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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 2
1991 5
1992 11
1993 23
1994 24
1995 25
1996 23
1997 39
1998 26
1999 34
2000 34
2001 57
2002 44
2003 53
2004 45
2005 56
2006 73
2007 63
2008 83
2009 93
2010 86
2011 127
2012 115
2013 113
2014 148
2015 160
2016 129
2017 145
2018 102
2019 46
2020 0
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1,759 results
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Page 1
CXC-chemokines, a new group of cytokines in congestive heart failure--possible role of platelets and monocytes.
Damås JK, et al. Cardiovasc Res 2000. PMID 10728363
OBJECTIVES: The purpose of the present study was to examine the circulating levels of CXC-chemokines in patients with various degree of congestive heart failure (CHF). ...(iii) Both unstimulated and lipopolysaccharide (LPS)-stimulated monocytes from CHF patients released markedly elevated amounts of all three CXC-chemokines. ...
OBJECTIVES: The purpose of the present study was to examine the circulating levels of CXC-chemokines in patients with various …
MIG in psoriatic arthritis
Elia G. Clin Ter 2018 - Review. PMID 30554252 Free article.
It was demonstrated that both blood plasma-derived dendritic cells (pDCs) and pDCs isolated from rheumatoid arthritis (RA) and PsA synovial fluid (SF), expressed CXC receptor (R) 3 and CXCR4, and that the chemotaxis of blood-derived pDCs is stimulated by MIG, (IFN)-γ-inducible protein 10 (IP-10)/CXCL10, IFN-inducible T-cell α chemoattractant (I-TAC) )/CXCL11 and stromal cell-derived factor 1 (SDF-1)/ CXCL12, present in RA and PsA SF. In PsA patients have been found a Th1 immune predominance at early stage of disease, while a reduction of these chemokines has been observed in long lasting PsA, with a significant increase of monocyte chemoattractant protein-1/IP-10 ratio. ...
It was demonstrated that both blood plasma-derived dendritic cells (pDCs) and pDCs isolated from rheumatoid arthritis (RA) and PsA sy …
Diagnostic Value of Circulating CXC Chemokines in Non-small Cell Lung Cancer.
Spaks A, et al. Anticancer Res 2015. PMID 26637925
BACKGROUND/AIM: To evaluate the diagnostic value of circulating CXC chemokines as biomarkers for non-small cell lung cancer and compare them against a standard panel of already existing cancer biomarkers. ...The biomarkers levels were measured in plasma blood samples, by ELISA and immunoassays. RESULTS: The levels of circulating CXCL4, CXCL8, CXCL9, CXCL10 and CXCL11 were higher and those of circulating CXCL1 were lower in patients with early-stage NSCLC compared to metastatic NSCLC patients and controls (p<0.05). ...
BACKGROUND/AIM: To evaluate the diagnostic value of circulating CXC chemokines as biomarkers for non-small cell lung cancer an …
Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean section
Jakobsson HE, et al. Gut 2014. PMID 23926244 Free article.
Venous blood levels of Th1- and Th2-associated chemokines were measured at 6, 12 and 24 months. RESULTS: Infants born through CS had lower total microbiota diversity during the first 2 years of life. ...Infants born through CS had significantly lower levels of the Th1-associated chemokines CXCL10 and CXCL11 in blood. CONCLUSIONS: CS was associated with a lower total microbial diversity, delayed colonisation of the Bacteroidetes phylum and reduced Th1 responses during the first 2 years of life....
Venous blood levels of Th1- and Th2-associated chemokines were measured at 6, 12 and 24 months. RESULTS: Infants born through …
Overproduction of CXC chemokines CXCL1, CXCL9, CXCL10 and CXCL12 in β-thalassemia major or patients.
Najmaddini H, et al. Ann Saudi Med 2014. PMID 24894780 Free PMC article.
Therefore, the present study aimed to examine whether serum CXC chemokines are altered in b-thalassemia major patients. DESIGN AND SETTINGS: We enrolled 63 b-thalassemia patients and 80 controls in this cross-sectional study, which was performed during 2012-2013 in Kerman, Iran. ...The circulating levels of CXCL1, CXCL9, CXCL10, and CXCL12 were detected by enzyme-linked immunosorbent assay in thalassemia patients and healthy controls immediately after blood collection. ...
Therefore, the present study aimed to examine whether serum CXC chemokines are altered in b-thalassemia major patients. DESIGN …
Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis
van Bon L, et al. N Engl J Med 2014. PMID 24350901 Free PMC article.
Among chemokines, only CXCL4 predicted the risk and progression of systemic sclerosis. In vitro, CXCL4 down-regulated expression of transcription factor FLI1, induced markers of endothelial-cell activation, and potentiated responses of toll-like receptors. ...
Among chemokines, only CXCL4 predicted the risk and progression of systemic sclerosis. In vitro, CXCL4 down-regulated expression of t …
Role of chemokines and the corresponding receptors in vitiligo: A pilot study.
Yang L, et al. J Dermatol 2018. PMID 29115683
Then, the local epidermis levels of elevated chemokines in vitiligo were tested by Luminex. Finally, the mRNA and protein expression levels of elevated chemokines in HaCaT cells stimulated with interferon (IFN)-γ or tumor necrosis factor (TNF)-α were tested by quantitative real-time polymerase chain reaction and Luminex. ...In the peripheral blood of active vitiligo patients, the percentages of CD3(+) CD8(+) CCR5(+) and CD3(+) CD8(+) CXCR3(+) T cells were significantly increased compared with those in stable vitiligo and healthy controls. ...
Then, the local epidermis levels of elevated chemokines in vitiligo were tested by Luminex. Finally, the mRNA and protein expression …
Validation of a Novel Assay to Distinguish Bacterial and Viral Infections
Srugo I, et al. Pediatrics 2017 - Clinical Trial. PMID 28904072 Free article.
A novel assay that integrates measurements of blood-borne host-proteins (tumor necrosis factor-related apoptosis-inducing ligand, interferon γ-induced protein-10, and C-reactive protein [CRP]) was developed to assist in differentiation between bacterial and viral disease. ...
A novel assay that integrates measurements of blood-borne host-proteins (tumor necrosis factor-related apoptosis-inducing ligand, int …
Serum CXCL10, CXCL11, CXCL12, and CXCL14 chemokine patterns in patients with acute liver injury
Chalin A, et al. Cytokine 2018. PMID 29880273 Free article.
METHODS: We analyzed the serum concentration of the studied chemokines in healthy donors (n = 36) and patients (n = 163) with acute liver injuries of various etiologies. ...CXCL10, CXCL11 and CXCL12 were the most highly represented and CXCL14 the least represented chemokines. Differential expression patterns were obtained depending on acute liver injury etiology, suggesting the potential use of these chemokines as acute liver injury biomarkers....
METHODS: We analyzed the serum concentration of the studied chemokines in healthy donors (n = 36) and patients (n = 163) with acute l …
MIG in Crohn's disease
Caruso C. Clin Ter 2019 - Review. PMID 31173051 Free article.
CXCR3 and its chemokines expression were induced by IFN-γ in epithelial intestinal cells. These chemokines are involved in the recruitment of granulocytes and mononuclear cells, therefore in the maintenance of inflammation in CD. ...
CXCR3 and its chemokines expression were induced by IFN-γ in epithelial intestinal cells. These chemokines are involved in the …
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