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The APC/C activator FZR1 is essential for meiotic prophase I in mice.
Holt JE, Pye V, Boon E, Stewart JL, García-Higuera I, Moreno S, Rodríguez R, Jones KT, McLaughlin EA. Holt JE, et al. Development. 2014 Mar;141(6):1354-65. doi: 10.1242/dev.104828. Epub 2014 Feb 19. Development. 2014. PMID: 24553289 Free article.
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair.
Shenoy TR, Boysen G, Wang MY, Xu QZ, Guo W, Koh FM, Wang C, Zhang LZ, Wang Y, Gil V, Aziz S, Christova R, Rodrigues DN, Crespo M, Rescigno P, Tunariu N, Riisnaes R, Zafeiriou Z, Flohr P, Yuan W, Knight E, Swain A, Ramalho-Santos M, Xu DY, de Bono J, Wu H. Shenoy TR, et al. Ann Oncol. 2017 Jul 1;28(7):1495-1507. doi: 10.1093/annonc/mdx165. Ann Oncol. 2017. PMID: 28383660 Free PMC article.