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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 6
1972 11
1973 18
1974 14
1975 13
1976 14
1977 19
1978 16
1979 26
1980 26
1981 28
1982 23
1983 20
1984 23
1985 22
1986 21
1987 25
1988 10
1989 16
1990 11
1991 20
1992 9
1993 8
1994 9
1995 27
1996 25
1997 18
1998 17
1999 15
2000 19
2001 29
2002 36
2003 39
2004 43
2005 43
2006 56
2007 56
2008 79
2009 64
2010 72
2011 95
2012 105
2013 107
2014 117
2015 153
2016 164
2017 180
2018 185
2019 96
2020 4
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2,021 results
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Page 1
Adverse Effects of Synthetic Cannabinoids: Management of Acute Toxicity and Withdrawal.
Cooper ZD. Curr Psychiatry Rep 2016 - Review. PMID 27074934 Free PMC article.
Although several chemical structural classes of synthetic cannabinoids (SCs) were recently classified as Schedule I substances, rates of use and cases of serious toxic effects remain high. ...In order to determine prevalence of use in cannabis smokers, a population at high risk for SC use, we obtained data on demographics of SC users, frequency of use, and adverse effects over a 3.5-year period (2012-2015) in the New York City metropolitan area, a region with a recent history of high SC use. ...
Although several chemical structural classes of synthetic cannabinoids (SCs) were recently classified as Schedule I substances, rates …
Clinical and Preclinical Evidence for Functional Interactions of Cannabidiol and Δ9-Tetrahydrocannabinol
Boggs DL, et al. Neuropsychopharmacology 2018 - Review. PMID 28875990 Free PMC article.
THC is thought to produce the main psychoactive effects of cannabis, while CBD does not appear to have similar effects. Studies conflict as to whether CBD attenuates or exacerbates the behavioral and cognitive effects of THC. ...Both THC and CBD, as well as other cannabinoid molecules, are currently being evaluated for medicinal purposes, separately and in combination. ...
THC is thought to produce the main psychoactive effects of cannabis, while CBD does not appear to have similar effects. Studie …
Cannabinoids for Treatment of MS Symptoms: State of the Evidence.
Rice J and Cameron M. Curr Neurol Neurosci Rep 2018 - Review. PMID 29923025
Adverse events in studies were generally more common in the groups using cannabinoid products but serious adverse events were rare and cannabis products were generally well-tolerated. Cannabis use does appear to be associated with increased risk of certain adverse events, including psychosis, cardiovascular diseases, and cannabinoid hyperemesis syndrome....
Adverse events in studies were generally more common in the groups using cannabinoid products but serious adverse event
Cannabis, cannabinoids, and health.
Lafaye G, et al. Dialogues Clin Neurosci 2017 - Review. PMID 29302228 Free PMC article.
Though it was long considered to be a "soft" drug, studies have proven the harmful psychiatric and addictive effects associated with its use. A number of elements are responsible for the increased complications of cannabis use, including the increase in the potency of cannabis and an evolution in the ratio between the two primary components, Δ(9)-tetrahydrocannabinol (Δ(9)-THC) and cannabidiol (toward a higher proportion of Δ(9)-THC), Synthetic cannabinoid (SC) use has rapidly progressed over the last few years, primarily among frequent cannabis users, because SCs provide similar psychoactive effects to cannabis. ...
Though it was long considered to be a "soft" drug, studies have proven the harmful psychiatric and addictive effects associated with …
Spicing Up Pharmacology: A Review of Synthetic Cannabinoids From Structure to Adverse Events.
Davidson C, et al. Adv Pharmacol 2017 - Review. PMID 28826533
Recreational use of synthetic cannabinoids (SCB), a class of novel psychoactive substances is an increasing public health problem specifically in Western societies, with teenagers, young adults, and the prison population being the most affected. ...Finally, we highlight the psychological effects of SCB, particularly on learning and memory, and adverse clinical effects including on the cardiovascular system, kidneys, and CNS, including psychosis. ...
Recreational use of synthetic cannabinoids (SCB), a class of novel psychoactive substances is an increasing public health problem spe …
Toxicology of Marijuana, Synthetic Cannabinoids, and Cannabidiol in Dogs and Cats.
Brutlag A and Hommerding H. Vet Clin North Am Small Anim Pract 2018 - Review. PMID 30342565
In addition, exposure to illegal synthetic cannabinoids remains concerning. Veterinarians need to be able to recognize associated clinical signs and understand when cases have the potential for severity. ...
In addition, exposure to illegal synthetic cannabinoids remains concerning. Veterinarians need to be able to recognize associated cli …
Pro-psychotic effects of synthetic cannabinoids: interactions with central dopamine, serotonin, and glutamate systems.
Fantegrossi WE, et al. Drug Metab Rev 2018 - Review. PMID 29385930 Free PMC article.
An association between marijuana use and schizophrenia has been noted for decades, and the recent emergence of high-efficacy synthetic cannabinoids (SCBs) as drugs of abuse has lead to a growing number of clinical reports of persistent psychotic effects in users of these substances. The mechanisms underlying SCB-elicited pro-psychotic effects is unknown, but given the ubiquitous neuromodulatory functions of the endocannabinoid system, it seems likely that agonist actions at cannabinoid type-1 receptors (CB1Rs) might modulate the functions of other neurotransmitter systems known to be involved in schizophrenia. ...
An association between marijuana use and schizophrenia has been noted for decades, and the recent emergence of high-efficacy synthetic ca
Cannabinoids and Psychosis.
D'Souza DC, et al. Curr Pharm Des 2016 - Review. PMID 27568729
The link between cannabinoids and psychosis is greater with earlier age of exposure to cannabinoids, childhood abuse and genetic vulnerability. However, cannabinoids are neither necessary nor sufficient to cause a persistent psychotic disorder. More likely cannabinoids are a 'component cause' interacting with other known (family history) and unknown factors to result in psychosis outcomes. ...
The link between cannabinoids and psychosis is greater with earlier age of exposure to cannabinoids, childhood abuse and genet …
The adverse health effects of synthetic cannabinoids with emphasis on psychosis-like effects.
van Amsterdam J, et al. J Psychopharmacol 2015 - Review. PMID 25586398
This paper reviews the general toxicity profile and the adverse effects of SCRAs with special emphasis on their psychosis-inducing risk. The review shows that, compared with the use of natural cannabis, the use of SCRAs may cause more frequent and more severe unwanted negative effects, especially in younger, inexperienced users. ...
This paper reviews the general toxicity profile and the adverse effects of SCRAs with special emphasis on their psychosis-indu …
Cannabinoids for fibromyalgia.
Walitt B, et al. Cochrane Database Syst Rev 2016 - Review. PMID 27428009 Free PMC article.
The most frequent adverse events were dizziness, nausea, dry mouth and drowsiness (six participants with nabilone). Neither study reported serious adverse events during the period of both studies. ...We found no relevant study with herbal cannabis, plant-based cannabinoids or synthetic cannabinoids other than nabilone in fibromyalgia. ...
The most frequent adverse events were dizziness, nausea, dry mouth and drowsiness (six participants with nabilone). Neither study rep …
2,021 results
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