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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1975 13
1976 12
1977 7
1978 12
1979 21
1980 30
1981 26
1982 15
1983 17
1984 8
1985 11
1986 13
1987 7
1988 4
1989 12
1990 6
1991 12
1992 6
1993 10
1994 10
1995 17
1996 15
1997 22
1998 25
1999 22
2000 34
2001 39
2002 61
2003 65
2004 76
2005 81
2006 75
2007 82
2008 81
2009 76
2010 90
2011 111
2012 139
2013 144
2014 169
2015 217
2016 225
2017 239
2018 278
2019 154
2020 6
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2,497 results
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Page 1
Therapeutic applications of cannabinoids.
Maurya N and Velmurugan BK. Chem Biol Interact 2018 - Review. PMID 30040916
The psychoactive property of cannabinoids is well known and there has been a continuous controversy regarding the usage of these compounds for therapeutic purposes all over the world. ...Thus, this work is an attempt to make the readers understand the positive implications of these compounds and indicates the significant developments of utilizing cannabinoids as therapeutic agents....
The psychoactive property of cannabinoids is well known and there has been a continuous controversy regarding the usage of these comp …
The therapeutic effects of Cannabis and cannabinoids: An update from the National Academies of Sciences, Engineering and Medicine report.
Abrams DI. Eur J Intern Med 2018 - Review. PMID 29325791
Primacy was given to recently published systematic reviews and primary research that studied one of the committee's 11 prioritized health endpoints- therapeutic effects; cancer incidence; cardiometabolic risk; respiratory disease; immune function; injury and death; prenatal, perinatal and postnatal outcomes; psychosocial outcomes; mental health; problem Cannabis use; and Cannabis use and abuse of other substances. The committee developed standard language to categorize the weight of evidence regarding whether Cannabis or cannabinoids use for therapeutic purposes are an effective or ineffective treatment for the prioritized health endpoints of interest. ...
Primacy was given to recently published systematic reviews and primary research that studied one of the committee's 11 prioritized health en …
The Use of Cannabis and Cannabinoids in Treating Symptoms of Multiple Sclerosis: a Systematic Review of Reviews.
Nielsen S, et al. Curr Neurol Neurosci Rep 2018 - Review. PMID 29442178
PURPOSE OF REVIEW: Pharmaceutical cannabinoids such as nabiximols, nabilone and dronabinol, and plant-based cannabinoids have been investigated for their therapeutic potential in treating multiple sclerosis (MS) symptoms. ...Recent high quality reviews find cannabinoids may have modest effects in MS for pain or spasticity. Future research should include studies with non-cannabinoid comparators; this is an important gap in the evidence....
PURPOSE OF REVIEW: Pharmaceutical cannabinoids such as nabiximols, nabilone and dronabinol, and plant-based cannabinoids have …
Cannabis and Cannabinoids for Chronic Pain.
Romero-Sandoval EA, et al. Curr Rheumatol Rep 2017 - Review. PMID 28983880
PURPOSE OF REVIEW: The purpose of this study was to provide the most up-to-date scientific evidence of the potential analgesic effects, or lack thereof, of the marijuana plant (cannabis) or cannabinoids, and of safety or tolerability of their long-term use. ...Continued research on cannabis constituents and improving bioavailability for oral cannabinoids is needed. Other aspects of pain management in patients using cannabis require further open discussion: concomitant opioid use, medical vs. recreational cannabis, abuse potential, etc....
PURPOSE OF REVIEW: The purpose of this study was to provide the most up-to-date scientific evidence of the potential analgesic effects, or l …
Cannabinoids in dermatology: a scoping review.
Eagleston LRM, et al. Dermatol Online J 2018 - Review. PMID 30142706 Free article.
The therapeutic applications of cannabis and cannabinoids are an increasingly conspicuous topic as de-criminalization and legalization of these products continues to expand. A limited number of cannabinoid compounds have been approved for a specific set of conditions. However, the current role of cannabinoids for the treatment of dermatologic conditions remains to be defined. ...
The therapeutic applications of cannabis and cannabinoids are an increasingly conspicuous topic as de-criminalization and lega …
Adverse health effects of marijuana use.
Volkow ND, et al. N Engl J Med 2014 - Review. PMID 24897085 Free PMC article.
Cannabis in cancer care
Abrams DI and Guzman M. Clin Pharmacol Ther 2015 - Review. PMID 25777363 Free article.
Cannabinoids, the active components of Cannabis sativa, mimic the effects of the endogenous cannabinoids (endocannabinoids), activating specific cannabinoid receptors, particularly CB1 found predominantly in the central nervous system and CB2 found predominantly in cells involved with immune function. ...Cannabinoids have a favorable drug safety profile, but their medical use is predominantly limited by their psychoactive effects and their limited bioavailability....
Cannabinoids, the active components of Cannabis sativa, mimic the effects of the endogenous cannabinoids (endocannabinoids), a
Cannabidiol: State of the art and new challenges for therapeutic applications.
Pisanti S, et al. Pharmacol Ther 2017 - Review. PMID 28232276
Over the past years, several lines of evidence support a therapeutic potential of Cannabis derivatives and in particular phytocannabinoids. ...In this review, we highlight the pharmacological activities of CBD, its cannabinoid receptor-dependent and -independent action, its biological effects focusing on immunomodulation, angiogenetic properties, and modulation of neuronal and cardiovascular function. ...
Over the past years, several lines of evidence support a therapeutic potential of Cannabis derivatives and in particular phytocannabi …
Cannabinoids in cancer treatment: Therapeutic potential and legislation.
Dariš B, et al. Bosn J Basic Med Sci 2019 - Review. PMID 30172249 Free PMC article.
We also reviewed the current legislative updates on the use of cannabinoids for medical and therapeutic purposes, primarily in the EU countries. ...The national legislation of the EU Member States defines the legal boundaries of permissible use of cannabinoids for medical and therapeutic purposes, however, these legislative guidelines may not be aligned with the current scientific knowledge....
We also reviewed the current legislative updates on the use of cannabinoids for medical and therapeutic purposes, prima …
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