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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1982 2
1983 6
1984 162
1985 410
1986 378
1987 334
1988 376
1989 388
1990 441
1991 487
1992 539
1993 495
1994 489
1995 549
1996 514
1997 516
1998 549
1999 591
2000 712
2001 752
2002 765
2003 819
2004 841
2005 903
2006 961
2007 908
2008 969
2009 1003
2010 1032
2011 1085
2012 1074
2013 1288
2014 1281
2015 1172
2016 1031
2017 873
2018 802
2019 345
2020 3
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23,686 results
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Page 1
MediterrAsian Diet Products That Could Raise HDL-Cholesterol: A Systematic Review.
Rondanelli M, et al. Biomed Res Int 2016 - Review. PMID 27882320 Free PMC article.
High HDL-cholesterol (HDL-C) values are negatively correlated with cardiovascular diseases. This review analyses the effect of the supplementation with various Mediterranean diet products (artichoke, bergamot, and olive oil) and Asian diet products (red yeast rice) on the HDL-C value in dyslipidemic subjects. ...Various MediterrAsian diet products or natural extracts may represent a potential intervention treatment to raise HDL-C in dyslipidemic subjects....
High HDL-cholesterol (HDL-C) values are negatively correlated with cardiovascular diseases. This review analyses the ef …
[Efficacy of pitavastatin on HDL-cholesterol].
Tokgözoğlu L. Turk Kardiyol Dern Ars 2017. PMID 28952471 Turkish. Free article.
Epidemiological studies have shown that low HDL predicts cardiovascular risk just as much as elevated LDL cholesterol levels. However, today we know that HDL functionality is more important than HDL levels. As a group effect, statins increase HDL levels. ...
Epidemiological studies have shown that low HDL predicts cardiovascular risk just as much as elevated LDL cholesterol levels. …
Niacin Therapy, HDL Cholesterol, and Cardiovascular Disease: Is the HDL Hypothesis Defunct?
Mani P and Rohatgi A. Curr Atheroscler Rep 2015 - Review. PMID 26048725 Free PMC article.
High-density lipoprotein cholesterol (HDL-C) has been shown in epidemiologic studies to be associated with cardiovascular (CV) risk and thus significant efforts have been focused on HDL-C modulation. ...Although the HDL cholesterol hypothesis may be defunct, the HDL function hypothesis is now poised to be rigorously tested....
High-density lipoprotein cholesterol (HDL-C) has been shown in epidemiologic studies to be associated with cardiovascular (CV) …
HDL Cholesterol as a Marker of Disease Severity and Prognosis in Patients with Pulmonary Arterial Hypertension.
Jonas K and Kopeć G. Int J Mol Sci 2019 - Review. PMID 31323735 Free PMC article.
The impact of high-density lipoprotein (HDL) cholesterol on the development of atherosclerosis and diseases of systemic circulation has been well documented both in experimental and registry studies. ...This paper reviews potential vasoprotective mechanisms of HDL in pulmonary circulation and presents current clinical reports on the role of HDL in PAH patients....
The impact of high-density lipoprotein (HDL) cholesterol on the development of atherosclerosis and diseases of systemic circul …
Where next with HDL assays?
Niisuke K, et al. Curr Opin Lipidol 2018 - Review. PMID 29846266
PURPOSE OF REVIEW: The inverse association between HDL cholesterol (HDL-C) and cardiovascular disease (CVD) has been unequivocally proven in the past several decades. ...RECENT FINDINGS: We have reviewed recent findings on HDL composition, HDL particle concentrations, and cell-cholesterol efflux capacity that have lately contributed to our understanding of HDL's role in CVD. ...
PURPOSE OF REVIEW: The inverse association between HDL cholesterol (HDL-C) and cardiovascular disease (CVD) has been un …
HDLs and the pathogenesis of atherosclerosis
Schwertani A, et al. Curr Opin Cardiol 2018 - Review. PMID 29561322
PURPOSE OF REVIEW: Plasma levels of HDL cholesterol are a biomarker of cardiovascular health but not a therapeutic target, as demonstrated by the failure of pharmacological modulation of HDL cholesterol to prevent or treat atherosclerotic cardiovascular disease. ...RECENT FINDINGS: These functional effects of HDL are independent of the cholesterol mass and are related to the proteome and lipidome. ...
PURPOSE OF REVIEW: Plasma levels of HDL cholesterol are a biomarker of cardiovascular health but not a therapeutic target, as …
What have we learnt from the clinical outcomes trials with the cetrapibs?
Doggrell SA. Curr Opin Lipidol 2018 - Review. PMID 29630000
PURPOSE OF REVIEW: The current review considers what we have learnt from the clinical outcome trials with the cetrapibs; the inhibitors of cholesteryl ester transfer protein that increase HDL cholesterol levels; torcetrapib, dalcetrapib, evacetrapib and anacetrapib. ...The success of anacetrapib in Randomized Evaluation of the Effects of Anacetrapib through Lipid Modification is more likely to have been due to lowering LDL cholesterol than to increasing HDL cholesterol. ...
PURPOSE OF REVIEW: The current review considers what we have learnt from the clinical outcome trials with the cetrapibs; the inhibitors of c …
Extremely elevated HDL-cholesterol levels are not associated with increased carotid intima-media thickness: data from ELSA Brasil.
Laurinavicius AG, et al. J Clin Lipidol 2016. PMID 27578121
BACKGROUND: There is evidence that extremely elevated high-density lipoprotein cholesterol (HDL-c), that is, hyperalphalipoproteinemia (HALP) may indicate dysfunctional HDL, conferring increased cardiovascular risk. ...METHODS: cIMT was studied in subjects with "normal" HDL-c levels (HDL-c 40-50 mg/dL for men; 50-60 mg/dL for women, mean 49.6 ± 5.7 mg/dL, n = 3226); in those with HALP (HDL-c ≥90 mg/dL for both sexes, mean 101.2 ± 10 mg/dL, n = 264) and according to HDL-c quintile distribution (n = 9779). ...
BACKGROUND: There is evidence that extremely elevated high-density lipoprotein cholesterol (HDL-c), that is, hyperalphalipopro …
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