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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1923 1
1931 1
1935 3
1936 3
1937 1
1938 4
1939 1
1940 1
1941 3
1942 1
1943 1
1945 5
1946 9
1947 16
1948 17
1949 14
1950 26
1951 29
1952 26
1953 45
1954 36
1955 50
1956 35
1957 59
1958 71
1959 77
1960 107
1961 106
1962 108
1963 207
1964 266
1965 295
1966 292
1967 309
1968 369
1969 383
1970 398
1971 405
1972 452
1973 420
1974 470
1975 659
1976 757
1977 821
1978 701
1979 815
1980 1006
1981 1040
1982 1227
1983 1362
1984 1550
1985 1777
1986 1872
1987 2026
1988 2211
1989 2701
1990 2829
1991 3092
1992 3469
1993 3622
1994 3996
1995 5233
1996 5932
1997 5892
1998 6748
1999 7606
2000 8430
2001 8862
2002 9955
2003 11136
2004 12363
2005 14052
2006 15318
2007 16617
2008 17292
2009 19141
2010 21955
2011 24522
2012 27486
2013 30390
2014 33099
2015 35063
2016 36350
2017 38862
2018 41801
2019 44697
2020 140471
2021 190167
2022 182398
2023 107564
2024 186

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1,037,382 results

Use COVID-19 filters from PubMed Clinical Queries to refine your search See more SARS-CoV-2 literature, sequence, and clinical content from NCBI

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Computational screening of antagonists against the SARS-CoV-2 (COVID-19) coronavirus by molecular docking.
Yu R, Chen L, Lan R, Shen R, Li P. Yu R, et al. Int J Antimicrob Agents. 2020 Aug;56(2):106012. doi: 10.1016/j.ijantimicag.2020.106012. Epub 2020 May 8. Int J Antimicrob Agents. 2020. PMID: 32389723 Free PMC article.
In the current spread of novel coronavirus (SARS-CoV-2), antiviral drug discovery is of great importance. AutoDock Vina was used to screen potential drugs by molecular docking with the structural protein and non-structural protein sites of new coronavirus. .. …
In the current spread of novel coronavirus (SARS-CoV-2), antiviral drug discovery is of great importance. AutoDock Vina was used to s …
Immune-Boosting, Antioxidant and Anti-inflammatory Food Supplements Targeting Pathogenesis of COVID-19.
Mrityunjaya M, Pavithra V, Neelam R, Janhavi P, Halami PM, Ravindra PV. Mrityunjaya M, et al. Front Immunol. 2020 Oct 7;11:570122. doi: 10.3389/fimmu.2020.570122. eCollection 2020. Front Immunol. 2020. PMID: 33117359 Free PMC article. Review.
The COVID-19 is an acute and contagious disease characterized by pneumonia and ARDS. ...Therefore, exploring the repurposing of natural compounds may provide alternatives against COVID-19. Several nutraceuticals have a proven ability of immune-boosting …
The COVID-19 is an acute and contagious disease characterized by pneumonia and ARDS. ...Therefore, exploring the repurposing o …
Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19.
Xu H, Li S, Liu J, Cheng J, Kang L, Li W, Zhong Y, Wei C, Fu L, Qi J, Zhang Y, You M, Zhou Z, Zhang C, Su H, Yao S, Zhou Z, Shi Y, Deng R, Lv Q, Li F, Qi F, Chen J, Zhang S, Ma X, Xu Z, Li S, Xu Y, Peng K, Shi Y, Jiang H, Gao GF, Huang L. Xu H, et al. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2301775120. doi: 10.1073/pnas.2301775120. Epub 2023 Apr 24. Proc Natl Acad Sci U S A. 2023. PMID: 37094153 Free PMC article.
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern, and effective antiviral reagents are urgently needed. ...These findings will greatly stimulate the study of TCMT-NDRD against COVID-19....
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern, and effective antiviral reagents …
Zinc and COVID-19: Basis of Current Clinical Trials.
Pal A, Squitti R, Picozza M, Pawar A, Rongioletti M, Dutta AK, Sahoo S, Goswami K, Sharma P, Prasad R. Pal A, et al. Biol Trace Elem Res. 2021 Aug;199(8):2882-2892. doi: 10.1007/s12011-020-02437-9. Epub 2020 Oct 22. Biol Trace Elem Res. 2021. PMID: 33094446 Free PMC article. Review.
Zinc, one of the anti-inflammatory and antioxidant micronutrient found in food with well-established role in immunity, is currently being used in some clinical trials against COVID-19. This review integrates the contemporary studies of role of zinc in anti …
Zinc, one of the anti-inflammatory and antioxidant micronutrient found in food with well-established role in immunity, is currently b …
Active vitamin D supplementation and COVID-19 infections: review.
Farid N, Rola N, Koch EAT, Nakhoul N. Farid N, et al. Ir J Med Sci. 2021 Nov;190(4):1271-1274. doi: 10.1007/s11845-020-02452-8. Epub 2021 Jan 6. Ir J Med Sci. 2021. PMID: 33409846 Free PMC article. Review.
SARS-CoV-2, causing the lethal disease COVid-19, is a public health emergency in the 2020 global pandemic. ...On the other hand, the efficacy of supplementation with active vitamin D, an immunomodulator hormone with antiinflammatory and antimicrobial e …
SARS-CoV-2, causing the lethal disease COVid-19, is a public health emergency in the 2020 global pandemic. ...On the other han …
Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study.
Xia L, Shi Y, Su J, Friedemann T, Tao Z, Lu Y, Ling Y, Lv Y, Zhao R, Geng Z, Cui X, Lu H, Schröder S. Xia L, et al. Phytomedicine. 2021 May;85:153390. doi: 10.1016/j.phymed.2020.153390. Epub 2020 Oct 22. Phytomedicine. 2021. PMID: 33158717 Free PMC article. Clinical Trial.
PURPOSE: To evaluate the antiviral and anti-inflammatory properties and to discover the mechanism of action of SFJDC as a potential drug for the treatment of COVID-19. ...It might be beneficial to start SFJDC treatment as early as possible in suspected cases …
PURPOSE: To evaluate the antiviral and anti-inflammatory properties and to discover the mechanism of action of SFJDC as a potential d …
Mechanistic Insights into the Pharmacological Significance of Silymarin.
Wadhwa K, Pahwa R, Kumar M, Kumar S, Sharma PC, Singh G, Verma R, Mittal V, Singh I, Kaushik D, Jeandet P. Wadhwa K, et al. Molecules. 2022 Aug 21;27(16):5327. doi: 10.3390/molecules27165327. Molecules. 2022. PMID: 36014565 Free PMC article. Review.
The contemporary literature reveals that silymarin is employed significantly as a neuroprotective, hepatoprotective, cardioprotective, antioxidant, anti-cancer, anti-diabetic, anti-viral, anti-hypertensive, immunomodulator, anti-inflammatory, photoprotective and det …
The contemporary literature reveals that silymarin is employed significantly as a neuroprotective, hepatoprotective, cardioprotective, an …
Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19.
Khazdair MR, Ghafari S, Sadeghi M. Khazdair MR, et al. Pharm Biol. 2021 Dec;59(1):696-703. doi: 10.1080/13880209.2021.1931353. Pharm Biol. 2021. PMID: 34110959 Free PMC article. Review.
CONTEXT: COVID-19 is a novel coronavirus that causes a severe infection in the respiratory system. ...Nigella sativa and TQ increased the serum levels of IgG1 and IgG2a, and improved pulmonary function tests in restrictive respiratory disorders. DISCUSSION AND CONCL …
CONTEXT: COVID-19 is a novel coronavirus that causes a severe infection in the respiratory system. ...Nigella sativa and TQ in …
Roles of flavonoids against coronavirus infection.
Russo M, Moccia S, Spagnuolo C, Tedesco I, Russo GL. Russo M, et al. Chem Biol Interact. 2020 Sep 1;328:109211. doi: 10.1016/j.cbi.2020.109211. Epub 2020 Jul 28. Chem Biol Interact. 2020. PMID: 32735799 Free PMC article. Review.
In terms of public health, the 21st century has been characterized by coronavirus pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2012 MERS-CoV emerged and in 2019 a new human betacoronavirus strain, called SARS-CoV-2, caused the unprecedented COVID-19 outb …
In terms of public health, the 21st century has been characterized by coronavirus pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2 …
Anti-coronavirus disease 2019 (COVID-19) targets and mechanisms of puerarin.
Qin X, Huang C, Wu K, Li Y, Liang X, Su M, Li R. Qin X, et al. J Cell Mol Med. 2021 Jan;25(2):677-685. doi: 10.1111/jcmm.16117. Epub 2020 Nov 26. J Cell Mol Med. 2021. PMID: 33241658 Free PMC article.
The present study aimed to uncover the pharmacological function and underlying mechanism of puerarin as a potential treatment for COVID-19, using an in silico methodology, including network pharmacology and molecular docking. ...Molecular doc …
The present study aimed to uncover the pharmacological function and underlying mechanism of puerarin as a potential treatment for COVID …
1,037,382 results
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