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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 2
2000 3
2001 56
2002 234
2003 369
2004 642
2005 775
2006 838
2007 919
2008 933
2009 1066
2010 1352
2011 1502
2012 1569
2013 1601
2014 1563
2015 1593
2016 1580
2017 1622
2018 1569
2019 718
2020 6
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17,578 results
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Page 1
Editorial: Stem Cell Engineering.
Cabral JM and Palecek SP. Biotechnol J 2015. PMID 26447639
This Special issue of Biotechnology Journal explores recent advances in the emerging field of stem cell engineering, with a focus on applying engineering approaches to understanding stem cell biology and enabling translation of stem cells to commercial and clinical products....
This Special issue of Biotechnology Journal explores recent advances in the emerging field of stem cell engineering, with a fo …
Vascular Tissue Engineering: Progress, Challenges, and Clinical Promise.
Song HG, et al. Cell Stem Cell 2018 - Review. PMID 29499152 Free PMC article.
The synergistic combination of emerging advances in tissue fabrication and stem cell engineering promises new strategies for engineering autologous blood vessels that recapitulate not only the mechanical properties of native vessels but also their biological function. ...We also highlight progress in integrating engineered vascular tissues with the host after implantation as well as the exciting pre-clinical and clinical applications of this technology....
The synergistic combination of emerging advances in tissue fabrication and stem cell engineering promises new strategies for …
A Prototype for Modular Cell Engineering.
Wilbanks B, et al. ACS Synth Biol 2018. PMID 29017319
This engineering approach will become increasingly laborious and expensive when seeking to develop desirable strains for optimal production of a large space of biochemicals due to extensive screening. ...We envision that the MODCELL design provides a powerful prototype for modular cell engineering to rapidly create optimal strains for synthesis of a large space of biochemicals....
This engineering approach will become increasingly laborious and expensive when seeking to develop desirable strains for optimal prod …
Engineering cell fitness: lessons for regenerative medicine.
Shakiba N and Zandstra PW. Curr Opin Biotechnol 2017 - Review. PMID 28551499 Free article.
Cell competition results in the loss of weaker cells and the dominance of stronger cells. So-called 'loser' cells are either removed by active elimination or by limiting their access to survival factors. ...Here, we explore the origins and implications of cell competition in development, tissue homeostasis, and in vitro culture. We also provide a forward look on the use of cell competition to interpret multicellular dynamics while offering a perspective on harnessing competition to engineer cells with optimized and controllable fitness characteristics for regenerative medicine applications....
Cell competition results in the loss of weaker cells and the dominance of stronger cells. So-called 'loser' cells are either removed
Platelet-Rich Plasma in Tissue Engineering: Hype and Hope.
Lang S, et al. Eur Surg Res 2018 - Review. PMID 30244245
In this review, we discuss the application of PRP as a cell culture supplement and as part of tissue engineering strategies, particularly emphasizing current hurdles and ambiguities regarding the efficacy of PRP in these approaches. SUMMARY: As a putative autologous replacement for animal-derived supplements such as fetal calf serum (FCS), PRP has been applied as cell culture supplement for the expansion of stem and progenitor cells for tissue engineering applications and cell therapies. ...
In this review, we discuss the application of PRP as a cell culture supplement and as part of tissue engineering strategies, p …
Organoids by design
Takebe T and Wells JM. Science 2019. PMID 31171692
The current challenge is to engineer cellular complexity into organoids in a controlled manner that results in organized assembly and acquisition of tissue function. ...We discuss how the next generation of organoids can be designed by means of an engineering-based narrative design to control patterning, assembly, morphogenesis, growth, and function....
The current challenge is to engineer cellular complexity into organoids in a controlled manner that results in organized assembly and …
Cell and tissue engineering for liver disease.
Bhatia SN, et al. Sci Transl Med 2014 - Review. PMID 25031271 Free PMC article.
Despite the tremendous hurdles presented by the complexity of the liver's structure and function, advances in liver physiology, stem cell biology and reprogramming, and the engineering of tissues and devices are accelerating the development of cell-based therapies for treating liver disease and liver failure. This State of the Art Review discusses both the near- and long-term prospects for such cell-based therapies and the unique challenges for clinical translation....
Despite the tremendous hurdles presented by the complexity of the liver's structure and function, advances in liver physiology, stem cell
Treatment of critical-sized bone defects: clinical and tissue engineering perspectives.
Roddy E, et al. Eur J Orthop Surg Traumatol 2018 - Review. PMID 29080923
Tissue engineering holds promise in the treatment of large bone defects due to advancement of stem cell biology, novel biomaterials, and 3D bioprinting. In this review, we provide an overview of the current operative treatment strategies of critical-sized bone defects as well as the current state of tissue engineering for such defects....
Tissue engineering holds promise in the treatment of large bone defects due to advancement of stem cell biology, novel biomate …
Cell sheet engineering for regenerative medicine: current challenges and strategies.
Owaki T, et al. Biotechnol J 2014 - Review. PMID 24964041
Designed for use in clinical applications, cell sheet engineering has been developed as a unique, scaffold-free method of cell processing utilizing temperature-responsive cell culture vessels. ...However, several challenges stand in the way of the industrialization of cell sheet products and the widespread acceptance of regenerative medicine based on cell sheet engineering. ...
Designed for use in clinical applications, cell sheet engineering has been developed as a unique, scaffold-free method of c
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