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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1952 2
1953 2
1954 5
1955 6
1956 5
1957 12
1958 10
1959 8
1960 10
1961 6
1962 19
1963 21
1964 30
1965 38
1966 36
1967 60
1968 47
1969 45
1970 75
1971 73
1972 75
1973 81
1974 78
1975 64
1976 60
1977 68
1978 99
1979 82
1980 100
1981 115
1982 128
1983 112
1984 145
1985 155
1986 189
1987 183
1988 190
1989 196
1990 252
1991 175
1992 176
1993 170
1994 159
1995 206
1996 158
1997 152
1998 162
1999 178
2000 151
2001 170
2002 173
2003 180
2004 205
2005 240
2006 248
2007 237
2008 209
2009 217
2010 260
2011 241
2012 267
2013 301
2014 286
2015 299
2016 283
2017 282
2018 290
2019 149
2020 1
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8,555 results
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Page 1
l-Carnitine Supplementation in Recovery after Exercise.
Fielding R, et al. Nutrients 2018 - Review. PMID 29534031 Free PMC article.
Given its pivotal role in fatty acid oxidation and energy metabolism, l-carnitine has been investigated as ergogenic aid for enhancing exercise capacity in the healthy athletic population. ...Later studies point to the positive impact of dietary supplementation with l-carnitine on the recovery process after exercise. ...
Given its pivotal role in fatty acid oxidation and energy metabolism, l-carnitine has been investigated as ergogenic aid for enhancin …
l-Carnitine and heart disease.
Wang ZY, et al. Life Sci 2018 - Review. PMID 29241711
These favorable effects of l-carnitine have been evident in infants, juvenile, young, adult and aged patients of sudden and chronic heart failure as well. This review describes the mechanism of action, metabolism and pharmacokinetics of l-carnitine. It specifically emphasizes upon the beneficial role of l-carnitine in cardiomyopathy....
These favorable effects of l-carnitine have been evident in infants, juvenile, young, adult and aged patients of sudden and chronic h …
Significance of l-carnitine for human health.
Adeva-Andany MM, et al. IUBMB Life 2017 - Review. PMID 28653367 Free article.
Carnitine acyltransferases catalyze the reversible transfer of acyl groups from acyl-coenzyme A esters to l-carnitine, forming acyl-carnitine esters that may be transported across cell membranes. l-Carnitine is a wáter-soluble compound that humans may obtain both by food ingestion and endogenous synthesis from trimethyl-lysine. ...Carnitine acyl-carnitine translocase transports acyl-carnitine esters across the inner mitochondrial membrane in exchange for free l-carnitine that exits the mitochondrial matrix. ...
Carnitine acyltransferases catalyze the reversible transfer of acyl groups from acyl-coenzyme A esters to l-carnitine, forming
Carnitine Inborn Errors of Metabolism.
Almannai M, et al. Molecules 2019 - Review. PMID 31500110 Free PMC article.
Renal carnitine reabsorption along with dietary intake and endogenous production maintain carnitine homeostasis. The precursors for carnitine biosynthesis are lysine and methionine. ...Carnitine inborn errors of metabolism could result from defects in carnitine biosynthesis, carnitine transport, or mitochondrial carnitine-acylcarnitine cycle. ...
Renal carnitine reabsorption along with dietary intake and endogenous production maintain carnitine homeostasis. The precursor …
Functional and molecular studies in primary carnitine deficiency.
Frigeni M, et al. Hum Mutat 2017. PMID 28841266 Free PMC article.
Primary carnitine deficiency is caused by a defect in the OCTN2 carnitine transporter encoded by the SLC22A5 gene. It can cause hypoketotic hypoglycemia or cardiomyopathy in children, and sudden death in children and adults. Fibroblasts from affected patients have reduced carnitine transport. We evaluated carnitine transport in fibroblasts from 358 subjects referred for possible carnitine deficiency. ...
Primary carnitine deficiency is caused by a defect in the OCTN2 carnitine transporter encoded by the SLC22A5 gene. It can caus …
L-carnitine treatment of insulin resistance: A systematic review and meta-analysis.
Xu Y, et al. Adv Clin Exp Med 2017 - Review. PMID 28791854 Free article.
CONCLUSIONS: L-carnitine was useful in treating patients with IR. L-carnitine can treat IR more effectively with prolonging the medication time. However, more RCTs with long-term L-carnitine treatment of IR are needed to confirm the viewpoint....
CONCLUSIONS: L-carnitine was useful in treating patients with IR. L-carnitine can treat IR more effectively with prolonging th …
Role of L-carnitine in female infertility.
Agarwal A, et al. Reprod Biol Endocrinol 2018 - Review. PMID 29373970 Free PMC article.
BACKGROUND: L-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regulate the oxidative and metabolic status of the female reproductive system. ...
BACKGROUND: L-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regul …
Acetyl-l-carnitine deficiency in patients with major depressive disorder.
Nasca C, et al. Proc Natl Acad Sci U S A 2018 - Clinical Trial. PMID 30061399 Free PMC article.
The endogenously produced molecule acetyl-l-carnitine (LAC) is critical for hippocampal function and several behavioral domains. ...We found that LAC levels, and not those of free carnitine, were decreased in patients with MDD compared with age- and sex-matched healthy controls in two independent study centers. ...
The endogenously produced molecule acetyl-l-carnitine (LAC) is critical for hippocampal function and several behavioral domains. ...W …
A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D.
Belsky JB, et al. Nutr Res Rev 2018 - Review. PMID 29984680
In the present review, we will evaluate the potential role of micronutrients in sepsis, specifically, thiamine, l-carnitine, vitamin C, Se and vitamin D. ...Based on the current available data, we conclude that thiamine may be considered in all septic patients at risk for thiamine deficiency and l-carnitine and vitamin C to those in septic shock. ...
In the present review, we will evaluate the potential role of micronutrients in sepsis, specifically, thiamine, l-carnitine, vitamin …
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