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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 2
1992 9
1993 22
1994 49
1995 69
1996 103
1997 121
1998 136
1999 164
2000 181
2001 207
2002 200
2003 157
2004 178
2005 215
2006 217
2007 215
2008 223
2009 257
2010 233
2011 230
2012 281
2013 303
2014 299
2015 380
2016 429
2017 490
2018 532
2019 254
2020 7
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5,670 results
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Page 1
CTLA-4: a moving target in immunotherapy.
Rowshanravan B, Halliday N, Sansom DM. Rowshanravan B, et al. Blood. 2018 Jan 4;131(1):58-67. doi: 10.1182/blood-2017-06-741033. Epub 2017 Nov 8. Blood. 2018. PMID: 29118008 Free PMC article. Review.
Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination.
Boutros C, Tarhini A, Routier E, Lambotte O, Ladurie FL, Carbonnel F, Izzeddine H, Marabelle A, Champiat S, Berdelou A, Lanoy E, Texier M, Libenciuc C, Eggermont AM, Soria JC, Mateus C, Robert C. Boutros C, et al. Nat Rev Clin Oncol. 2016 Aug;13(8):473-86. doi: 10.1038/nrclinonc.2016.58. Epub 2016 May 4. Nat Rev Clin Oncol. 2016. PMID: 27141885 Review.
Radiotherapy induces responses of lung cancer to CTLA-4 blockade.
Formenti SC, Rudqvist NP, Golden E, Cooper B, Wennerberg E, Lhuillier C, Vanpouille-Box C, Friedman K, Ferrari de Andrade L, Wucherpfennig KW, Heguy A, Imai N, Gnjatic S, Emerson RO, Zhou XK, Zhang T, Chachoua A, Demaria S. Formenti SC, et al. Nat Med. 2018 Dec;24(12):1845-1851. doi: 10.1038/s41591-018-0232-2. Epub 2018 Nov 5. Nat Med. 2018. PMID: 30397353 Free PMC article. Clinical Trial.
Genetic basis for clinical response to CTLA-4 blockade in melanoma.
Snyder A, Makarov V, Merghoub T, Yuan J, Zaretsky JM, Desrichard A, Walsh LA, Postow MA, Wong P, Ho TS, Hollmann TJ, Bruggeman C, Kannan K, Li Y, Elipenahli C, Liu C, Harbison CT, Wang L, Ribas A, Wolchok JD, Chan TA. Snyder A, et al. N Engl J Med. 2014 Dec 4;371(23):2189-2199. doi: 10.1056/NEJMoa1406498. Epub 2014 Nov 19. N Engl J Med. 2014. PMID: 25409260 Free PMC article.
Cancer immunotherapy using checkpoint blockade.
Ribas A, Wolchok JD. Ribas A, et al. Science. 2018 Mar 23;359(6382):1350-1355. doi: 10.1126/science.aar4060. Epub 2018 Mar 22. Science. 2018. PMID: 29567705 Review.
The blockade of immune checkpoints in cancer immunotherapy.
Pardoll DM. Pardoll DM. Nat Rev Cancer. 2012 Mar 22;12(4):252-64. doi: 10.1038/nrc3239. Nat Rev Cancer. 2012. PMID: 22437870 Free PMC article. Review.
Lessons from CTLA-4 deficiency and checkpoint inhibition.
Lo B, Abdel-Motal UM. Lo B, et al. Curr Opin Immunol. 2017 Dec;49:14-19. doi: 10.1016/j.coi.2017.07.014. Epub 2017 Aug 11. Curr Opin Immunol. 2017. PMID: 28806575 Review.
Confusing signals: recent progress in CTLA-4 biology.
Walker LS, Sansom DM. Walker LS, et al. Trends Immunol. 2015 Feb;36(2):63-70. doi: 10.1016/j.it.2014.12.001. Epub 2015 Jan 9. Trends Immunol. 2015. PMID: 25582039 Free PMC article. Review.
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