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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1957 2
1958 2
1959 3
1960 2
1962 2
1964 1
1966 4
1967 11
1968 17
1969 24
1970 15
1971 25
1972 25
1973 29
1974 39
1975 38
1976 33
1977 29
1978 37
1979 41
1980 40
1981 49
1982 32
1983 41
1984 57
1985 78
1986 86
1987 116
1988 139
1989 185
1990 266
1991 273
1992 395
1993 438
1994 511
1995 596
1996 681
1997 743
1998 829
1999 920
2000 1096
2001 1122
2002 1237
2003 1308
2004 1450
2005 1593
2006 1818
2007 1947
2008 2187
2009 2321
2010 2865
2011 2789
2012 3026
2013 3112
2014 3389
2015 3694
2016 3588
2017 3367
2018 3221
2019 1581
2020 40
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Search Results

48,423 results
Results by year
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Page 1
Genomic characterization of metastatic breast cancers.
Bertucci F, et al. Nature 2019. PMID 31118521
Metastasis is the main cause of death for patients with breast cancer. Many studies have characterized the genomic landscape of breast cancer during its early stages. ...Finally, metastatic breast cancers showed an increase in mutational burden and clonal diversity compared to early breast cancers. ...
Metastasis is the main cause of death for patients with breast cancer. Many studies have characterized the genomic landscape of br
Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing.
Casasent AK, et al. Cell 2018. PMID 29307488 Free PMC article.
Ductal carcinoma in situ (DCIS) is an early-stage breast cancer that infrequently progresses to invasive ductal carcinoma (IDC). ...
Ductal carcinoma in situ (DCIS) is an early-stage breast cancer that infrequently progresses to invasive ductal carcinoma (IDC). ...
Clonal evolution in breast cancer revealed by single nucleus genome sequencing.
Wang Y, et al. Nature 2014. PMID 25079324 Free PMC article.
Sequencing studies of breast tumour cohorts have identified many prevalent mutations, but provide limited insight into the genomic diversity within tumours. ...These findings have important implications for the diagnosis, therapeutic treatment and evolution of chemoresistance in breast cancer....
Sequencing studies of breast tumour cohorts have identified many prevalent mutations, but provide limited insight into the genomic di …
Indications for Contralateral Prophylactic Mastectomy: A Consensus Statement Using Modified Delphi Methodology
Wright FC, et al. Ann Surg 2018. PMID 28594745
RESULTS: Our panelists did not recommend for average risk women with unilateral breast cancer. The panel recommended CPM for women with a unilateral breast cancer and previous Mantle field radiation or a BrCa1/2 gene mutation. ...CONCLUSION: Contralateral prophylactic mastectomy is rarely recommended for women with unilateral breast cancer....
RESULTS: Our panelists did not recommend for average risk women with unilateral breast cancer. The panel recommended CPM for women wi …
Punctuated copy number evolution and clonal stasis in triple-negative breast cancer.
Gao R, et al. Nat Genet 2016. PMID 27526321 Free PMC article.
Aneuploidy is a hallmark of breast cancer; however, knowledge of how these complex genomic rearrangements evolve during tumorigenesis is limited. In this study, we developed a highly multiplexed single-nucleus sequencing method to investigate copy number evolution in patients with triple-negative breast cancer. ...
Aneuploidy is a hallmark of breast cancer; however, knowledge of how these complex genomic rearrangements evolve during tumorigenesis …
Genetics of breast and ovarian cancer.
Narod SA. Br Med Bull 1994 - Review. PMID 7987646
Women with breast cancer are at increased risk of developing a second primary cancer of the ovary; and relatives of women with breast or ovarian cancer are at roughly double the risk for either tumour. The most convincing evidence, however, for a common predisposition for breast and ovarian cancer comes from genetic linkage studies. ...
Women with breast cancer are at increased risk of developing a second primary cancer of the ovary; and relatives of women with bre
Breast cancer.
Newman LA. Surg Oncol Clin N Am 2014. PMID 24882356
Heterogeneity of breast cancer: The importance of interaction between different tumor cell populations.
Januškevičienė I and Petrikaitė V. Life Sci 2019 - Review. PMID 31669239
INTRODUCTION: Breast cancer is the most common cancer and the second leading cause of cancer-related death in women worldwide. Despite the early detection of breast cancer and increasing knowledge of its biology and chemo-resistance, metastatic breast cancer is largely incurable disease. ...
INTRODUCTION: Breast cancer is the most common cancer and the second leading cause of cancer-related death in women worldwide. Despit …
Breast cancer genetics: family history, heterogeneity, molecular genetic diagnosis, and genetic counselling.
Lynch HT and Lynch JF. Curr Probl Cancer 1996 - Review. PMID 8976406
Between 5% and 10% of breast cancer cases can be traced to primary genetic factors. Before the discovery of the BRCA1 and BRCA2 genes, if a first-degree relative in direct genetic lineage had hereditary breast cancer or hereditary breast-ovarian cancer syndrome, the best estimate of family members' genetic risk for breast cancer was 50%. ...This presentation focuses on the need for (a) compilation of a detailed family history of cancer of all anatomic sites; (b) understanding of the natural history of hereditary breast cancer and its heterogeneous forms and the pathobiology of hereditary breast cancer; and (c) preparation for performance of genetic counseling that is based on the results of DNA sequencing to detect genes related to cancer susceptibility. ...
Between 5% and 10% of breast cancer cases can be traced to primary genetic factors. Before the discovery of the BRCA1 and BRCA2 genes …
The genetics of breast cancer.
Black DM. Eur J Cancer 1994 - Review. PMID 7734207
48,423 results
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