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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1967 19
1968 51
1969 69
1970 119
1971 248
1972 360
1973 467
1974 742
1975 748
1976 635
1977 623
1978 525
1979 412
1980 353
1981 360
1982 391
1983 372
1984 409
1985 390
1986 394
1987 339
1988 278
1989 270
1990 301
1991 288
1992 230
1993 218
1994 178
1995 205
1996 176
1997 174
1998 172
1999 231
2000 277
2001 291
2002 261
2003 293
2004 276
2005 271
2006 266
2007 270
2008 282
2009 267
2010 282
2011 251
2012 252
2013 248
2014 226
2015 186
2016 147
2017 190
2018 188
2019 63
2020 1
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15,118 results
Results by year
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Page 1
Regulation of T cell signalling by membrane lipids.
Wu W, et al. Nat Rev Immunol 2016 - Review. PMID 27721483
The plasma membrane is an essential cellular structure that separates the cell interior from the extracellular environment, while allowing for the exchange of signals and materials that are essential for cell survival and function. ...New studies have started to unveil important functions for plasma membrane lipids in regulating T cell signalling. Importantly, it has been shown that the modulation of membrane lipids can be used to harness T cell activity to treat cancer and autoimmunity. ...
The plasma membrane is an essential cellular structure that separates the cell interior from the extracellular environment, wh …
Molecular interactions at the surface of extracellular vesicles
Buzás EI, et al. Semin Immunopathol 2018 - Review. PMID 29663027 Free PMC article.
Some extracellular vesicle surface molecules are shared with those of the plasma membrane of the releasing cell, while other molecules are characteristic for extracellular vesicular surfaces. ...
Some extracellular vesicle surface molecules are shared with those of the plasma membrane of the releasing cell, while other m …
[An update on myasthenia gravis]
Martínez Torre S, et al. Semergen 2018. PMID 29555378 Spanish.
It is currently one of the most understood and characterised autoimmune disorders Its typical symptoms are fluctuating weakness and fatigue that affects a combination of ocular muscles, bulbar functions, as well as limb and respiratory muscles, which are due to an immune attack against the postsynaptic membrane of the neuromuscular junction. ...
It is currently one of the most understood and characterised autoimmune disorders Its typical symptoms are fluctuating weakness and fatigue …
The immunological synapse
Dustin ML. Cancer Immunol Res 2014 - Review. PMID 25367977 Free PMC article.
This Masters' primer will cover the basics of the immunological synapse and some of the applications to tumor immunology....
This Masters' primer will cover the basics of the immunological synapse and some of the applications to tumor immunology....
Plasma Membrane Sheets for Studies of B Cell Antigen Internalization from Immune Synapses.
Nowosad CR and Tolar P. Methods Mol Biol 2017. PMID 28255697
Here we describe a protocol for preparation of plasma membrane sheets (PMSs), which are flexible and fluid membrane substrates that support robust B cell antigen extraction. We show how to attach B cell antigens to the PMSs and how to investigate antigen extraction and endocytosis by fluorescent microscopy and computational image analysis. ...
Here we describe a protocol for preparation of plasma membrane sheets (PMSs), which are flexible and fluid membrane substrates …
Glycocalyx engineering reveals a Siglec-based mechanism for NK cell immunoevasion.
Hudak JE, et al. Nat Chem Biol 2014. PMID 24292068 Free PMC article.
Key to these findings was the use of glycopolymers end-functionalized with phospholipids, which enable the introduction of synthetically defined glycans onto cancer cell surfaces. Remodeling the sialylation status of cancer cells affected the susceptibility to NK cell cytotoxicity via Siglec-7 engagement in a variety of tumor types. ...
Key to these findings was the use of glycopolymers end-functionalized with phospholipids, which enable the introduction of synthetically def …
Plasma membrane segregation during T cell activation: probing the order of domains.
Harder T, et al. Curr Opin Immunol 2007 - Review. PMID 17628460
T cell activation leads to a segregation of plasma membrane domains to form TCR signalling clusters and eventually immunological synapses. At these T cell activation sites signalling protein networks reside in plasma membrane regions which adopt a highly ordered physical state. ...
T cell activation leads to a segregation of plasma membrane domains to form TCR signalling clusters and eventually immunologic …
RNA Therapeutics for Tissue Engineering
Balmayor ER and Evans CH. Tissue Eng Part A 2019. PMID 30426843
Not only is it unstable and difficult to deliver across hydrophobic cell membranes, but extraneous RNA also activates innate immune nucleic acid sensors, which makes it toxic and inflammatory....
Not only is it unstable and difficult to deliver across hydrophobic cell membranes, but extraneous RNA also activates innate immune n …
Connexins and their channels in inflammation
Willebrords J, et al. Crit Rev Biochem Mol Biol 2016 - Review. PMID 27387655 Free PMC article.
The purpose of inflammation is to eliminate the initial cell injury trigger, to clear out dead cells from damaged tissue and to initiate tissue regeneration. ...
The purpose of inflammation is to eliminate the initial cell injury trigger, to clear out dead cells from damaged tissue and to initi …
15,118 results
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