, Liu X. Xiang Z, et al. Bone Res. 2024 Mar 29;12(1):20. doi: 10.1038/s41413-024-00317-9. Bone Res. 2024. PMID: 38553442 Free PMC article.

188

Kdm6a-CNN1 axis orchestrates epigenetic control of trauma-induced spinal cord microvascular endothelial cell senescence to balance neuroinflammation for improved neurological repair.

Li C, Qin T, Zhao J, Jin Y, Qin Y, He R, Wu T, Duan C, Jiang L, Yuan F, Lu H, Cao Y, Hu J. Li C, et al. Bone Res. 2024 Mar 25;12(1):19. doi: 10.1038/s41413-024-00323-x. Bone Res. 2024. PMID: 38528029 Free PMC article.

189

β-Receptor blocker enhances the anabolic effect of PTH after osteoporotic fracture.

Huang J, Wu T, Jiang YR, Zheng XQ, Wang H, Liu H, Wang H, Leng HJ, Fan DW, Yuan WQ, Song CL. Huang J, et al. Bone Res. 2024 Mar 21;12(1):18. doi: 10.1038/s41413-024-00321-z. Bone Res. 2024. PMID: 38514644 Free PMC article.

190

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair.

Kang H, Strong AL, Sun Y, Guo L, Juan C, Bancroft AC, Choi JH, Pagani CA, Fernandes AA, Woodard M, Lee J, Ramesh S, James AW, Hudson D, Dalby KN, Xu L, Tower RJ, Levi B. Kang H, et al. Bone Res. 2024 Mar 12;12(1):17. doi: 10.1038/s41413-024-00320-0. Bone Res. 2024. PMID: 38472175 Free PMC article.

191

Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and pain.

Gao F, Hu Q, Chen W, Li J, Qi C, Yan Y, Qian C, Wan M, Ficke J, Zheng J, Cao X. Gao F, et al. Bone Res. 2024 Mar 5;12(1):16. doi: 10.1038/s41413-024-00316-w. Bone Res. 2024. PMID: 38443372 Free PMC article.

192

Targeted knockdown of PGAM5 in synovial macrophages efficiently alleviates osteoarthritis.

Liu Y, Hao R, Lv J, Yuan J, Wang X, Xu C, Ma D, Duan Z, Zhang B, Dai L, Cheng Y, Lu W, Zhang X. Liu Y, et al. Bone Res. 2024 Mar 4;12(1):15. doi: 10.1038/s41413-024-00318-8. Bone Res. 2024. PMID: 38433252 Free PMC article.

193

A DNA tetrahedron-based ferroptosis-suppressing nanoparticle: superior delivery of curcumin and alleviation of diabetic osteoporosis.

Li Y, Cai Z, Ma W, Bai L, Luo E, Lin Y. Li Y, et al. Bone Res. 2024 Feb 29;12(1):14. doi: 10.1038/s41413-024-00319-7. Bone Res. 2024. PMID: 38424439 Free PMC article.

194

Aging impairs the osteocytic regulation of collagen integrity and bone quality.

Schurman CA, Kaya S, Dole N, Luna NMM, Castillo N, Potter R, Rose JP, Bons J, King CD, Burton JB, Schilling B, Melov S, Tang S, Schaible E, Alliston T. Schurman CA, et al. Bone Res. 2024 Feb 26;12(1):13. doi: 10.1038/s41413-023-00303-7. Bone Res. 2024. PMID: 38409111 Free PMC article.

195

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.

Brylka LJ, Alimy AR, Tschaffon-Müller MEA, Jiang S, Ballhause TM, Baranowsky A, von Kroge S, Delsmann J, Pawlus E, Eghbalian K, Püschel K, Schoppa A, Haffner-Luntzer M, Beech DJ, Beil FT, Amling M, Keller J, Ignatius A, Yorgan TA, Rolvien T, Schinke T. Brylka LJ, et al. Bone Res. 2024 Feb 23;12(1):12. doi: 10.1038/s41413-024-00315-x. Bone Res. 2024. PMID: 38395992 Free PMC article.

196

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