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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1952 1
1963 1
1964 2
1965 14
1966 23
1967 14
1968 23
1969 25
1970 28
1971 26
1972 18
1973 50
1974 28
1975 28
1976 21
1977 26
1978 30
1979 22
1980 11
1981 15
1982 5
1983 12
1984 11
1985 18
1986 20
1987 20
1988 15
1989 16
1990 16
1991 5
1992 14
1993 14
1994 8
1995 11
1996 12
1997 15
1998 19
1999 17
2000 23
2001 27
2002 34
2003 37
2004 19
2005 28
2006 25
2007 41
2008 32
2009 49
2010 55
2011 62
2012 73
2013 84
2014 73
2015 80
2016 93
2017 89
2018 80
2019 51
2020 0
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1,572 results
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Page 1
Drug-Induced Liver Injury.
Fisher K, et al. Arch Pathol Lab Med 2015 - Review. PMID 26125428
CONTEXT: Drug-induced liver injury (DILI) represents a diverse set of responses following exposure to any manufactured or naturally occurring chemical compound. ...CONCLUSIONS: Drug-induced liver injury due to prescription, over-the-counter, and herbal products is a major cause of liver disease in the United States and around the world. ...
CONTEXT: Drug-induced liver injury (DILI) represents a diverse set of responses following exposure to any manufa …
Drug-Induced Liver Injury.
Almario EE, et al. Biomed Res Int 2017. PMID 28164116 Free PMC article.
Recent Advances in the Histopathology of Drug-Induced Liver Injury.
Kleiner DE. Surg Pathol Clin 2018 - Review. PMID 29751876 Free PMC article.
Drug-induced liver injury (DILI) is constantly changing as new drugs are approved and as new herbals and dietary supplements (HDS) reach the market. ...Recent reports of iatrogenic liver injury are reviewed with attention to immunomodulatory and antineoplastic agents as well as reports of injury associated with HDS use....
Drug-induced liver injury (DILI) is constantly changing as new drugs are approved and as new herbals and dietary
Drug-induced Liver Injury: The Hepatic Pathologist's Approach.
Kleiner DE. Gastroenterol Clin North Am 2017 - Review. PMID 28506365 Free PMC article.
The evaluation of liver biopsies in suspected drug-induced liver injury (DILI) can be complex. The biopsy may be approached systematically, by identification of histologic lesions and then identification of the overall pattern of injury. Potential DILI must be separated from concomitant non-DILI liver disease. The findings can be analyzed with respect to the various prescription and nonprescription medications and dietary supplements under suspicion to provide a complete interpretation of the findings. ...
The evaluation of liver biopsies in suspected drug-induced liver injury (DILI) can be complex. The biopsy …
Cell death in drug-induced liver injury.
Iorga A and Dara L. Adv Pharmacol 2019 - Review. PMID 31307591
Drug-induced liver injury (DILI) is an important cause of liver toxicity which can have varying clinical presentations, the most severe of which being acute liver failure. ...IDILI is an unpredictable form of liver injury that is not dose dependent, occurs in individuals with a genetic predisposition, and presents with variable latency. ...
Drug-induced liver injury (DILI) is an important cause of liver toxicity which can have varying clinical
Animal models of drug-induced liver injury.
McGill MR and Jaeschke H. Biochim Biophys Acta Mol Basis Dis 2019 - Review. PMID 31007174 Free PMC article.
Drug-induced liver injury (DILI) presents unique challenges for consumers, clinicians, and regulators. It is the most common cause of acute liver failure in the US. ...
Drug-induced liver injury (DILI) presents unique challenges for consumers, clinicians, and regulators. It is the
Drug rechallenge following drug-induced liver injury.
Hunt CM, et al. Hepatology 2017 - Review. PMID 28295448
Nearly 50 drugs are associated with positive rechallenge after drug-induced liver injury (DILI): antimicrobials; and central nervous system, cardiovascular and oncology therapeutics. ...Drug rechallenge following drug-induced liver injury is associated with up to 13% mortality in prospective series of all prescribed drugs. ...
Nearly 50 drugs are associated with positive rechallenge after drug-induced liver injury (DILI): antimicrobials; …
Phenotypes and Pathology of Drug-Induced Liver Disease.
Goodman ZD. Clin Liver Dis 2017 - Review. PMID 27842777
Drug hepatotoxicity can simulate nearly any clinical syndrome or pathologic lesion that may occur in the liver, so clinical and histopathologic diagnosis of drug-induced liver injury may be difficult. ...Recognition of these patterns or phenotypes in liver biopsy material is helpful in evaluation of clinical cases of suspected drug-induced liver injury....
Drug hepatotoxicity can simulate nearly any clinical syndrome or pathologic lesion that may occur in the liver, so clinical an
A proposed pathologic sub-classification of drug-induced liver injury.
Wang T, et al. Hepatol Int 2019 - Clinical Trial. PMID 30977034
BACKGROUND: The aim of this study was to establish a new pathologic sub-classification of drug-induced liver injury (DILI) in combination with serum chemistry parameters and clinical observations. ...Greater attention should be paid to drug-induced bile duct vanishing syndrome and drug-induced vascular injury. CONCLUSION: The pathological classification is simple to adopt and practically useful, which demonstrates the consistency between clinical features and liver pathology. ...
BACKGROUND: The aim of this study was to establish a new pathologic sub-classification of drug-induced liver injury
Histopathological challenges in suspected drug-induced liver injury.
Kleiner DE. Liver Int 2018 - Review. PMID 28865179
When a patient with suspected drug-induced liver injury (DILI) undergoes liver biopsy, the pathologist is confronted with two major challenges. The first and most important is to establish the pattern(s) of injury which are present. Patterns of injury represent stereotypical responses of an organ to injury and relate to specific aetiologies of liver damage. ...
When a patient with suspected drug-induced liver injury (DILI) undergoes liver biopsy, the pathologist is …
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