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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1952 1
1954 1
1955 1
1956 1
1958 4
1959 3
1960 4
1961 3
1962 2
1963 2
1964 2
1965 1
1973 1
1977 2
1978 2
1980 2
1981 7
1982 15
1983 37
1984 55
1985 83
1986 123
1987 131
1988 207
1989 318
1990 407
1991 598
1992 904
1993 1351
1994 1500
1995 1332
1996 1106
1997 1050
1998 1087
1999 1106
2000 974
2001 962
2002 1032
2003 1051
2004 1120
2005 1099
2006 1160
2007 1145
2008 1128
2009 1104
2010 1097
2011 1339
2012 1376
2013 1333
2014 1333
2015 1283
2016 948
2017 905
2018 798
2019 399
2020 10
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30,819 results
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Page 1
Cell-adhesion molecules and their soluble forms: Promising predictors of "tumor progression" and relapse in leukemia.
Fonseca ICCFE, et al. Tumour Biol 2018 - Review. PMID 30486756
Among these surface markers are proteins involved in cell-cell adhesion or cell-matrix adhesion, and they may play a role in the relapse of leukemia, similar to metastasis in carcinomas. The most important are epithelial cadherin, neural cadherin, epithelial cell-adhesion molecule, and CD44, which can be cleaved and released, and their soluble forms were found increased in serum levels of cancer patients, being implicated, in some cases, with progression, metastases, and relapse. ...
Among these surface markers are proteins involved in cell-cell adhesion or cell-matrix adhesion, and they …
Towards an Understanding of Synapse Formation
Südhof TC. Neuron 2018 - Review. PMID 30359597 Free PMC article.
Synapses are intercellular junctions specialized for fast, point-to-point information transfer from a presynaptic neuron to a postsynaptic cell. ...Synaptic junctions are likely organized by trans-synaptic cell-adhesion molecules (CAMs) that bidirectionally orchestrate synapse formation, restructuring, and elimination. ...
Synapses are intercellular junctions specialized for fast, point-to-point information transfer from a presynaptic neuron to a postsynaptic …
Junctional adhesion molecules mediate transendothelial migration of dendritic cell vaccine in cancer immunotherapy.
Roh SE, et al. Cancer Lett 2018. PMID 30055289
Here, we found that junctional adhesion molecule (JAM)-Like (JAML) is involved in the TEM of mouse bone marrow-derived DCs (BMDCs). ...
Here, we found that junctional adhesion molecule (JAM)-Like (JAML) is involved in the TEM of mouse bone marrow-derived DCs (BMDCs). . …
A human liver cell atlas reveals heterogeneity and epithelial progenitors.
Aizarani N, et al. Nature 2019. PMID 31292543 Free PMC article.
Here we performed single-cell RNA sequencing of about 10,000 cells from normal liver tissue from nine human donors to construct a human liver cell atlas. ...Our human liver cell atlas provides a powerful resource to enable the discovery of previously unknown cell types in normal and diseased livers....
Here we performed single-cell RNA sequencing of about 10,000 cells from normal liver tissue from nine human donors to construct a hum …
Loss of cell adhesion molecule L1 like promotes tumor growth and metastasis in esophageal squamous cell carcinoma.
Tang H, et al. Oncogene 2019. PMID 30622339
In this study, a new tumor suppressor candidate, cell adhesion molecule with homology to L1CAM (CHL1), located at 3p26 which was frequently deleted in ESCC was identified. ...Methylation-specific PCR and FISH assays revealed that down-regulation of CHL1 in both ESCC cell lines and clinical samples were associated with promoter hypermethylation and loss of heterozygosity. ...
In this study, a new tumor suppressor candidate, cell adhesion molecule with homology to L1CAM (CHL1), located at 3p26 which w …
Glucose-6-phosphate dehydrogenase deficiency increases cell adhesion molecules and activates human monocyte-endothelial cell adhesion: Protective role of l-cysteine.
Parsanathan R and Jain SK. Arch Biochem Biophys 2019. PMID 30582899
Endothelial dysfunction is characterized by the loss of nitric oxide (NO) bioavailability, which regulates leukocyte adhesion to endothelium. ...After inhibiting or knocking down G6PD/GSH, the capacity of endothelial cells for monocyte recruitment was assessed by determining the expression of the adhesion molecules intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1), which was upregulated by G6PD deficiency and accompanied by the presence of the oxidative stress markers NADPH oxidase 4 (NOX4), inducible nitric oxide synthase (iNOS), and reactive oxygen species (ROS). ...
Endothelial dysfunction is characterized by the loss of nitric oxide (NO) bioavailability, which regulates leukocyte adhesion to endo …
Healthy attachments: Cell adhesion molecules collectively control myelin integrity.
Li J and Monk KR. J Cell Biol 2019. PMID 31451614 Free PMC article.
Many cell adhesion molecules are present along myelinated axons and in myelinating glia, but functional interactions among these proteins have not been fully elucidated. ...Cell Biol. https://doi.org/10.1083/jcb.201906099) report that distinct adhesion proteins act in coordination to ensure accurate myelination....
Many cell adhesion molecules are present along myelinated axons and in myelinating glia, but functional interactions among the …
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.
Lytle NK, et al. Cell 2019. PMID 30955884 Free PMC article.
In particular, the nuclear hormone receptor retinoic-acid-receptor-related orphan receptor gamma (RORγ), known to drive inflammation and T cell differentiation, was upregulated during pancreatic cancer progression, and its genetic or pharmacologic inhibition led to a striking defect in pancreatic cancer growth and a marked improvement in survival. ...
In particular, the nuclear hormone receptor retinoic-acid-receptor-related orphan receptor gamma (RORγ), known to drive inflammation and T …
Insight into the complex pathophysiology of sickle cell anaemia and possible treatment.
Piccin A, et al. Eur J Haematol 2019 - Review. PMID 30664257
Sickle cell anaemia (SCA) is the consequence of abnormal haemoglobin production due to an inherited point mutation in the β-globin gene. ...Recent studies have also shown that leucocyte adhesion molecules and nitric oxide (NO) depletion are involved in endothelial damage. ...
Sickle cell anaemia (SCA) is the consequence of abnormal haemoglobin production due to an inherited point mutation in the β-globin ge …
Carcinoembryonic Cell Adhesion-Related Molecule 2 Regulates Insulin Secretion and Energy Balance.
Salaheldeen E, et al. Int J Mol Sci 2019 - Review. PMID 31266142 Free PMC article.
The Carcinoembryonic Antigen-Related Cell Adhesion Molecule (CEACAM) family of proteins plays a significant role in regulating peripheral insulin action by participating in the regulation of insulin metabolism and energy balance. ...
The Carcinoembryonic Antigen-Related Cell Adhesion Molecule (CEACAM) family of proteins plays a significant role in regulating …
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