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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 3
1994 7
1995 13
1996 13
1997 14
1998 21
1999 39
2000 34
2001 57
2002 49
2003 36
2004 47
2005 40
2006 49
2007 47
2008 36
2009 37
2010 38
2011 27
2012 31
2013 36
2014 40
2015 50
2016 39
2017 45
2018 34
2019 14
2020 0
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813 results
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Page 1
CD28 Costimulation: From Mechanism to Therapy.
Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA. Esensten JH, et al. Immunity. 2016 May 17;44(5):973-88. doi: 10.1016/j.immuni.2016.04.020. Immunity. 2016. PMID: 27192564 Free PMC article. Review.
T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.
Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. Hui E, et al. Science. 2017 Mar 31;355(6332):1428-1433. doi: 10.1126/science.aaf1292. Epub 2017 Mar 9. Science. 2017. PMID: 28280247 Free PMC article.
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Kamphorst AO, Wieland A, Nasti T, Yang S, Zhang R, Barber DL, Konieczny BT, Daugherty CZ, Koenig L, Yu K, Sica GL, Sharpe AH, Freeman GJ, Blazar BR, Turka LA, Owonikoko TK, Pillai RN, Ramalingam SS, Araki K, Ahmed R. Kamphorst AO, et al. Science. 2017 Mar 31;355(6332):1423-1427. doi: 10.1126/science.aaf0683. Epub 2017 Mar 9. Science. 2017. PMID: 28280249 Free PMC article.
Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells.
Kawalekar OU, O'Connor RS, Fraietta JA, Guo L, McGettigan SE, Posey AD Jr, Patel PR, Guedan S, Scholler J, Keith B, Snyder NW, Blair IA, Milone MC, June CH. Kawalekar OU, et al. Immunity. 2016 Feb 16;44(2):380-90. doi: 10.1016/j.immuni.2016.01.021. Immunity. 2016. PMID: 26885860 Free article.
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo.
Milone MC, Fish JD, Carpenito C, Carroll RG, Binder GK, Teachey D, Samanta M, Lakhal M, Gloss B, Danet-Desnoyers G, Campana D, Riley JL, Grupp SA, June CH. Milone MC, et al. Version 2. Mol Ther. 2009 Aug;17(8):1453-64. doi: 10.1038/mt.2009.83. Epub 2009 Apr 21. Mol Ther. 2009. PMID: 19384291 Free PMC article.
A human immunodeficiency syndrome caused by mutations in CARMIL2.
Schober T, Magg T, Laschinger M, Rohlfs M, Linhares ND, Puchalka J, Weisser T, Fehlner K, Mautner J, Walz C, Hussein K, Jaeger G, Kammer B, Schmid I, Bahia M, Pena SD, Behrends U, Belohradsky BH, Klein C, Hauck F. Schober T, et al. Nat Commun. 2017 Jan 23;8:14209. doi: 10.1038/ncomms14209. Nat Commun. 2017. PMID: 28112205 Free PMC article.
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.
Westra HJ, Martínez-Bonet M, Onengut-Gumuscu S, Lee A, Luo Y, Teslovich N, Worthington J, Martin J, Huizinga T, Klareskog L, Rantapaa-Dahlqvist S, Chen WM, Quinlan A, Todd JA, Eyre S, Nigrovic PA, Gregersen PK, Rich SS, Raychaudhuri S. Westra HJ, et al. Nat Genet. 2018 Oct;50(10):1366-1374. doi: 10.1038/s41588-018-0216-7. Epub 2018 Sep 17. Nat Genet. 2018. PMID: 30224649 Free PMC article.
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