Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1938 1
1945 15
1946 54
1947 82
1948 66
1949 67
1950 123
1951 157
1952 169
1953 184
1954 177
1955 214
1956 197
1957 238
1958 223
1959 251
1960 309
1961 307
1962 322
1963 452
1964 647
1965 545
1966 618
1967 918
1968 1157
1969 1036
1970 1202
1971 1533
1972 1757
1973 1736
1974 1865
1975 1912
1976 1881
1977 1927
1978 2136
1979 2099
1980 2168
1981 2108
1982 2634
1983 2665
1984 2606
1985 2989
1986 3066
1987 3056
1988 3094
1989 3499
1990 3666
1991 3840
1992 3894
1993 4199
1994 4412
1995 4904
1996 4806
1997 5171
1998 5307
1999 5292
2000 5821
2001 6291
2002 7177
2003 7540
2004 8327
2005 9380
2006 9847
2007 10536
2008 11251
2009 12044
2010 13251
2011 14007
2012 14774
2013 15524
2014 15203
2015 15534
2016 15704
2017 15430
2018 14767
2019 5960
2020 86
Text availability
Article attribute
Article type
Publication date

Search Results

303,965 results
Results by year
Filters applied: . Clear all
Page 1
Genome Editing in Induced Pluripotent Stem Cells using CRISPR/Cas9
Ben Jehuda R, et al. Stem Cell Rev Rep 2018 - Review. PMID 29623532
Ever since, fast growing knowledge of different efficient protocols enabled the differentiation of these iPSCs into different cells types utilized for disease modeling. ...By so doing, this technique enables the generation of isogenic controls or isogenic mutated cell lines in order to focus on the pathologies caused by a specific mutation. ...
Ever since, fast growing knowledge of different efficient protocols enabled the differentiation of these iPSCs into different cells t …
Emerging mechanisms of asymmetric stem cell division.
Venkei ZG and Yamashita YM. J Cell Biol 2018 - Review. PMID 30232100 Free PMC article.
The asymmetric cell division of stem cells, which produces one stem cell and one differentiating cell, has emerged as a mechanism to balance stem cell self-renewal and differentiation. ...In this review, we summarize recent progress in understanding the mechanisms and regulations of asymmetric stem cell division....
The asymmetric cell division of stem cells, which produces one stem cell and one differentiating cell, has emerg …
Metabolism in Immune Cell Differentiation and Function.
Chapman NM, et al. Adv Exp Med Biol 2017 - Review. PMID 28875486
There has thus been growing interest in understanding how metabolic processes control immune cell functions under normal and pathophysiological conditions. In this chapter, we summarize how metabolic programs are tuned and what the physiological consequences of metabolic reprogramming are as they relate to immune cell homeostasis, differentiation, and function....
There has thus been growing interest in understanding how metabolic processes control immune cell functions under normal and pathophy …
Single cell transcriptomics of pluripotent stem cells: reprogramming and differentiation.
Natarajan KN, et al. Curr Opin Genet Dev 2017 - Review. PMID 28675884
Single-cell transcriptomics serves as a powerful tool to identify cell states within populations of cells, and to dissect underlying heterogeneity at high resolution. ...Here we review the recent progress and significant findings from application of single-cell technologies on pluripotent stem cells along with a brief outlook on new combinatorial single-cell approaches that further unravel pluripotent stem cell states....
Single-cell transcriptomics serves as a powerful tool to identify cell states within populations of cells, and to dissect unde …
MicroRNA miR-223 as regulator of innate immunity
Yuan X, et al. J Leukoc Biol 2018 - Review. PMID 29969525 Free PMC article.
MiR-223 contributes to myeloid differentiation by enhancing granulopoiesis while inhibiting macrophage differentiation. Uncontrolled myeloid activation has detrimental consequences in inflammatory disease. MiR-223 serves as a negative feedback mechanism controlling excessive innate immune responses in the maintenance of myeloid cell homeostasis. ...
MiR-223 contributes to myeloid differentiation by enhancing granulopoiesis while inhibiting macrophage differentiation. Uncont …
Autophagy in stem cells: repair, remodelling and metabolic reprogramming
Boya P, et al. Development 2018 - Review. PMID 29483129 Free article.
Autophagy serves as a crucial intracellular quality control and repair mechanism but is also involved in cell remodelling during development and cell differentiation. In addition, mitophagy, the process by which damaged mitochondria undergo autophagy, has emerged as key regulator of cell metabolism. ...
Autophagy serves as a crucial intracellular quality control and repair mechanism but is also involved in cell remodelling during deve …
Elucidating the Preadipocyte and Its Role in Adipocyte Formation: a Comprehensive Review
Sarantopoulos CN, et al. Stem Cell Rev Rep 2018 - Review. PMID 29027120
Adipogenesis is a complex process whereby the multipotent adipose-derived stem cell is converted to a preadipocyte before terminal differentiation into the mature adipocyte. Preadipocytes are present throughout adult life, exhibit adipose fat depot specificity, and differentiate and proliferate from distinct progenitor cells. ...
Adipogenesis is a complex process whereby the multipotent adipose-derived stem cell is converted to a preadipocyte before terminal …
Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells
Qi Y, et al. Nat Biotechnol 2017. PMID 28112759 Free PMC article.
Combinatorial application of six pathway inhibitors induces post-mitotic cortical neurons with functional electrophysiological properties by day 16 of differentiation, in the absence of glial cell co-culture. ...Accelerated differentiation into cortical neuron fates should facilitate hPSC-based strategies for disease modeling and cell therapy in CNS disorders....
Combinatorial application of six pathway inhibitors induces post-mitotic cortical neurons with functional electrophysiological properties by …
Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells.
Sotthibundhu A, et al. Stem Cell Res Ther 2016. PMID 27846905 Free PMC article.
IPSCs are sensitive to enzyme dissociation and require a lengthy differentiation time. The shape and size of EBs also play a role in the heterogeneity of end cell products. This research therefore highlights the potential of rapamycin in producing uniform EBs and in shortening iPSC differentiation duration....
IPSCs are sensitive to enzyme dissociation and require a lengthy differentiation time. The shape and size of EBs also play a role in …
Identifying Human Naïve Pluripotent Stem Cells - Evaluating State-Specific Reporter Lines and Cell-Surface Markers.
Collier AJ and Rugg-Gunn PJ. Bioessays 2018 - Review. PMID 29574793
The latest additions to the stem cell hierarchy open up opportunities for understanding human development, reprogramming, and cell state transitions more generally. ...Finally, opportunities and uncertainties in naïve stem cell biology are highlighted, and the current limitations of human naïve pluripotent stem cells considered, particularly in the context of differentiation....
The latest additions to the stem cell hierarchy open up opportunities for understanding human development, reprogramming, and cell
303,965 results
Jump to page
Feedback