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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1956 2
1957 3
1958 1
1959 1
1961 1
1964 5
1965 45
1966 96
1967 169
1968 283
1969 397
1970 455
1971 761
1972 987
1973 1147
1974 1639
1975 1622
1976 1779
1977 1781
1978 1819
1979 2307
1980 2542
1981 2482
1982 2705
1983 2660
1984 2835
1985 2794
1986 2895
1987 2818
1988 2984
1989 3337
1990 3690
1991 3416
1992 3554
1993 3759
1994 3700
1995 3503
1996 3373
1997 3320
1998 3442
1999 3780
2000 4748
2001 5197
2002 5508
2003 5817
2004 5947
2005 5869
2006 6023
2007 6046
2008 6447
2009 6076
2010 6487
2011 6836
2012 7054
2013 6883
2014 6417
2015 6141
2016 6131
2017 5888
2018 5275
2019 2295
2020 40
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184,112 results
Results by year
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Page 1
The plasma membrane as a capacitor for energy and metabolism.
Ray S, et al. Am J Physiol Cell Physiol 2016 - Review. PMID 26771520 Free PMC article.
Few people will suggest that the membrane is the most critical element of a cell in terms of function and physiology. Those that consider the membrane critical will point to its obvious barrier function regulated by the lipid bilayer and numerous ion channels that regulate homeostatic gradients. ...Within this framework, the membrane then is the primary and critical regulator of stress and disease adaptation of the cell....
Few people will suggest that the membrane is the most critical element of a cell in terms of function and physiology. Those th …
The mystery of membrane organization: composition, regulation and roles of lipid rafts.
Sezgin E, et al. Nat Rev Mol Cell Biol 2017 - Review. PMID 28356571 Free PMC article.
Cellular plasma membranes are laterally heterogeneous, featuring a variety of distinct subcompartments that differ in their biophysical properties and composition. ...The membrane raft hypothesis formalized a physicochemical principle for a subtype of such lateral membrane heterogeneity, in which the preferential associations between cholesterol and saturated lipids drive the formation of relatively packed (or ordered) membrane domains that selectively recruit certain lipids and proteins. ...
Cellular plasma membranes are laterally heterogeneous, featuring a variety of distinct subcompartments that differ in their biophysic …
Tensile Forces and Mechanotransduction at Cell-Cell Junctions.
Charras G and Yap AS. Curr Biol 2018 - Review. PMID 29689229 Free article.
Cell-cell junctions are specializations of the plasma membrane responsible for physically integrating cells into tissues. We are now beginning to appreciate the diverse impacts that mechanical forces exert upon the integrity and function of these junctions. Currently, this is best understood for cadherin-based adherens junctions in epithelia and endothelia, where cell-cell adhesion couples the contractile cytoskeletons of cells together to generate tissue-scale tension. ...
Cell-cell junctions are specializations of the plasma membrane responsible for physically integrating cells into tissue
Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and cell signaling.
Head BP, et al. Biochim Biophys Acta 2014 - Review. PMID 23899502 Free PMC article.
The plasma membrane in eukaryotic cells contains microdomains that are enriched in certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form membrane/lipid rafts (MLR). ...This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. ...
The plasma membrane in eukaryotic cells contains microdomains that are enriched in certain glycosphingolipids, gangliosides, and ster …
Selective effect of cell membrane on synaptic neurotransmission.
Postila PA, et al. Sci Rep 2016. PMID 26782980 Free PMC article.
The results provide compelling evidence that NTs are divided into membrane-binding and membrane-nonbinding molecules. NTs adhere to the postsynaptic membrane surface whenever the ligand-binding sites of their synaptic receptors are buried in the lipid bilayer. ...The revised paradigm, highlighting the importance of cell membrane and specific lipids for neurotransmission, should to be of interest to neuroscientists, drug industry and the general public alike....
The results provide compelling evidence that NTs are divided into membrane-binding and membrane-nonbinding molecules. NTs adhe …
Interplay between tight junctions & adherens junctions
Campbell HK, et al. Exp Cell Res 2017 - Review. PMID 28372972 Free PMC article.
Cell-cell adhesions are critical for the development and maintenance of tissues. Present at sites of cell-cell contact are the adherens junctions and tight junctions. The adherens junctions mediate cell-cell adhesion via the actions of nectins and cadherins. The tight junctions regulate passage of ions and small molecules between cells and establish cell polarity. ...
Cell-cell adhesions are critical for the development and maintenance of tissues. Present at sites of cell-cell c
Tuning B cell responses to antigens by cell polarity and membrane trafficking.
Del Valle Batalla F, et al. Mol Immunol 2018 - Review. PMID 29935436
Such antigens elicit the formation of an immune synapse (IS), where local cytoskeleton rearrangements coupled to mechanical forces and membrane trafficking orchestrate the extraction and processing of antigens in B cells. In this review, we discuss the molecular mechanisms that regulate polarized membrane trafficking and mechanical properties of the immune synapse, as well as the potential extracellular cues from the environment, which may impact the ability of B cells to sense and acquire antigens at the immune synapse. ...
Such antigens elicit the formation of an immune synapse (IS), where local cytoskeleton rearrangements coupled to mechanical forces and me
Phosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.
Marat AL and Haucke V. EMBO J 2016 - Review. PMID 26888746 Free PMC article.
Phosphoinositides (PIs) form a minor class of phospholipids with crucial functions in cell physiology, ranging from cell signalling and motility to a role as signposts of compartmental membrane identity. Phosphatidylinositol 3-phosphates are present at the plasma membrane and within the endolysosomal system, where they serve as key regulators of both cell signalling and of intracellular membrane traffic. ...
Phosphoinositides (PIs) form a minor class of phospholipids with crucial functions in cell physiology, ranging from cell signa …
The Lipid Droplet and the Endoplasmic Reticulum
Ohsaki Y, et al. Adv Exp Med Biol 2017 - Review. PMID 28815525
The ER-LD association may appear morphologically similar to the prototypical membrane contact sites found between the ER and other organelles, but the functional relationship between the ER and LDs is unique in that highly hydrophobic lipid esters are transported between them. ...More recently, LDs in the nucleus were found to be closely adhered to the inner nuclear membrane, representing a specialized form of the ER-LD association. ...
The ER-LD association may appear morphologically similar to the prototypical membrane contact sites found between the ER and other or …
Editorial note
Peixoto PM, et al. J Bioenerg Biomembr 2017. PMID 27714488
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