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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 21
1976 42
1977 68
1978 105
1979 130
1980 144
1981 162
1982 121
1983 187
1984 180
1985 177
1986 164
1987 188
1988 202
1989 165
1990 236
1991 196
1992 222
1993 228
1994 347
1995 348
1996 435
1997 407
1998 401
1999 387
2000 396
2001 351
2002 372
2003 384
2004 463
2005 689
2006 721
2007 529
2008 630
2009 600
2010 432
2011 496
2012 560
2013 682
2014 615
2015 659
2016 634
2017 607
2018 642
2019 555
2020 188
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Search Results

14,062 results
Results by year
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Page 1
Gut microbiome and cancer immunotherapy.
Li W, et al. Cancer Lett 2019 - Review. PMID 30684593 Free article.
Cancer immunotherapy has emerged as a promising way in the treatment of patients with cancer. Accumulating evidence supports that microbiome affects the therapeutic efficacy of cancer immunotherapy, particularly immune checkpoint inhibitors. Here, we discuss the mutual relationship among gut microbiome, cancer, immunity, and cancer immunotherapy, with a focus on immunotherapy. ...
Cancer immunotherapy has emerged as a promising way in the treatment of patients with cancer. Accumulating evidence supports t
ISG15 in cancer: Beyond ubiquitin-like protein.
Han HG, et al. Cancer Lett 2018 - Review. PMID 30213559
In this review, we highlight current knowledge in the molecular understanding and physiological relevance of ISG15 and ISGylation and discuss new insights into how ISG15 is implicated in the pathogenesis of cancer, which could contribute to therapeutic intervention in cancer....
In this review, we highlight current knowledge in the molecular understanding and physiological relevance of ISG15 and ISGylation and discus …
CRISPR-Cas9 for cancer therapy: Opportunities and challenges.
Chen M, et al. Cancer Lett 2019 - Review. PMID 30684591
CRISPR-Cas9 has shown great promise for the treatment of cancer. However, despite its advantages and tremendous potential, numerous challenges, such as fitness of edited cells, editing efficiency, delivery methods and potential off-target effects, remain to be solved for completely clinical application. Here, we present the potential applications and recent advances of CRISPR-Cas9 in cancer therapy, and discuss the challenges that might be encountered in clinical applications....
CRISPR-Cas9 has shown great promise for the treatment of cancer. However, despite its advantages and tremendous potential, numerous c …
Microbiota transplantation: Targeting cancer treatment.
Wu X, et al. Cancer Lett 2019. PMID 30905818
These fascinating findings evoke a possibility of manipulating gut microbiota to optimize anti-cancer treatment from bench to beside. ...The safety and efficacy of MT in cancer treatment are the core of translational research in this promising field, which inspire us to focus on the MT technology and mechanism of MT targeting anti-cancer treatment. ...
These fascinating findings evoke a possibility of manipulating gut microbiota to optimize anti-cancer treatment from bench to beside. …
Cancer-associated fibroblasts-derived IL-8 mediates resistance to cisplatin in human gastric cancer.
Zhai J, et al. Cancer Lett 2019. PMID 30978440 Free article.
Chemoresistance remains the major obstacle to achieve optimal prognosis in gastric cancer patients, and the underlying molecular mechanisms of cancer-associated fibroblasts (CAFs) in gastric cancer chemoresistance remain poorly understood. ...Our study provides a novel strategy to improve the chemotherapeutical efficacy and the prognosis of gastric cancer....
Chemoresistance remains the major obstacle to achieve optimal prognosis in gastric cancer patients, and the underlying molecular mech …
Genetically engineered Salmonella Typhimurium: Recent advances in cancer therapy.
Liang K, et al. Cancer Lett 2019 - Review. PMID 30753837
However, Salmonella-mediated cancer therapies have not achieved the expected success, except in animal experiments. Many problems remain to be solved to exploit more promising strategies for combatting cancer with Salmonella bacteria. Here, we summarize the promising studies regarding cancer therapy mediated by Salmonella bacteria and highlight the main mechanisms of Salmonella anti-tumor activities....
However, Salmonella-mediated cancer therapies have not achieved the expected success, except in animal experiments. Many problems rem …
Drug delivery systems targeting tumor-associated fibroblasts for cancer immunotherapy.
Liu M, et al. Cancer Lett 2019 - Review. PMID 30731107
These findings suggest that targeting TAFs is a promising strategy for improving cancer immunotherapy. Our previous studies have indicated the ability of therapeutic nanoparticles to distribute into, and deplete or inactivate TAFs. This approach is discussed in the context of developing specific and effective immunotherapies for cancer....
These findings suggest that targeting TAFs is a promising strategy for improving cancer immunotherapy. Our previous studies have indi …
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