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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 5
1967 11
1968 7
1969 5
1970 8
1971 6
1972 14
1973 14
1974 19
1975 9
1976 12
1977 11
1978 15
1979 14
1980 5
1981 12
1982 4
1983 5
1984 13
1985 14
1986 11
1987 11
1988 10
1989 12
1990 17
1991 18
1992 16
1993 14
1994 14
1995 12
1996 16
1997 19
1998 23
1999 27
2000 30
2001 23
2002 32
2003 35
2004 46
2005 39
2006 50
2007 54
2008 42
2009 78
2010 90
2011 73
2012 84
2013 115
2014 123
2015 125
2016 146
2017 126
2018 135
2019 62
2020 0
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1,757 results
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Page 1
Prognostic utility of circulating nucleic acids in acute brain injuries.
Regner A, et al. Expert Rev Mol Diagn 2018 - Review. PMID 30307786
Acute brain injuries represent major causes of morbidity and mortality worldwide. Nevertheless, therapeutic options are centered mainly on supportive care, and accurate prognosis prediction following traumatic brain injury (TBI) or stroke remains a challenge in clinical settings. Areas covered: Circulating DNA and RNA have shown potential as predictive molecules in acute brain injuries. In particular, plasma cell-free DNA (cfDNA) levels have been correlated to severity, mortality, and outcome after TBI and stroke. ...
Acute brain injuries represent major causes of morbidity and mortality worldwide. Nevertheless, therapeutic options are center …
When the brain tells the blood how to clot.
Boilard E. Blood 2015. PMID 25814487
In this issue of Blood, Tian et al report that during traumatic brain injury, small membrane vesicles, called microparticles, disseminate procoagulant factors from the brain into the systemic circulation. The delivery appears to occur through the disrupted blood-brain barrier....
In this issue of Blood, Tian et al report that during traumatic brain injury, small membrane vesicles, called microparticles, …
Blood biomarkers for evaluation of perinatal encephalopathy: state of the art
Graham EM, et al. Curr Opin Pediatr 2018 - Review. PMID 29346139 Free PMC article.
Infants with neonatal brain injuries will likely be the first group whose management is dramatically altered with point-of-care, rapidly available brain biomarker analysis. ...RECENT FINDINGS: Highlighted findings from the past 18 months of publications on biomarkers in neonatal brain injury include; Specific nonbrain markers of cardiac health and global asphyxia continue to provide information on brain injury after hypoxic-ischemic encephalopathy (HIE). ...
Infants with neonatal brain injuries will likely be the first group whose management is dramatically altered with point-of-car …
Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood.
Zetterberg H, et al. Nat Rev Neurol 2013 - Review. PMID 23399646 Free PMC article.
Mild traumatic brain injury (TBI), which is defined as a head trauma resulting in a brief loss of consciousness and/or alteration of mental state, is usually benign, but occasionally causes persistent and sometimes progressive symptoms. Whether a threshold for the amount of brain injury and/or individual vulnerability might contribute to the development of these long-term consequences is unknown. ...
Mild traumatic brain injury (TBI), which is defined as a head trauma resulting in a brief loss of consciousness and/or alterat …
Advances in the understanding of trauma-induced coagulopathy
Chang R, et al. Blood 2016 - Review. PMID 27381903 Free PMC article.
The most common causes of death after trauma are hemorrhage and traumatic brain injury (TBI). The management of TIC has significant implications in both because many hemorrhagic deaths could be preventable, and TIC is associated with progression of intracranial injury after TBI. ...
The most common causes of death after trauma are hemorrhage and traumatic brain injury (TBI). The management of TIC has signif …
Blood and cerebrospinal fluid biomarkers
Kawata K, et al. Handb Clin Neurol 2018 - Review. PMID 30482350
Sports-related traumatic brain injuries (TBIs) range in severity from severe to subconcussive. Although technologies exist for clinical diagnosis of more severe injuries, methods for diagnosis of milder forms of brain injury are limited. ...Brain-specific biomarkers include proteins derived from neurons and glia, and are often measured to assess neural injury and repair, and to predict outcomes. ...
Sports-related traumatic brain injuries (TBIs) range in severity from severe to subconcussive. Although technologies exist for …
Sphingolipids and microRNA Changes in Blood following Blast Traumatic Brain Injury: An Exploratory Study.
Sajja VSSS, et al. J Neurotrauma 2018. PMID 29020847
At present, accurate and reliable biomarkers to ascertain the presence, severity, or prognosis of blast traumatic brain injury (bTBI) are lacking. ...Therefore, plasma analysis is an attractive approach with which to diagnose and treat brain injuries. Subacute changes in plasma microRNA (miRNA) and lipid composition for sphingolipids were evaluated in a murine model of mild-to-moderate bTBI using next-generation sequencing and mass spectroscopy respectively. ...
At present, accurate and reliable biomarkers to ascertain the presence, severity, or prognosis of blast traumatic brain injury
Biomarkers and acute brain injuries: interest and limits.
Mrozek S, et al. Crit Care 2014 - Review. PMID 25029344 Free PMC article.
For patients presenting with acute brain injury (such as traumatic brain injury, subarachnoid haemorrhage and stroke), the diagnosis and identification of intracerebral lesions and evaluation of the severity, prognosis and treatment efficacy can be challenging. The complexity and heterogeneity of lesions after brain injury are most probably responsible for this difficulty. Patients with apparently comparable brain lesions on imaging may have different neurological outcomes or responses to therapy. ...
For patients presenting with acute brain injury (such as traumatic brain injury, subarachnoid haemorrhage and st …
A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury.
Thelin EP, et al. Acta Neurochir (Wien) 2017 - Review. PMID 27957604 Free PMC article.
BACKGROUND: In order to improve injury assessment of brain injuries, protein markers of pathophysiological processes and tissue fate have been introduced in the clinic. ...RESULTS: S100B has successfully been implemented in the clinic regionally (1) to screen mild TBI patients evaluating the need to perform a head computerized tomography, (2) to predict outcome in moderate-to-severe TBI patients, (3) to detect secondary injury development in brain-injured patients and (4) to evaluate treatment efficacy. ...
BACKGROUND: In order to improve injury assessment of brain injuries, protein markers of pathophysiological processes an …
Behavioral, blood, and magnetic resonance imaging biomarkers of experimental mild traumatic brain injury.
Wright DK, et al. Sci Rep 2016. PMID 27349514 Free PMC article.
Repeated mild traumatic brain injuries (mTBI) may lead to serious neurological consequences, especially if re-injury occurs within the period of increased cerebral vulnerability (ICV) triggered by the initial insult. ...Rats were given a sham or mild fluid percussion injury (mFPI), and behavioral testing, MRI, and blood collections were conducted up to 30 days post-injury. ...
Repeated mild traumatic brain injuries (mTBI) may lead to serious neurological consequences, especially if re-injury oc …
1,757 results
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