Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2003 23
2004 76
2005 142
2006 132
2007 193
2008 232
2009 218
2010 178
2011 190
2012 95
2013 11
2014 13
2015 14
2016 12
2017 10
2018 7
2019 5
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

1,383 results
Results by year
Filters applied: . Clear all
Page 1
Endocannabinoid system in neurodegenerative disorders
Basavarajappa BS, et al. J Neurochem 2017 - Review. PMID 28608560 Free PMC article.
The endocannabinoid system, which involves cannabinoid receptors type 1 (CB1R) and type 2 (CB2R), endogenous cannabinoids and the enzymes that catabolize these compounds, has been shown to contribute to the development of NDDs in several animal models and human studies. ...
The endocannabinoid system, which involves cannabinoid receptors type 1 (CB1R) and type 2 (CB2R), endogenous cannabinoids and …
Cannabinoids and cancer pain: A new hope or a false dawn?
Brown MRD and Farquhar-Smith WP. Eur J Intern Med 2018 - Review. PMID 29482740
Cannabinoid receptors are expressed in the peripheral and central nervous system and on immune cells, all areas ideally suited to modulation of pain processing. ...The efficacy of cannabinoids seems to have been 'lost in translation' which may in part be related to using extracts of herbal cannabis rather than targeted selective full agonists at the cannabinoid CB1 and CB2 receptors....
Cannabinoid receptors are expressed in the peripheral and central nervous system and on immune cells, all areas ideally suited to mod
Metabolism of endocannabinoids
Biernacki M and Skrzydlewska E. Postepy Hig Med Dosw (Online) 2016 - Review. PMID 27516570
The primary role of endocannabinoids is the activation of cannabinoid receptors. Both AEA and 2-AG are primarily agonists of the CB1 receptor and to a lower degree CB2 and TRPV1r eceptors, but 2-AG has stronger affinity for these receptors. Through activation of receptors, endocannabinoids affect cellular metabolism and participate in the metabolic processes by receptor-independent pathways. ...
The primary role of endocannabinoids is the activation of cannabinoid receptors. Both AEA and 2-AG are primarily agonists of the CB1 …
Masturbation to Orgasm Stimulates the Release of the Endocannabinoid 2-Arachidonoylglycerol in Humans
Fuss J, et al. J Sex Med 2017. PMID 29110806
The role of endocannabinoids in mammalian sexual behavior has been suggested because of the influence of cannabinoid receptor agonists and antagonists on rodent sexual activity. ...
The role of endocannabinoids in mammalian sexual behavior has been suggested because of the influence of cannabinoid receptor
Human serum albumin: A modulator of cannabinoid drugs.
Leboffe L, et al. IUBMB Life 2017. PMID 28976704 Free article.
In recent years, several pharmacological tools to target endocannabinoid neurotransmission have been developed, including direct and indirect cannabinoid agonists and cannabinoid antagonists. ...In silico docking observations strongly indicate that HSA avidly binds the indirect cannabinoid agonists URB597, AM5206, JZL184, JZL195, and AM404, the direct cannabinoid agonists WIN55,212-2 and CP55,940, and the prototypical cannabinoid antagonist/inverse agonist SR141716. ...
In recent years, several pharmacological tools to target endocannabinoid neurotransmission have been developed, including direct and indirec …
Cannabinoids.
Grotenhermen F. Curr Drug Targets CNS Neurol Disord 2005 - Review. PMID 16266285
Besides phytocannabinoids of the cannabis plant, modulators of the cannabinoid system comprise synthetic agonists and antagonists at the CB receptors and inhibitors of endocannabinoid degradation. ...There is evidence for some non-receptor dependent mechanisms of cannabinoids and for endocannabinoid effects mediated by vanilloid receptors. ...
Besides phytocannabinoids of the cannabis plant, modulators of the cannabinoid system comprise synthetic agonists and antagoni …
The endocannabinoid system as an emerging target of pharmacotherapy
Pacher P, et al. Pharmacol Rev 2006 - Review. PMID 16968947 Free PMC article.
Such studies have been greatly facilitated by the introduction of selective cannabinoid receptor antagonists and inhibitors of endocannabinoid metabolism and transport, as well as mice deficient in cannabinoid receptors or the endocannabinoid-degrading enzyme fatty acid amidohydrolase. ...The use of selective CB(2) receptor agonists, which lack psychoactive properties, could represent another promising avenue for certain conditions. ...
Such studies have been greatly facilitated by the introduction of selective cannabinoid receptor antagonists and inhibitors of …
Endocannabinoid-mediated control of synaptic transmission
Kano M, et al. Physiol Rev 2009 - Review. PMID 19126760 Free article.
The discovery of cannabinoid receptors and subsequent identification of their endogenous ligands (endocannabinoids) in early 1990s have greatly accelerated research on cannabinoid actions in the brain. ...It is now well accepted that endocannabinoids are released from postsynaptic neurons, activate presynaptic cannabinoid CB(1) receptors, and cause transient and long-lasting reduction of neurotransmitter release. ...
The discovery of cannabinoid receptors and subsequent identification of their endogenous ligands (endocannabinoids) in early 1990s ha …
Endocannabinoids in liver disease
Tam J, et al. Hepatology 2011 - Review. PMID 21254182 Free PMC article.
Endocannabinoids are lipid mediators of the same cannabinoid (CB) receptors that mediate the effects of marijuana. The endocannabinoid system (ECS) consists of CB receptors, endocannabinoids, and the enzymes involved in their biosynthesis and degradation, and it is present in both brain and peripheral tissues, including the liver. ...
Endocannabinoids are lipid mediators of the same cannabinoid (CB) receptors that mediate the effects of marijuana. The endocannabinoi …
1,383 results
Jump to page
Feedback