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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 2
1951 3
1952 1
1953 2
1954 2
1955 1
1957 1
1959 1
1961 1
1962 1
1990 1
1992 2
1993 2
1994 17
1995 56
1996 185
1997 280
1998 323
1999 415
2000 440
2001 498
2002 442
2003 470
2004 479
2005 534
2006 586
2007 568
2008 596
2009 643
2010 604
2011 601
2012 608
2013 600
2014 656
2015 598
2016 572
2017 504
2018 457
2019 167
2020 6
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10,728 results
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Page 1
Novel lymphocyte-specific CC chemokines and their receptors.
Yoshie O, et al. J Leukoc Biol 1997 - Review. PMID 9365118
Using these sequences, we have cloned five novel human CC chemokines termed TARC, LARC, ELC, SLC, and PARC. These chemokines are constitutively expressed especially in some lymphoid tissues with individually unique expression patterns. ...Collectively, these five CC chemokines may constitute a new category of CC chemokines that are involved in trafficking and homing of particular subsets of lymphocytes in particular lymphoid tissue microenvironments....
Using these sequences, we have cloned five novel human CC chemokines termed TARC, LARC, ELC, SLC, and PARC. These chemokines a …
An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium
Rump L, et al. Cytokine 2017. PMID 28648867 Free PMC article.
However, as little information is available on which chemokines are expressed/presented by the ECs themselves, the purpose of the study was to ascertain which of the CC chemokines were localised in RA ECs. ...Of the 26 chemokines studied, 19 have not been previously observed in RA ECs. Four of these novel chemokines, namely CCL7, CCL14, CCL16 and CCL22 were present on ≥60% of vessels. ...
However, as little information is available on which chemokines are expressed/presented by the ECs themselves, the purpose of the stu …
Atlantic cod (Gadus morhua) CC chemokines: Diversity and expression analysis.
Borza T, et al. Dev Comp Immunol 2010. PMID 20381521
Chemokines are a large, diverse group of small cytokines that can be classified into several families, including the CC chemokines that are characterized by two adjacent cysteines near their amino terminus. CC chemokines play a pivotal role in host defense mechanisms by inducing leukocyte chemotaxis under physiological and inflammatory conditions. ...
Chemokines are a large, diverse group of small cytokines that can be classified into several families, including the CC chemokines
Hemofiltrate CC chemokines with unique biochemical properties: HCC-1/CCL14a and HCC-2/CCL15.
Forssmann U, et al. J Leukoc Biol 2001 - Review. PMID 11527984
The extremely high concentration of CCL14a in human plasma is exceptional for chemokines and led to the identification of this chemokine. ...Hemofiltrate CC chemokines are chemoattractants for different types of leukocytes including monocytes, eosinophils, T cells, dendritic cells, and neutrophils. ...
The extremely high concentration of CCL14a in human plasma is exceptional for chemokines and led to the identification of this chemok …
CXC and CC chemokines form mixed heterodimers: association free energies from molecular dynamics simulations and experimental correlations.
Nesmelova IV, et al. J Biol Chem 2008. PMID 18550532 Free PMC article.
CXC and CC chemokines are involved in numerous biological processes, and their function in situ may be significantly influenced by heterodimer formation, as was recently reported, for example, for CXC chemokines CXCL4/PF4 and CXCL8/IL8 that interact to form heterodimers that modulate chemotactic and cell proliferation activities. ...Even though structural homology among monomer folds of all CXC and CC chemokines permits heterodimer assembly, our calculated association free energies depend upon the particular pair of chemokines in terms of the net electrostatic and nonelectrostatic forces involved, as well as (for CC/CXC mixed chemokines) the selection of dimer type (CC or CXC). ...
CXC and CC chemokines are involved in numerous biological processes, and their function in situ may be significantly influenced by he …
CC family chemokines directly regulate myoblast responses to skeletal muscle injury.
Yahiaoui L, et al. J Physiol 2008. PMID 18566004 Free PMC article.
Chemokines have been implicated in the promotion of leucocyte trafficking to diseased muscle. The purpose of this study was to determine whether a subset of inflammatory chemokines are able to directly drive myoblast proliferation, an essential early component of muscle regeneration, in a manner which is entirely independent of leucocytes. ...Within an in vitro myogenic wound healing assay devoid of leucocytes, all chemokines significantly accelerated the time course of myoblast wound closure after mechanical injury. ...
Chemokines have been implicated in the promotion of leucocyte trafficking to diseased muscle. The purpose of this study was to determ
Gene expression of CC chemokines in experimental acute tubulointerstitial nephritis.
Ou ZL, et al. J Lab Clin Med 1999. PMID 10385480
CC chemokines, mostly chemoattractants for mononuclear leukocytes, are molecules that are potentially responsible for the recruitment of these cells in the kidney. ...These results suggest that multiple CC chemokines may play a role in the recruitment of leukocytes in this model and that the expression pattern of CC chemokines depends on the type of kidney injury....
CC chemokines, mostly chemoattractants for mononuclear leukocytes, are molecules that are potentially responsible for the recruitment …
CCL27/CCL28-CCR10 Chemokine Signaling Mediates Migration of Lymphatic Endothelial Cells
Karnezis T, et al. Cancer Res 2019. PMID 30709930
While chemokines are known to provide directional navigation for migrating immune cells, their role in mediating LEC migration during tumor-associated lymphangiogenesis is not well defined. ...In vivo analyses showed that LECs are recruited to a CCL27 or CCL28 source, while VEGFD was required in combination with these chemokines to enable formation of coherent lymphatic vessels. ...
While chemokines are known to provide directional navigation for migrating immune cells, their role in mediating LEC migration during …
Silent chemoattractant receptors: D6 as a decoy and scavenger receptor for inflammatory CC chemokines.
Locati M, et al. Cytokine Growth Factor Rev 2005 - Review. PMID 15996892
D6 binds most inflammatory, but not homeostatic, CC chemokines and shuttles in a ligand-independent way from the plasma membrane to endocytic compartments where chemokines are targeted to degradation. In vitro and in vivo evidence, including results with gene-targeted mice, is consistent with the view that D6 acts as a decoy and scavenger for inflammatory CC chemokines. ...
D6 binds most inflammatory, but not homeostatic, CC chemokines and shuttles in a ligand-independent way from the plasma membrane to e …
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