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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 8
1967 14
1968 58
1969 108
1970 101
1971 131
1972 143
1973 145
1974 178
1975 162
1976 133
1977 137
1978 142
1979 149
1980 149
1981 161
1982 175
1983 210
1984 216
1985 227
1986 240
1987 255
1988 272
1989 251
1990 237
1991 246
1992 273
1993 319
1994 266
1995 321
1996 236
1997 247
1998 310
1999 308
2000 362
2001 419
2002 465
2003 377
2004 382
2005 447
2006 534
2007 567
2008 638
2009 620
2010 632
2011 626
2012 677
2013 754
2014 705
2015 708
2016 726
2017 696
2018 656
2019 250
2020 5
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16,488 results
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Page 1
[Lymphatic system in central nervous system].
Thomas JL, et al. Med Sci (Paris) 2019 - Review. PMID 30672459 French. Free article.
The considerable metabolic activity of the central nervous system (CNS) requires an efficient system of tissue drainage and detoxification. ...This system is coupling a cerebral "glymphatic" flow with a meningeal lymphatic vasculature. The "glymphatic" system includes perivascular spaces and astrocytes, and drains interstitial fluids, from and towards the CSF. ...
The considerable metabolic activity of the central nervous system (CNS) requires an efficient system of tissue d …
Myeloid Cells in the Central Nervous System.
Herz J, et al. Immunity 2017 - Review. PMID 28636961 Free PMC article.
The central nervous system (CNS) and its meningeal coverings accommodate a diverse myeloid compartment that includes parenchymal microglia and perivascular macrophages, as well as choroid plexus and meningeal macrophages, dendritic cells, and granulocytes. ...
The central nervous system (CNS) and its meningeal coverings accommodate a diverse myeloid compartment that includes pa …
Multifaceted interactions between adaptive immunity and the central nervous system.
Kipnis J. Science 2016 - Review. PMID 27540163 Free PMC article.
Neuroimmunologists seek to understand the interactions between the central nervous system (CNS) and the immune system, both under homeostatic conditions and in diseases. ...
Neuroimmunologists seek to understand the interactions between the central nervous system (CNS) and the immune syste
Reactive Astrocytes: Production, Function, and Therapeutic Potential
Liddelow SA and Barres BA. Immunity 2017 - Review. PMID 28636962 Free article.
Astrocytes constitute approximately 30% of the cells in the mammalian central nervous system (CNS). They are integral to brain and spinal-cord physiology and perform many functions important for normal neuronal development, synapse formation, and proper propagation of action potentials. ...
Astrocytes constitute approximately 30% of the cells in the mammalian central nervous system (CNS). They are integral t …
Infectious immunity in the central nervous system and brain function.
Klein RS, et al. Nat Immunol 2017 - Review. PMID 28092376 Free PMC article.
Although acute alterations in mental status due to inflammation are a hallmark of central nervous system (CNS) infections with neurotropic pathogens, post-infectious neurologic dysfunction has traditionally been attributed to irreversible damage caused by the pathogens themselves. ...
Although acute alterations in mental status due to inflammation are a hallmark of central nervous system (CNS) infectio …
Protective and Pathological Immunity during Central Nervous System Infections.
Klein RS and Hunter CA. Immunity 2017 - Review. PMID 28636958 Free PMC article.
The concept of immune privilege of the central nervous system (CNS) has dominated the study of inflammatory processes in the brain. ...Advances in these areas have broadened our comprehension of how the immune system functions in the brain and can readily overcome immune privilege....
The concept of immune privilege of the central nervous system (CNS) has dominated the study of inflammatory processes i …
Central Nervous System: (Immunological) Ivory Tower or Not?
Marin IA and Kipnis J. Neuropsychopharmacology 2017 - Review. PMID 27402496 Free PMC article.
The view of the nervous system being the victim of destructive inflammation during autoimmunity, degeneration, or injury has been rapidly changing. Recent studies are supporting the idea that the immune system provides support for the nervous system at various levels. Though cell patrolling through the nervous system parenchyma is limited compared with other tissues, immune cell presence within the central nervous system (CNS; microglia), as well as around it (in the meningeal spaces and choroid plexus) has been shown to be important for brain tissue maintenance and function. ...
The view of the nervous system being the victim of destructive inflammation during autoimmunity, degeneration, or injury has b …
Advances in Meningeal Immunity
Rua R and McGavern DB. Trends Mol Med 2018 - Review. PMID 29731353 Free PMC article.
The central nervous system (CNS) is an immunologically specialized tissue protected by a blood-brain barrier. The CNS parenchyma is enveloped by a series of overlapping membranes that are collectively referred to as the meninges. ...
The central nervous system (CNS) is an immunologically specialized tissue protected by a blood-brain barrier. The CNS p …
The movers and shapers in immune privilege of the CNS
Engelhardt B, et al. Nat Immunol 2017 - Review. PMID 28092374
Discoveries leading to an improved understanding of immune surveillance of the central nervous system (CNS) have repeatedly provoked dismissal of the existence of immune privilege of the CNS. ...There is a unique system of lymphatic drainage from the CNS to the peripheral lymph nodes. We summarize current knowledge on the cellular and molecular mechanisms involved in immune-cell trafficking and lymphatic drainage from the CNS, and we take into account differences in rodent and human CNS anatomy....
Discoveries leading to an improved understanding of immune surveillance of the central nervous system (CNS) have repeat …
16,488 results
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