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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 3
1998 5
1999 8
2000 7
2001 28
2002 33
2003 34
2004 45
2005 39
2006 36
2007 36
2008 55
2009 39
2010 45
2011 48
2012 38
2013 42
2014 63
2015 55
2016 44
2017 48
2018 45
2019 18
2020 0
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711 results
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Page 1
CCR4 and its ligands: from bench to bedside
Yoshie O and Matsushima K. Int Immunol 2015 - Review. PMID 25087232
All the known chemokine receptors are seven transmembrane-type receptors. Humans have 18 chemotactic and 5 atypical non-chemotactic (recycling or scavenging) receptors. CC chemokine receptor 4 (CCR4) is the receptor for two CC chemokine ligands (CCLs)-CCL17 (also called thymus- and activation-regulated chemokine) and CCL22 (macrophage-derived chemokine). ...
All the known chemokine receptors are seven transmembrane-type receptors. Humans have 18 chemotactic and 5 atypical non-chemotactic ( …
Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease.
Ruland C, et al. Brain Behav Immun 2017. PMID 28642092
The CC chemokine ligand 17 (CCL17) and its cognate CC chemokine receptor 4 (CCR4) are known to control leukocyte migration, maintenance of T(H)17 cells, and regulatory T cell (T(reg)) expansion in vivo. ...
The CC chemokine ligand 17 (CCL17) and its cognate CC chemokine receptor 4 (CCR4) are known to control leukocyte migration, ma …
Serum chemokine CCL17/thymus activation and regulated chemokine is correlated with coronary artery diseases.
Ye Y, et al. Atherosclerosis 2015. PMID 25555269
OBJECTIVE: It was recently reported that chemokine CC-motif ligand 17 (CCL17)-expressing dendritic cells drove atherosclerosis by restraining regulatory T cell homeostasis in an animal model. ...
OBJECTIVE: It was recently reported that chemokine CC-motif ligand 17 (CCL17)-expressing dendritic cells drove atherosclerosis by res …
Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms
Watanabe H. J Immunol Res 2018 - Review. PMID 29744372 Free PMC article.
In this review, we will emphasize that elevations in the levels of several cytokines/chemokines, including tumor necrosis factor- (TNF-) α and the thymus and activation-regulated chemokine (TARC/CCL17), during the early stage of disease, are good markers allowing the early recognition of HHV-6 reactivation. ...
In this review, we will emphasize that elevations in the levels of several cytokines/chemokines, including tumor necrosis factor- (TNF-) α a …
CCL17 exerts a neuroimmune modulatory function and is expressed in hippocampal neurons
Fülle L, et al. Glia 2018. PMID 30277599
Using a fluorescence reporter mouse model, we demonstrate that the chemokine CCL17, a ligand of the chemokine receptor CCR4, is produced in the murine brain, particularly in a subset of hippocampal CA1 neurons. ...Taken together, our data identify CCL17 as a homeostatic and inducible neuromodulatory chemokine affecting the presence and morphology of microglia and synaptic transmission in the hippocampus....
Using a fluorescence reporter mouse model, we demonstrate that the chemokine CCL17, a ligand of the chemokine receptor CCR4, i …
The C-C Chemokines CCL17 and CCL22 and Their Receptor CCR4 in CNS Autoimmunity
Scheu S, et al. Int J Mol Sci 2017 - Review. PMID 29099057 Free PMC article.
Chemokine ligand-receptor interactions orchestrate leukocyte trafficking and influence multiple pathophysiological cellular processes, including antigen presentation and cytokine production by dendritic cells (DCs). The C-C class chemokines 17 (CCL17) and 22 (CCL22) and their C-C chemokine receptor 4 (CCR4) have been shown to play an important role in homeostasis and inflammatory responses. ...
Chemokine ligand-receptor interactions orchestrate leukocyte trafficking and influence multiple pathophysiological cellular processes
Tumor-associated macrophage or chemokine ligand CCL17 positively regulates the tumorigenesis of hepatocellular carcinoma.
Zhu F, et al. Med Oncol 2016. PMID 26781124
Alternatively activated macrophages (M2) can secrete chemokines, such as chemokine ligand 17 (CCL17), and are associated with promoting tumorigenesis of hepatocellular carcinoma (HCC). ...
Alternatively activated macrophages (M2) can secrete chemokines, such as chemokine ligand 17 (CCL17), and are associated with promoti …
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