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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 5
1946 14
1947 11
1948 10
1949 3
1951 13
1952 30
1953 8
1954 24
1955 38
1956 31
1957 56
1958 40
1959 39
1960 45
1961 47
1962 34
1964 15
1965 127
1966 258
1967 357
1968 341
1969 264
1970 290
1971 289
1972 287
1973 312
1974 271
1975 234
1976 228
1977 258
1978 264
1979 294
1980 289
1981 323
1982 342
1983 410
1984 380
1985 482
1986 618
1987 720
1988 784
1989 851
1990 923
1991 864
1992 1037
1993 1134
1994 1222
1995 1200
1996 1333
1997 1499
1998 1507
1999 1728
2000 1945
2001 1880
2002 1911
2003 2033
2004 2337
2005 2581
2006 2970
2007 3094
2008 3518
2009 3904
2010 4202
2011 4598
2012 4915
2013 5491
2014 5787
2015 6089
2016 3984
2017 3403
2018 3282
2019 1305
2020 14
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81,768 results
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Page 1
Focused ultrasound-mediated drug delivery through the blood-brain barrier.
Burgess A, et al. Expert Rev Neurother 2015 - Review. PMID 25936845 Free PMC article.
Despite recent advances in blood-brain barrier (BBB) research, it remains a significant hurdle for the pharmaceutical treatment of brain diseases. Focused ultrasound (FUS) is one method to transiently increase permeability of the BBB to promote drug delivery to specific brain regions. ...
Despite recent advances in blood-brain barrier (BBB) research, it remains a significant hurdle for the pharmaceutical treatment of …
Differential diagnosis for bilateral abnormalities of the basal ganglia and thalamus
Hegde AN, et al. Radiographics 2011 - Review. PMID 21257930
The basal ganglia are highly metabolically active and are symmetrically affected in toxic poisoning, metabolic abnormalities, and neurodegeneration with brain iron accumulation. ...The neuroimaging diagnosis is influenced not only by detection of specific MR imaging features such as restricted diffusion and the presence of hemorrhage, but also by detection of abnormalities involving other parts of the brain, especially the cerebral cortex, brainstem, and white matter. ...
The basal ganglia are highly metabolically active and are symmetrically affected in toxic poisoning, metabolic abnormalities, and neurodegen …
[Brain imaging and pathology in children with neurological diseases].
Takashima S. No To Hattatsu 2010 - Review. PMID 20666129 Japanese.
Morphological and functional imaging of the brain is rapidly developing, while knowledge of brain pathology is also progressing at the levels of protein and RNA along with molecular biology. In this review, brain imaging and pathology were compared developmentally. Brain imaging reveals the early stages and progression of brain damage, and the pathology confirms the characteristics of the lesions. ...
Morphological and functional imaging of the brain is rapidly developing, while knowledge of brain pathology is also pro …
Neural Profile of Callous Traits in Children: A Population-Based Neuroimaging Study
Bolhuis K, et al. Biol Psychiatry 2019. PMID 30554676 Free article.
Structural magnetic resonance imaging was used to investigate brain morphology using volumetric indices and whole-brain analyses (n = 2146); diffusion tensor imaging was used to assess global and specific white matter microstructure (n = 2059). RESULTS: Callous traits were associated with lower global brain (e.g., total brain) volumes as well as decreased cortical surface area in frontal and temporal regions. ...
Structural magnetic resonance imaging was used to investigate brain morphology using volumetric indices and whole-brain analys …
Cortical and Subcortical Gray Matter Volume in Youths With Conduct Problems: A Meta-analysis
Rogers JC and De Brito SA. JAMA Psychiatry 2016 - Review. PMID 26650724
OBJECTIVE: To conduct a meta-analysis of published whole-brain structural neuroimaging studies on youths with CP that used VBM methods to facilitate replication and aid further analyses by researchers. ...Studies were excluded if they (1) failed to use VBM, (2) failed to report a voxelwise comparison between youths with CP and typically developing (TD) youths, (3) used different significance or extent thresholds throughout the brain, (4) included duplicated datasets, and (5) did not provide peak coordinates or parametric maps after contact with the authors. ...
OBJECTIVE: To conduct a meta-analysis of published whole-brain structural neuroimaging studies on youths with CP that used VBM method …
Psychoradiological investigations of gray matter alterations in patients with anorexia nervosa
Zhang S, et al. Transl Psychiatry 2018. PMID 30546047 Free PMC article.
The underlying neurobiological mechanisms are not well understood, and high-resolution structural magnetic resonance brain imaging studies have given inconsistent results. ...These psychoradiological findings of the brain abnormalities might underpin the neuropathophysiology in AN....
The underlying neurobiological mechanisms are not well understood, and high-resolution structural magnetic resonance brain imaging st …
White matter alterations in anorexia nervosa: Evidence from a voxel-based meta-analysis
Barona M, et al. Neurosci Biobehav Rev 2019 - Review. PMID 30851283
Recent studies have sought to investigate differences in white matter microstructure in AN, with significant results in several brain regions. ...
Recent studies have sought to investigate differences in white matter microstructure in AN, with significant results in several brain
Afferent projections of the subthalamic nucleus in the rat: emphasis on bilateral and interhemispheric connections
Cavdar S, et al. Acta Neurobiol Exp (Wars) 2018. PMID 30295682 Free article.
Deep brain stimulation (DBS) is a standard surgical treatment for PD. Although DBS results in a significant reduction in motor disability, several negative side effects have been reported. ...
Deep brain stimulation (DBS) is a standard surgical treatment for PD. Although DBS results in a significant reduction in motor disabi …
Gray matter differences in patients with functional movement disorders
Maurer CW, et al. Neurology 2018 - Clinical Trial. PMID 30305450 Free PMC article.
We compared between-group differences in gray matter volume using voxel-based morphometry across the whole brain. All participants in addition underwent a thorough neuropsychological battery, including the Hamilton Anxiety and Depression Scales and the Childhood Trauma Questionnaire. ...RESULTS: Patients with functional movement disorders exhibited increased volume of the left amygdala, left striatum, left cerebellum, left fusiform gyrus, and bilateral thalamus, and decreased volume of the left sensorimotor cortex (whole-brain corrected p ≤ 0.05). ...
We compared between-group differences in gray matter volume using voxel-based morphometry across the whole brain. All participants in …
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