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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 2
1950 1
1951 26
1952 80
1953 111
1954 79
1955 95
1956 133
1957 227
1958 251
1959 259
1960 281
1961 270
1962 337
1963 535
1964 700
1965 255
1966 46
1967 152
1968 258
1969 201
1970 167
1971 148
1972 182
1973 171
1974 200
1975 172
1976 199
1977 256
1978 240
1979 296
1980 394
1981 404
1982 402
1983 351
1984 334
1985 326
1986 342
1987 360
1988 463
1989 508
1990 560
1991 602
1992 572
1993 517
1994 509
1995 494
1996 423
1997 468
1998 460
1999 465
2000 572
2001 522
2002 557
2003 579
2004 624
2005 673
2006 658
2007 691
2008 708
2009 756
2010 731
2011 799
2012 829
2013 919
2014 976
2015 953
2016 841
2017 879
2018 851
2019 329
2020 7
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28,175 results
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Page 1
Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients.
Gerl MJ, et al. Sci Rep 2018. PMID 30282999 Free PMC article.
The concentration of lysophospatidylcholine (LPC) and ratios of concentrations of CE to free cholesterol (Chol) were also lower in the CVD cohorts than in the control cohort, indicating a deficient conversion of Chol to CE in the blood plasma in the CVD subjects. A non-equilibrium reaction quotient, Q', describing the global homeostasis of cholesterol as manifested in the blood plasma was shown to have a value in the CVD cohorts (Q'(ACS) = 0.217 ± 0.084; Q'(IS) = 0.201 ± 0.084; Q'(SAP) = 0.220 ± 0.071) that was about one third less than in the control cohort (Q'(Control) = 0.320 ± 0.095, p < 1 × 10(-4)), suggesting its potential use as a rapid predictive/diagnostic measure of CVD-related irregularities in cholesterol homeostasis....
The concentration of lysophospatidylcholine (LPC) and ratios of concentrations of CE to free cholesterol (Chol) were also lower in th …
Fractional cholesterol absorption measurements in humans: determinants of the blood-based dual stable isotope tracer technique.
Stellaard F and Lütjohann D. J Clin Lipidol 2015 - Review. PMID 25670356
FINDINGS: Seven different isotopic tracers, 3 cholesterol subcompartments in blood, and 6 mass spectrometry techniques were applied. ...Time points for blood sampling and methodologies for blood sample preparation and analysis were highly variable. No definite proofs were supplied for the fates of the oral and intravenous cholesterol tracers. ...
FINDINGS: Seven different isotopic tracers, 3 cholesterol subcompartments in blood, and 6 mass spectrometry techniques were ap …
[Introduction]
Seishima M. Rinsho Byori 2016 - Review. PMID 27192795 Japanese.
HDL removes free cholesterol from somatic cells by accepting cell cholesterol via ATP-binding cassette transporter A1. Cholesterol ester in HDL is transferred to VLDL and LDL by the action of cholesterol ester transfer protein or is incorporated into the liver via SR-BI. This pathway is called reverse cholesterol transport, which can regress atheromatous plaques. On the other hand, some CETP inhibitors, which can increase the HDL-C level have been developed in the world. ...
HDL removes free cholesterol from somatic cells by accepting cell cholesterol via ATP-binding cassette transporter A1. Chol
Blood cholesterol concentration: fingerstick plasma vs venous serum sampling.
Greenland P, et al. Clin Chem 1990. PMID 2323042 Free article.
To assess whether venous and fingerstick blood samples yield similar cholesterol concentrations, we obtained both types of samples simultaneously in 108 volunteers participating in a cholesterol screening program. ...Cholesterol values in fingerstick plasma also were higher than cholesterol results for venous serum placed in a capillary collection tube (average bias +2.4%). ...
To assess whether venous and fingerstick blood samples yield similar cholesterol concentrations, we obtained both types of sam …
The prevalence of high blood cholesterol levels among adults in the United States.
Sempos C, et al. JAMA 1989. PMID 2733124
Using the National Cholesterol Education Program's Guidelines for the Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults and the most recent nationally representative serum total cholesterol and lipoprotein data for adults (ages 20 to 74 years) from the second National Health and Nutrition Examination Survey (1976 to 1980), it is estimated that 41% of adults should have lipoprotein analysis after an initial measurement of serum total cholesterol. Furthermore, it is estimated that 88% of those who need lipoprotein analysis, or 36% of all adults aged 20 to 74 years, are candidates for medical advice and intervention for high blood cholesterol levels. ...
Using the National Cholesterol Education Program's Guidelines for the Detection, Evaluation, and Treatment of High Blood Ch
A Population-Based Study of Cholesterol Measurements in the Oldest Old.
Gils C, et al. Curr Aging Sci 2015. PMID 26329161
The need for cholesterol measurements is therefore also questionable, but the frequency of cholesterol measurements in the oldest old has not been described on a population basis. ...RESULTS: A total of 30,424 persons with a cholesterol measurement entered the study. The total number of cholesterol measurements increased by 246% during the observation period. ...
The need for cholesterol measurements is therefore also questionable, but the frequency of cholesterol measurements in the old …
[Changes in blood cholesterol levels over a 10-year period; value of a single sample for predicting future blood cholesterol levels].
Beurrier D, et al. Arch Mal Coeur Vaiss 1995. PMID 7487325 French.
The aim of this study was to report the serum cholesterol changes over a 10 year period in 12,238 subjects aged 4 to 64 years (mean 28 +/- 14 years) based on 3 health check-ups at an average of 5.5 yearly intervals between 1973 and 1989, and to determine the value of a single sample for predicting the serum cholesterol level at 5 and 10 years, and the influence of blood pressure and Quetelet index on this predictability. ...When the first two sampling results, five years apart, were taken into consideration simultaneously, the predictive value of having a raised cholesterol level at 10 years increased from 35 to 61%....
The aim of this study was to report the serum cholesterol changes over a 10 year period in 12,238 subjects aged 4 to 64 years (mean 2 …
Individual variation in serum cholesterol levels.
Hegsted DM and Nicolosi RJ. Proc Natl Acad Sci U S A 1987 - Review. PMID 3306674 Free PMC article.
The intraindividual variances in serum/plasma cholesterol levels from a variety of sources have been examined. It is apparent that these are very substantial with mean coefficients of variation usually between 5% and 10%, even when the diet is controlled in metabolic studies. Some subjects show extreme variability from one blood sample to the next. Thus, it is very difficult to assess the degree of risk of individuals according to the guidelines provided by the Consensus Conference on lowering blood cholesterol levels to prevent heart disease, and many individuals will be misclassified unless particular attention is paid to this problem....
The intraindividual variances in serum/plasma cholesterol levels from a variety of sources have been examined. It is apparent that th …
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