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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 2
1967 1
1968 2
1969 1
1970 2
1971 1
1973 3
1974 2
1975 4
1976 4
1977 4
1978 2
1979 9
1980 7
1981 8
1982 3
1983 8
1984 5
1985 8
1986 6
1987 9
1988 12
1989 13
1990 12
1991 16
1992 21
1993 41
1994 36
1995 30
1996 31
1997 49
1998 36
1999 44
2000 57
2001 44
2002 57
2003 54
2004 71
2005 90
2006 67
2007 75
2008 78
2009 91
2010 122
2011 110
2012 127
2013 113
2014 101
2015 110
2016 80
2017 88
2018 89
2019 34
2020 2
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1,878 results
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Page 1
Reduced energy availability: implications for bone health in physically active populations.
Papageorgiou M, et al. Eur J Nutr 2018 - Review. PMID 28721562 Free PMC article.
RESULTS: Available evidence indicates that short-term low EA may increase markers of bone resorption and decrease markers of bone formation in physically active women. Bone metabolic marker responses to low EA are less well known in physically active men. Cross-sectional studies investigating the effects of long-term low EA suggest that physically active individuals who have low EA present with lower bone mass, altered bone metabolism (favouring bone resorption), reduced bone strength and increased risk for stress fracture injuries. ...
RESULTS: Available evidence indicates that short-term low EA may increase markers of bone resorption and decrease markers of …
Regenerative potential of leucocyte- and platelet-rich fibrin. Part B: sinus floor elevation, alveolar ridge preservation and implant therapy. A systematic review
Castro AB, et al. J Clin Periodontol 2017 - Review. PMID 27891638 Free PMC article.
AIM: To analyse the effect of leucocyte- and platelet-rich fibrin (L-PRF) on bone regeneration procedures and osseointegration. ...L-PRF alone improved the preservation of the alveolar width, resulting in less buccal bone resorption compared to natural healing. ...
AIM: To analyse the effect of leucocyte- and platelet-rich fibrin (L-PRF) on bone regeneration procedures and osseointegration. ...L- …
6,7,4'-Trihydroxyflavone inhibits osteoclast formation and bone resorption in vitro and in vivo.
Kim EN, et al. Phytother Res 2019. PMID 31478281
In summary, THF inhibits RANKL-induced osteoclast differentiation by MAPK signaling pathway and inhibits bone resorption by destroying the actin ring in mature osteoclasts. THF also prevented LPS-induced bone loss in a mice model. Thus, THF may be useful in the treatment of bone diseases associated with excessive osteoclast differentiation and bone resorption....
In summary, THF inhibits RANKL-induced osteoclast differentiation by MAPK signaling pathway and inhibits bone resorption by de …
Mushroom Extracts Decrease Bone Resorption and Improve Bone Formation.
Erjavec I, et al. Int J Med Mushrooms 2016. PMID 27649725
Bone loss was monitored using densitometry (dual-energy X-ray absorptiometry) and micro computed tomography. In the concentration test, mushroom extracts showed no toxic effect on MC3T3-E1 cells; a dose of 24 µg/mL showed the most proliferative effect. ...In animals, mushroom extracts did not prevent trabecular bone loss in the long bones. However, we show for the first time that the treatment with a combination of extracts from L. edodes and G. frondosa significantly reduced trabecular bone loss at the lumbar spine. ...
Bone loss was monitored using densitometry (dual-energy X-ray absorptiometry) and micro computed tomography. In the concentration tes
Statins and alveolar bone resorption: a narrative review of preclinical and clinical studies.
de Monès E, et al. Oral Surg Oral Med Oral Pathol Oral Radiol 2015 - Review. PMID 25482549
CONTEXT: Tooth extraction and periodontal disease are both common clinical situations associated with alveolar bone loss. OBJECTIVE: To analyze the reported results of in vivo studies investigating the effectiveness of statins to reduce alveolar bone resorption. ...This review showed that the use of statins reduced significantly alveolar bone resorption observed during periodontal disease and after tooth extraction. ...
CONTEXT: Tooth extraction and periodontal disease are both common clinical situations associated with alveolar bone loss. OBJECTIVE: …
Calreticulin inhibits inflammation-induced osteoclastogenesis and bone resorption.
Fischer CR, et al. J Orthop Res 2017. PMID 28460421 Free article.
Osteoclasts play key roles in bone remodeling and pathologic osteolytic disorders such as inflammation, infection, bone implant loosening, rheumatoid arthritis, metastatic bone cancers, and pathological fractures. ...Recombinant human Calreticulin (rhCRT) inhibited lipopolysaccharide (LPS)-induced inflammatory osteoclastogenesis in the mouse calvarial bone in vivo. ...
Osteoclasts play key roles in bone remodeling and pathologic osteolytic disorders such as inflammation, infection, bone implan …
Sophocarpine attenuates wear particle-induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF-κB signalling pathway in a rat model.
Zhou CH, et al. Br J Pharmacol 2018. PMID 29130485 Free PMC article.
Therapeutic modalities based on inhibiting osteoclast formation and bone resorption have been confirmed to be an effective way of preventing aseptic prosthesis loosening. ...Our in vivo study showed that SPC prevented particle-induced prosthesis loosening by inhibiting osteoclast formation, resulting in reduced periprosthetic bone loss, diminished pseudomembrane formation, improved bone-implant contact, reduced bone resorption-related turnover and enhanced stability of implants. ...
Therapeutic modalities based on inhibiting osteoclast formation and bone resorption have been confirmed to be an effective way …
Porous architected biomaterial for a tibial-knee implant with minimum bone resorption and bone-implant interface micromotion.
Rahimizadeh A, et al. J Mech Behav Biomed Mater 2018. PMID 29247979
The outcome of applying this scheme is a graded lattice microarchitecture that can potentially offer the implant an improved degree of load bearing capacity while reducing concurrently bone resorption and interface micromotion. ...The numerical results suggest that the overall amount of bone resorption around the graded porous tibial stem is 26% lower than that around a conventional, commercially available, fully dense titanium implant of identical shape and size. ...
The outcome of applying this scheme is a graded lattice microarchitecture that can potentially offer the implant an improved degree of load …
Histologic and Radiographic Characteristics of Bone Filler Under Bisphosphonates.
Yifat M, et al. J Craniofac Surg 2019. PMID 30908448
BACKGROUND: Dental implants and bone augmentation are well-established procedures used for oral rehabilitation. There is an increasing interest in biological mediators used topically for prevention of bone resorption maybe enhancement of osseointegration of dental implants. ...Bone substitute was added to mandibular defects and was covered by a resorbable collagen membrane. In the study group, the membrane was soaked with bisphosphonates suspension. ...
BACKGROUND: Dental implants and bone augmentation are well-established procedures used for oral rehabilitation. There is an increasin …
The bone resorption inhibitors odanacatib and alendronate affect post-osteoclastic events differently in ovariectomized rabbits.
Jensen PR, et al. Calcif Tissue Int 2014. PMID 24085265 Free PMC article.
Odanacatib (ODN) is a bone resorption inhibitor which differs from standard antiresorptives by its ability to reduce bone resorption without decreasing bone formation. ...This increase is expected to favor the osteoclast-osteoblast interactions required for bone formation. Regarding bone resorption itself, we show that ODN, but not ALN, treatment results in shallower resorption lacunae, a geometry favoring bone stiffness. ...
Odanacatib (ODN) is a bone resorption inhibitor which differs from standard antiresorptives by its ability to reduce bone
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