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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 4
1989 13
1990 41
1991 63
1992 55
1993 88
1994 82
1995 92
1996 108
1997 117
1998 131
1999 134
2000 131
2001 104
2002 118
2003 130
2004 140
2005 165
2006 136
2007 133
2008 103
2009 135
2010 115
2011 113
2012 80
2013 88
2014 64
2015 51
2016 34
2017 30
2018 32
2019 12
2020 0
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2,676 results
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Page 1
Cell adhesion properties of human defensins.
Howell K and de Leeuw E. Biochem Biophys Res Commun 2018. PMID 29800568
In this study, we describe the effect on cell morphology and cell adhesion of human defensins. We find that Human Defensin 5, the major product of specialized gut epithelial cells, causes changes in cell morphology. HD-5 induces cell adhesion, binds to fibronectin and facilitates binding of T cells to intestinal epithelial cells. These effects were found also for a second prominent defensing, termed Human Neutrophil peptide-1, but not for other human defensins....
In this study, we describe the effect on cell morphology and cell adhesion of human defensins. We find that Human Defen …
PSGL-1: A New Player in the Immune Checkpoint Landscape
Tinoco R, et al. Trends Immunol 2017 - Review. PMID 28262471 Free PMC article.
P-selectin glycoprotein ligand-1 (PSGL-1) has long been studied as an adhesion molecule involved in immune cell trafficking and is recognized as a regulator of many facets of immune responses by myeloid cells. PSGL-1 also regulates T cell migration during homeostasis and inflammatory settings. However, recent findings indicate that PSGL-1 can also negatively regulate T cell function. ...
P-selectin glycoprotein ligand-1 (PSGL-1) has long been studied as an adhesion molecule involved in immune cell trafficking an …
Glycosylation in cancer: Selected roles in tumour progression, immune modulation and metastasis
Rodrigues JG, et al. Cell Immunol 2018 - Review. PMID 29576316
Metastasis is an intricate multi-step process that requires the acquisition of several cancer cell features, including the modulation of tumour cell migration, adhesion, invasion, and immune evasion. ...Glycans have major impact on cellular signalling and on the regulation of tumour cell-cell adhesion and cell-matrix interaction. ...
Metastasis is an intricate multi-step process that requires the acquisition of several cancer cell features, including the modulation …
Tetraspanin CD9: A Key Regulator of Cell Adhesion in the Immune System.
Reyes R, et al. Front Immunol 2018 - Review. PMID 29760699 Free PMC article.
Through these associations, CD9 influences many cellular activities in the different subtypes of leukocytes and in endothelial cells, including intracellular signaling, proliferation, activation, survival, migration, invasion, adhesion, and diapedesis. ...In this mini-review, however, we will focus particularly on describing and discussing the regulatory effects exerted by CD9 on different adhesion molecules that play pivotal roles in the physiology of leukocytes and endothelial cells, with a particular emphasis in the regulation of adhesion molecules of the integrin and immunoglobulin superfamilies....
Through these associations, CD9 influences many cellular activities in the different subtypes of leukocytes and in endothelial cells, includ …
Getting to the site of inflammation: the leukocyte adhesion cascade updated.
Ley K, et al. Nat Rev Immunol 2007 - Review. PMID 17717539
Neutrophil recruitment, lymphocyte recirculation and monocyte trafficking all require adhesion and transmigration through blood-vessel walls. The traditional three steps of rolling, activation and firm adhesion have recently been augmented and refined. Slow rolling, adhesion strengthening, intraluminal crawling and paracellular and transcellular migration are now recognized as separate, additional steps. ...
Neutrophil recruitment, lymphocyte recirculation and monocyte trafficking all require adhesion and transmigration through blood-vesse …
Kit-independent mast cell adhesion mediated by Notch.
Murata A, et al. Int Immunol 2019. PMID 30299470
Kit/CD117 plays a crucial role in the cell-cell and cell-matrix adhesion of mammalian mast cells (MCs); however, it is unclear whether other adhesion molecule(s) perform important roles in the adhesion of MCs. ...Despite the activation of the same signaling pathways, while Kit supports the adhesion and survival of MCs, Notch only supports adhesion. ...
Kit/CD117 plays a crucial role in the cell-cell and cell-matrix adhesion of mammalian mast cells (MCs); however, …
A model of the effects of cancer cell motility and cellular adhesion properties on tumour-immune dynamics.
Frascoli F, et al. Math Med Biol 2017. PMID 27094601
We consider the effectiveness of the immune response over a range of parameters pertaining to tumour cell motility, cell-to-cell adhesion strength and growth rate. ...In general, the effect of cell-to-cell adhesion on prognosis is dependent on the level of tumour cell motility, with an often unpredictable cross influence between adhesion and motility, which can lead to counterintuitive effects. ...
We consider the effectiveness of the immune response over a range of parameters pertaining to tumour cell motility, cell-to- …
Small hypoxia-primed mesenchymal stem cells attenuate graft-versus-host disease
Kim Y, et al. Leukemia 2018. PMID 29789652 Free PMC article.
Compared with naïve cultured human umbilical cord blood-derived MSCs, SHC-MSCs were resistant to passage-dependent senescence mediated via the monocyte chemoattractant protein-1 and p53/p21 cascade and secreted large amounts of pro-angiogenic and immunomodulatory factors, resulting in suppression of T-cell proliferation. ...Genome-wide DNA methylome and transcriptome analyses indicated that genes related to immune modulation, cell adhesion, and the cell cycle were up-regulated in SHC-MSCs. ...
Compared with naïve cultured human umbilical cord blood-derived MSCs, SHC-MSCs were resistant to passage-dependent senescence mediated via t …
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