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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1967 2
1968 4
1970 17
1971 65
1972 124
1973 166
1974 223
1975 248
1976 276
1977 369
1978 374
1979 446
1980 422
1981 449
1982 589
1983 658
1984 856
1985 766
1986 919
1987 874
1988 991
1989 1125
1990 1283
1991 1174
1992 960
1993 1058
1994 1049
1995 1047
1996 1063
1997 1144
1998 1253
1999 1379
2000 1702
2001 1783
2002 1874
2003 1992
2004 2273
2005 2737
2006 3302
2007 3804
2008 3918
2009 4273
2010 5011
2011 5777
2012 6935
2013 7862
2014 7882
2015 8123
2016 8531
2017 8447
2018 8352
2019 5078
2020 129
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107,840 results
Results by year
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Page 1
Cell Proliferation and Cytotoxicity Assays.
Adan A, et al. Curr Pharm Biotechnol 2016 - Review. PMID 27604355
Cell viability is defined as the number of healthy cells in a sample and proliferation of cells is a vital indicator for understanding the mechanisms in action of certain genes, proteins and pathways involved cell survival or death after exposing to toxic agents. Generally, methods used to determine viability are also common for the detection of cell proliferation. Cell cytotoxicity and proliferation assays are generally used for drug screening to detect whether the test molecules have effects on cell proliferation or display direct cytotoxic effects. ...
Cell viability is defined as the number of healthy cells in a sample and proliferation of cells is a vital indicator for understandin
Tocotrienols Modulate a Life or Death Decision in Cancers
Tham SY, et al. Int J Mol Sci 2019 - Review. PMID 30654580 Free PMC article.
Resistance toward cell death and enhancement of cell survival are the common adaptations in cancer due to its infinite proliferative capacity. ...The cell death mechanisms elicited by tocotrienols, particularly apoptosis and autophagy, are highlighted. The influences of several cell survival signaling pathways in shaping cancer cell death, particularly NF-κB, PI3K/Akt, MAPK, and Wnt, are also reviewed. ...
Resistance toward cell death and enhancement of cell survival are the common adaptations in cancer due to its infinite …
Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets.
Duan Q, et al. Bioinformatics 2014. PMID 25100688 Free PMC article.
Here we introduce Drug/Cell-line Browser (DCB), an online interactive HTML5 data visualization tool for interacting with three of the recently published datasets of cancer cell lines/drug-viability studies. ...DCB can help in understanding drug response patterns and prioritizing drug/cancer cell line interactions by tissue of origin or cancer subtype. ...
Here we introduce Drug/Cell-line Browser (DCB), an online interactive HTML5 data visualization tool for interacting with three …
The Effects of Adjuvant Fermented Wheat Germ Extract on Cancer Cell Lines: A Systematic Review.
Zhurakivska K, et al. Nutrients 2018. PMID 30347664 Free PMC article.
Various types of cancer cells treated with FWGE have been analyzed, showing mainly cytotoxic effects, alteration of the cell cycle, antiproliferative effects, and induction of apoptosis. FWGE can be a promising drug component in cancer treatment; however, further in vitro and in vivo studies are necessary to prove its effectiveness and safety in humans....
Various types of cancer cells treated with FWGE have been analyzed, showing mainly cytotoxic effects, alteration of the cell c …
The effects of autophagy on vascular endothelial cells induced by airborne PM2.5.
Zhou Z, et al. J Environ Sci (China) 2018. PMID 29628085
A Cell Counting Kit 8 (CCK8) assay demonstrated that PM2.5 exposure decreased the proliferation of HUVECs in a dose-dependent manner. ...Furthermore, promoting autophagy in PM2.5-exposed HUVECs with rapamycin increased the cell survival rate, whereas inhibiting autophagy via 3-methyladenine significantly decreased cell survival. ...
A Cell Counting Kit 8 (CCK8) assay demonstrated that PM2.5 exposure decreased the proliferation of HUVECs in a dose-dependent manner. …
Pharmacodynamic models of age-structured cell populations.
Krzyzanski W. J Pharmacokinet Pharmacodyn 2015 - Review. PMID 26377617
The purpose of this work is to review basic pharmacodynamic (PD) models describing drug effects on cell populations and expand them to age-structured models using the theory of physiologically structured populations. ...As an example of more complex cell population, the age distribution of human red blood cells has been simulated based on a recent model of red blood cell survival. ...
The purpose of this work is to review basic pharmacodynamic (PD) models describing drug effects on cell populations and …
Effects of polyunsaturated fatty acids and of their oxidation products on cell survival.
Bégin ME. Chem Phys Lipids 1987 - Review. PMID 3319230
The stimulatory, cytostatic and cytotoxic effects of polyunsaturated fatty acids, prostaglandins, thromboxanes, hydroperoxy fatty acids, hydroxy fatty acids and leukotrienes on normal and tumor cells are described. Their effects are related to the ability of the cells to undergo lipid peroxidation. The significance of controlled peroxidation of selected polyunsaturated fatty acids in the control of tumor development is examined. ...
The stimulatory, cytostatic and cytotoxic effects of polyunsaturated fatty acids, prostaglandins, thromboxanes, hydroperoxy fatty aci …
A Systematic Review of Iran's Medicinal Plants With Anticancer Effects.
Asadi-Samani M, et al. J Evid Based Complementary Altern Med 2016 - Review. PMID 26297173
This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines. Thirty-six medicinal plants alongside their products with anticancer effects as well as the most important plant compounds responsible for the plants' anticancer effect were introduced. Phenolic and alkaloid compounds were demonstrated to have anticancer effects on various cancers in most studies. The plants and their active compounds exerted anticancer effects by removing free radicals and antioxidant effects, cell cycle arrest, induction of apoptosis, and inhibition of angiogenesis. ...
This study is a review of medicinal plants in Iran with already investigated anticancer effects on various cell lines. Thirty- …
Estrogen matters in metastasis
Nair S and Sachdeva G. Steroids 2018 - Review. PMID 30031855
This is followed by their intravasation, extravasation, survival, proliferation, and colonization into distant organs. Unlike well-confined tumors, which respond favorably to anti-cancer therapeutics, metastatic tumors are life-threatening and incurable. ...
This is followed by their intravasation, extravasation, survival, proliferation, and colonization into distant organs. Unlike well-co …
Acrylamide-derived cytotoxic, anti-proliferative, and apoptotic effects on A549 cells.
Kacar S, et al. Hum Exp Toxicol 2018. PMID 28569085
It has been studied in a wealth of cell lines on which it proved to have various toxic effects. Among these cell lines, human lung adenocarcinoma cell line (A549) is one of that on which acrylamide's toxicity has not been studied well yet. ...CONCLUSION: Our research suggests that acrylamide causes cytotoxic, anti-proliferative, and apoptotic effects on A549 cells at 4.6 mM IC(50) dose in 24 h....
It has been studied in a wealth of cell lines on which it proved to have various toxic effects. Among these cell lines, …
107,840 results
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