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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 10
1966 13
1967 12
1968 6
1969 8
1970 14
1971 12
1972 6
1973 4
1974 3
1975 3
1976 4
1977 6
1978 8
1979 8
1980 15
1981 22
1982 20
1983 21
1984 29
1985 20
1986 36
1987 33
1988 47
1989 51
1990 64
1991 47
1992 63
1993 58
1994 54
1995 42
1996 36
1997 47
1998 43
1999 37
2000 38
2001 54
2002 61
2003 52
2004 62
2005 79
2006 81
2007 71
2008 71
2009 59
2010 70
2011 84
2012 56
2013 88
2014 85
2015 89
2016 66
2017 80
2018 67
2019 32
2020 0
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2,071 results
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Page 1
L-carnitine--metabolic functions and meaning in humans life.
Pekala J, et al. Curr Drug Metab 2011 - Review. PMID 21561431
L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine into the diet. ...Further research is warranted in order to evaluate the biochemical, pharmacological, and physiological determinants of the response to carnitine supplementation, as well as to determine the potential benefits of carnitine supplements in selected categories of individuals who do not have fatty acid oxidation defects....
L-Carnitine can also be found in many foods, but red meats, such as beef and lamb, are the best choices for adding carnitine i …
The neurobiology of acetyl-L-carnitine.
Traina G. Front Biosci (Landmark Ed) 2016 - Review. PMID 27100509
A large body of evidence points to the positive effects of dietary supplementation of acetyl-L-carnitine (ALC). Its use has shown health benefits in neuroinflammation, which is a common denominator in a host of neurodegenerative diseases. ALC is the principal acetyl ester of L-Carnitine (LC), and it plays an essential role in intermediary metabolism, acting as a donor of acetyl groups and facilitating the transfer of fatty acids from cytosol to mitochondria during beta-oxidation. ...
A large body of evidence points to the positive effects of dietary supplementation of acetyl-L-carnitine (ALC). Its use has shown hea …
Supplementation of L-carnitine in athletes: does it make sense?
Karlic H and Lohninger A. Nutrition 2004 - Review. PMID 15212755
Studies in athletes have shown that carnitine supplementation may foster exercise performance. As reported in the majority of studies, an increase in maximal oxygen consumption and a lowering of the respiratory quotient indicate that dietary carnitine has the potential to stimulate lipid metabolism. ...As recently shown, carnitine has direct effects in regulation of gene expression (i.e., carnitine-acyltransferases) and may also exert effects via modulating intracellular fatty acid concentration. ...
Studies in athletes have shown that carnitine supplementation may foster exercise performance. As reported in the majority of studies …
Carnitine induces autophagy and restores high-fat diet-induced mitochondrial dysfunction.
Choi JW, et al. Metabolism 2018. PMID 28966077
As carnitine treatment is well known to improve insulin resistance by promoting mitochondrial function, we investigated if carnitine affects autophagy in the skeletal muscle of a high-fat diet-induced rodent model of obesity. ...In C2C12 myotubes, prolonged treatment with palmitate suppressed autophagy, which was relieved by carnitine treatment. However, the induction of autophagy by carnitine in C2C12 myotubes was not observed after knock-down of peroxisome proliferator-activated receptor γ (PPARγ), which is known to regulate autophagy. ...
As carnitine treatment is well known to improve insulin resistance by promoting mitochondrial function, we investigated if carniti
Carnitine.
Odle J, et al. Adv Nutr 2014. PMID 24829475 Free PMC article.
l-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function.
Sawicka AK, et al. Nutrients 2018 - Clinical Trial. PMID 29473908 Free PMC article.
In the blood samples, free carnitine, interleukin-6, tumor necrosis factor-α, C-reactive protein and IGF-1 were determined. A marked increase in free plasma carnitine concentration was observed due to l-carnitine supplementation. ...Positive and negative aspects of l-carnitine supplementation need to be clarified....
In the blood samples, free carnitine, interleukin-6, tumor necrosis factor-α, C-reactive protein and IGF-1 were determined. A marked …
L-Carnitine as an additive in Tyrode's buffer during platelet storage.
Mithun M and Rajashekaraiah V. Blood Coagul Fibrinolysis 2018. PMID 29995655
Protein carbonyls were maintained in L-carnitine groups. Catalase activity and total antioxidant capacity increased gradually. ...However, pH results emphasize that platelets with L-carnitine (50 mmol/l) could be stored up to 8 days. Therefore, Tyrode's buffer with L-carnitine can be an effective storage solution for extended platelet storage. ...
Protein carbonyls were maintained in L-carnitine groups. Catalase activity and total antioxidant capacity increased gradually. ...How …
[The effect of L-carnitine on the apoptosis of human lens epithelial cells through endoplasmic reticulum stress].
Kong DQ, et al. Zhonghua Yan Ke Za Zhi 2018. PMID 29747368 Chinese.
Cells were divided into four groups: H(2)O(2) group, L-carnitine (100 μmol/L) with H(2)O(2) group, phosphate buffered saline (PBS) group and L-carnitine (100 μmol/L) group. ...Flow cytometry results of the H(2)O(2) group, L-carnitine with H(2)O(2) group, PBS group and L-carnitine group were 31.4%±4.5%, 16.5%±2.8%, 2.1%±0.2% and 1.9%±1.8%, respectively (F=126.784, P=0.024) . ...
Cells were divided into four groups: H(2)O(2) group, L-carnitine (100 μmol/L) with H(2)O(2) group, phosphate buffered saline (PBS) gr …
Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio.
Li JM, et al. Sci Rep 2017. PMID 28102299 Free PMC article.
L-carnitine significantly decreased the lipid content in liver and muscle, accompanied by increased concentrations of total and free carnitine in tissues. ...However, the L-carnitine-enhanced lipid catabolism would cause a decrease in glucose utilization. Therefore, L-carnitine has comprehensive effects on nutrient metabolism in fish....
L-carnitine significantly decreased the lipid content in liver and muscle, accompanied by increased concentrations of total and free …
L-carnitine counteracts prepubertal exposure to cisplatin induced impaired sperm in adult rats by preventing germ cell apoptosis.
Yaman O and Topcu-Tarladacalisir Y. Biotech Histochem 2018. PMID 29388451
L-carnitine was injected 1 h before cisplatin administration and for the following 3 days for the cisplatin + carnitine group. ...L-carnitine treatment reduced testicular damage and the number of TUNEL positive cells significantly, while the number of PCNA positive cells in the cisplatin + carnitine group increased compared to the cisplatin group. ...
L-carnitine was injected 1 h before cisplatin administration and for the following 3 days for the cisplatin + carnitine group. …
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