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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
1973 1
1975 5
1976 13
1977 12
1978 14
1979 23
1980 19
1981 21
1982 35
1983 43
1984 52
1985 61
1986 102
1987 81
1988 110
1989 123
1990 148
1991 156
1992 140
1993 168
1994 142
1995 238
1996 195
1997 201
1998 300
1999 379
2000 446
2001 431
2002 529
2003 620
2004 706
2005 783
2006 806
2007 953
2008 963
2009 979
2010 1114
2011 1213
2012 1263
2013 1484
2014 1519
2015 1611
2016 1447
2017 1499
2018 1391
2019 1415
2020 1452
2021 1614
2022 1501
2023 1354
2024 1471
2025 810

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29,128 results

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Page 1
Immune response and treatment targets of chronic hepatitis B virus infection: innate and adaptive immunity.
Zheng P, Dou Y, Wang Q. Zheng P, et al. Front Cell Infect Microbiol. 2023 Jun 22;13:1206720. doi: 10.3389/fcimb.2023.1206720. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37424786 Free PMC article. Review.
Chronic hepatitis B virus (HBV) infection is a major global public health risk that threatens human life and health, although the number of vaccinated people has increased. ...Although significant progress has been made in HBV treatment in recent years, the b …
Chronic hepatitis B virus (HBV) infection is a major global public health risk that threatens human life and health, al …
Chronic hepatitis B surface antigen seroclearance-related immune factors.
Yuan T, Jiang Y, Li M, Li W. Yuan T, et al. Hepatol Res. 2017 Jan;47(1):49-59. doi: 10.1111/hepr.12726. Epub 2016 May 26. Hepatol Res. 2017. PMID: 27084584 Review.
The immune factor interferon-alpha is currently the main antiviral therapy for chronic hepatitis B virus infection. However, a sustained shift from response of HBsAg to hepatitis B surface antibody seroconversion is rarely obtained. ...
The immune factor interferon-alpha is currently the main antiviral therapy for chronic hepatitis B virus infection. How …
Interferon and Hepatitis B: Current and Future Perspectives.
Ye J, Chen J. Ye J, et al. Front Immunol. 2021 Sep 7;12:733364. doi: 10.3389/fimmu.2021.733364. eCollection 2021. Front Immunol. 2021. PMID: 34557195 Free PMC article. Review.
Chronic hepatitis B virus (HBV) infection remains a major health burden worldwide for which there is still no effective curative treatment. ...IFN-alpha and its pegylated form have been used for over thirty years to treat chronic hepatitis B …
Chronic hepatitis B virus (HBV) infection remains a major health burden worldwide for which there is still no effective …
Management of chronic hepatitis B during pregnancy.
Aslam A, Campoverde Reyes KJ, Malladi VR, Ishtiaq R, Lau DTY. Aslam A, et al. Gastroenterol Rep (Oxf). 2018 Nov;6(4):257-262. doi: 10.1093/gastro/goy025. Epub 2018 Jul 24. Gastroenterol Rep (Oxf). 2018. PMID: 30430013 Free PMC article. Review.
Chronic hepatitis B is globally prevalent and is a major cause of cirrhosis and hepatocellular carcinoma. ...In this review, we summarize the current treatment options for chronic hepatitis B with a focus on management during pregnancy an …
Chronic hepatitis B is globally prevalent and is a major cause of cirrhosis and hepatocellular carcinoma. ...In this re …
Chronic hepatitis B in 2014: great therapeutic progress, large diagnostic deficit.
Niederau C. Niederau C. World J Gastroenterol. 2014 Sep 7;20(33):11595-617. doi: 10.3748/wjg.v20.i33.11595. World J Gastroenterol. 2014. PMID: 25206267 Free PMC article. Review.
Despite the success of vaccination and therapy chronic hepatitis B remains a problem since many infected patients do not know of their disease. ...Despite the success of vaccination and therapy chronic hepatitis B infection remains a majo …
Despite the success of vaccination and therapy chronic hepatitis B remains a problem since many infected patients do no …
Immunopathogenesis of Acute Flare of Chronic Hepatitis B: With Emphasis on the Role of Cytokines and Chemokines.
Liu C, Shih YF, Liu CJ. Liu C, et al. Int J Mol Sci. 2022 Jan 26;23(3):1407. doi: 10.3390/ijms23031407. Int J Mol Sci. 2022. PMID: 35163330 Free PMC article. Review.
Acute flares (AFs) of chronic hepatitis B usually occur during the immune-active stage (both immune clearance phase and immune reactivation phase), as the host immune system tries to control the virus. ...AF can also develop in other clinical situations such …
Acute flares (AFs) of chronic hepatitis B usually occur during the immune-active stage (both immune clearance phase and …
Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China.
Yu R, Fan R, Hou J. Yu R, et al. Front Med. 2014 Jun;8(2):135-44. doi: 10.1007/s11684-014-0331-5. Epub 2014 May 8. Front Med. 2014. PMID: 24810645 Review.
Chronic hepatitis B is a major health problem in China. The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infection in China from highly to moderately endemic. The most prevalent hepatitis B virus strains in China …
Chronic hepatitis B is a major health problem in China. The universal vaccination program since 1992 has changed the ep …
Overview of chronic hepatitis B management.
Jun A, Bau S, Kim JS, Phillips SJ. Jun A, et al. Nurse Pract. 2025 Jan 1;50(1):7-13. doi: 10.1097/01.NPR.0000000000000246. Epub 2024 Dec 19. Nurse Pract. 2025. PMID: 39696735 Free PMC article. Review.
Chronic hepatitis B remains a substantial global health challenge, impacting approximately 254 million people worldwide. ...
Chronic hepatitis B remains a substantial global health challenge, impacting approximately 254 million people worldwide …
Screening for Hepatocellular Carcinoma in Chronic Hepatitis B: An Update.
Lok J, Agarwal K. Lok J, et al. Viruses. 2021 Jul 10;13(7):1333. doi: 10.3390/v13071333. Viruses. 2021. PMID: 34372539 Free PMC article. Review.
(1) Background: Hepatocellular carcinoma (HCC) is an important cause of mortality in individuals with chronic hepatitis B infection, with screening of high-risk groups recommended in all major international guidelines. ...In recent studies, novel viral biomar …
(1) Background: Hepatocellular carcinoma (HCC) is an important cause of mortality in individuals with chronic hepatitis B …
29,128 results
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