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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 4
1946 5
1947 4
1948 2
1949 1
1950 2
1951 3
1952 2
1953 3
1954 4
1958 2
1960 1
1961 1
1962 2
1963 1
1964 2
1973 1
1974 2
1975 2
1976 36
1977 85
1978 79
1979 63
1980 78
1981 64
1982 46
1983 62
1984 59
1985 45
1986 51
1987 64
1988 46
1989 50
1990 58
1991 57
1992 45
1993 51
1994 43
1995 103
1996 83
1997 97
1998 177
1999 158
2000 173
2001 209
2002 254
2003 228
2004 199
2005 274
2006 231
2007 275
2008 297
2009 271
2010 271
2011 320
2012 363
2013 322
2014 395
2015 438
2016 492
2017 500
2018 494
2019 288
2020 15
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7,311 results
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Page 1
Cannabinoids in dermatology: a scoping review.
Eagleston LRM, et al. Dermatol Online J 2018 - Review. PMID 30142706 Free article.
A limited number of cannabinoid compounds have been approved for a specific set of conditions. However, the current role of cannabinoids for the treatment of dermatologic conditions remains to be defined. ...Cannabinoids have shown some initial promise as therapy for a variety of skin diseases. However, there is a requirement for thorough pre-clinical research and large-scale, randomized, controlled trials before cannabinoids can be considered safe and effective treatments for these conditions....
A limited number of cannabinoid compounds have been approved for a specific set of conditions. However, the current role of cannab
The pharmacokinetics and the pharmacodynamics of cannabinoids.
Lucas CJ, et al. Br J Clin Pharmacol 2018 - Review. PMID 30001569 Free PMC article.
There is increasing interest in the use of cannabinoids for disease and symptom management, but limited information available regarding their pharmacokinetics and pharmacodynamics to guide prescribers. ...The pharmacokinetics of cannabinoids and the effects observed depend on the formulation and route of administration, which should be tailored to individual patient requirements. ...
There is increasing interest in the use of cannabinoids for disease and symptom management, but limited information available regardi …
Medical Use of Cannabinoids.
Fraguas-Sánchez AI and Torres-Suárez AI. Drugs 2018 - Review. PMID 30374797
Cannabinoids have been tested in several cancer types, including brain, breast and prostate cancers. Cannabinoids have shown promise as analgesics for the treatment of both inflammatory and neuropathic pain. ...Considering the importance of the endocannabinoid system and the therapeutic potential of cannabinoids in this vast number of medical conditions, several clinical studies with cannabinoid-based medications are ongoing. ...
Cannabinoids have been tested in several cancer types, including brain, breast and prostate cancers. Cannabinoids have shown p
Cannabinoids: from pot to lab.
Papaseit E, et al. Int J Med Sci 2018 - Review. PMID 30275754 Free PMC article.
In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and the medical (pharmaceutical cannabinoids and medical cannabis) has been crossed. ...We have also analyzed serious adverse reactions and intoxications associated with the use of synthetic cannabinoids, as well as the latest developments in the research of pharmaceutical cannabinoids....
In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and …
Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science.
Baron EP. Headache 2018 - Review. PMID 30152161
Most of the existing literature reports on the cannabinoids Δ(9) -tetrahydrocannabinol (THC) and cannabidiol (CBD), or cannabis in general. There are many cannabis strains that vary widely in the composition of cannabinoids, terpenes, flavonoids, and other compounds. ...
Most of the existing literature reports on the cannabinoids Δ(9) -tetrahydrocannabinol (THC) and cannabidiol (CBD), or cannabis in ge …
Cannabinoids for Treatment of MS Symptoms: State of the Evidence.
Rice J and Cameron M. Curr Neurol Neurosci Rep 2018 - Review. PMID 29923025
This paper provides an overview of the available cannabinoid-based formulations, a summary of the highest quality evidence for the use of cannabinoids for treating spasticity and pain associated with multiple sclerosis (MS), and a discussion of possible dosing regimens based on information from these studies. ...The medical use of cannabinoids remains controversial. While cannabinoids have been studied for a variety of neurologic disorders, there is strongest evidence to indicate benefits in treatment of spasticity and neuropathic pain in multiple sclerosis. ...
This paper provides an overview of the available cannabinoid-based formulations, a summary of the highest quality evidence for the us …
Cannabinoids in depressive disorders.
Poleszak E, et al. Life Sci 2018 - Review. PMID 30290188
Benefits from use of cannabinoid agents in epilepsy, multiple sclerosis, Parkinson's disease, Alzheimer's disease, and others have been suggested. ...Responses to the cannabinoid agents are relatively fast, and most probably, the noradrenergic, serotoninergic, glutamatergic neurotransmission, neuroprotective activity, as well as modulation of the hypothalamic-pituitary-adrenal axis are implicated in the observed effects. ...
Benefits from use of cannabinoid agents in epilepsy, multiple sclerosis, Parkinson's disease, Alzheimer's disease, and others have be …
Synthetic cannabinoids are substrates and inhibitors of multiple drug-metabolizing enzymes.
Kong TY, et al. Arch Pharm Res 2018 - Review. PMID 30039377
The inhibitory effects of synthetic cannabinoids on CYP and UGT activities are also reviewed to predict the potential of synthetic cannabinoids for drug-drug interactions. The drug-metabolizing enzymes responsible for metabolism of synthetic cannabinoids should be characterized and the effects of synthetic cannabinoids on CYP and UGT activities should be determined to predict the pharmacokinetics of synthetic cannabinoids and synthetic cannabinoid-induced drug-drug interactions in the clinic....
The inhibitory effects of synthetic cannabinoids on CYP and UGT activities are also reviewed to predict the potential of synthetic …
The effects of cannabinoids on the endocrine system.
Borowska M, et al. Endokrynol Pol 2018 - Review. PMID 30618031 Free article.
Cannabinoids are the derivatives of the cannabis plant, the most potent bioactive component of which is tetrahydrocannabinol (THC). The most commonly used drugs containing cannabinoids are marijuana, hashish, and hashish oil. These compounds exert their effects via interaction with the cannabinoid receptors CB1 and CB2. ...
Cannabinoids are the derivatives of the cannabis plant, the most potent bioactive component of which is tetrahydrocannabinol (THC). T
Complete biosynthesis of cannabinoids and their unnatural analogues in yeast.
Luo X, et al. Nature 2019. PMID 30814733
Certain cannabinoid formulations have been approved as prescription drugs in several countries for the treatment of a range of human ailments(3). However, the study and medicinal use of cannabinoids has been hampered by the legal scheduling of Cannabis, the low in planta abundances of nearly all of the dozens of known cannabinoids(4), and their structural complexity, which limits bulk chemical synthesis. ...
Certain cannabinoid formulations have been approved as prescription drugs in several countries for the treatment of a range of human …
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