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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
2001 1
2004 4
2005 2
2008 2
2010 9
2011 184
2012 361
2013 435
2014 487
2015 501
2016 568
2017 537
2018 539
2019 264
2020 4
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3,426 results
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Page 1
Cannabis and Cannabinoids for Chronic Pain.
Romero-Sandoval EA, et al. Curr Rheumatol Rep 2017 - Review. PMID 28983880
RECENT FINDINGS: We found that inhaled (smoked or vaporized) cannabis is consistently effective in reducing chronic non-cancer pain. Oral cannabinoids seem to improve some aspects of chronic pain (sleep and general quality of life), or cancer chronic pain, but they do not seem effective in acute postoperative pain, abdominal chronic pain, or rheumatoid pain. ...
RECENT FINDINGS: We found that inhaled (smoked or vaporized) cannabis is consistently effective in reducing chronic non-cancer pai
An overview of treatment approaches for chronic pain management.
Hylands-White N, et al. Rheumatol Int 2017 - Review. PMID 27107994
Pain which persists after healing is expected to have taken place, or which exists in the absence of tissue damage, is termed chronic pain. By definition chronic pain cannot be treated and cured in the conventional biomedical sense; rather, the patient who is suffering from the pain must be given the tools with which their long-term pain can be managed to an acceptable level. ...
Pain which persists after healing is expected to have taken place, or which exists in the absence of tissue damage, is termed chro
[Chronic pain therapy in inflammatory rheumatic diseases].
Suchý D and Lejčko J. Vnitr Lek 2018. PMID 29595274 Czech.
Chronic pain is a common health problem related to most of inflammatory rheumatic disorders. It is pain that has persisted for at least 3 month and cannot be fully relieved by standard pain medication. 40-60 % of patients do not have adequate relief of their pain. Paramount in the management of chronic pain patients is assessment of the pain and its impact on physical and psychosocial functioning. ...
Chronic pain is a common health problem related to most of inflammatory rheumatic disorders. It is pain that has persis
Prescription Opioid Abuse in Chronic Pain: An Updated Review of Opioid Abuse Predictors and Strategies to Curb Opioid Abuse: Part 1.
Kaye AD, et al. Pain Physician 2017 - Review. PMID 28226333 Free article.
There is a significant need for treatment approaches that balance treating chronic pain; while minimizing risks for opioid abuse, misuse, and diversion. The use of chronic opioid therapy for chronic non-cancer pain has increased dramatically in the past 2 decades in conjunction with associated increases in the abuse of prescribed opioids and accidental opioid overdoses. ...
There is a significant need for treatment approaches that balance treating chronic pain; while minimizing risks for opioid abu …
Multimodal Treatment of Chronic Pain.
Dale R and Stacey B. Med Clin North Am 2016 - Review. PMID 26614719
Chronic pain often leads to depression, anxiety, and deconditioning, which are targets for treatment. Structured interdisciplinary programs are beneficial but costly. Interventions have their place in the treatment of chronic pain and should be a part of a multidisciplinary treatment plan. Further research is needed to validate many common combination treatments....
Chronic pain often leads to depression, anxiety, and deconditioning, which are targets for treatment. Structured interdiscipli
Animal models of chronic pain: Advances and challenges for clinical translation.
Burma NE, et al. J Neurosci Res 2017 - Review. PMID 27376591
Chronic pain is a global problem that has reached epidemic proportions. An estimated 20% of adults suffer from pain, and another 10% are diagnosed with chronic pain each year (Goldberg and McGee, ). ...This review discusses common animal models used to recapitulate clinical chronic pain conditions (such as neuropathic, inflammatory, and visceral pain) and the methods for assessing the sensory and affective components of pain in animals. ...
Chronic pain is a global problem that has reached epidemic proportions. An estimated 20% of adults suffer from pain, an
MicroRNA and chronic pain: From mechanisms to therapeutic potential.
López-González MJ, et al. Pharmacol Ther 2017 - Review. PMID 28579386
Unfortunately, few patients with chronic pain obtain complete relief from the analgesics that are currently available. It is thus of prime importance to get a better understanding of chronic pain mechanisms to design new therapeutic strategies and pain-killers. ...The involvement of miRNAs in the maladaptive plasticity mechanisms of chronic pain is now well documented. Here, we review studies conducted in different animal models and in patients that screened chronic pain-related miRNAs and their targets. ...
Unfortunately, few patients with chronic pain obtain complete relief from the analgesics that are currently available. …
Medical Cannabis in Patients with Chronic Pain: Effect on Pain Relief, Pain Disability, and Psychological aspects. A Prospective Non randomized Single Arm Clinical Trial.
Poli P, et al. Clin Ter 2018 - Clinical Trial. PMID 29938740 Free article.
BACKGROUND: There is an increasing interest in the medical use of cannabis, particularly in the treatment of chronic pain. OBJECTIVES: The aim is to evaluate the effects of cannabis use and the associated benefits reported by patients with various chronic pain diagnoses. ...CONCLUSIONS: Our study suggest that Cannabis therapy, as an adjun- ct a traditional analgesic therapy, can be an efficacious tool to make more effective the management of chronic pain and its consequences on functional and psychological dimension. ...
BACKGROUND: There is an increasing interest in the medical use of cannabis, particularly in the treatment of chronic pain
Cannabis for Chronic Pain: Challenges and Considerations.
Romero-Sandoval EA, et al. Pharmacotherapy 2018 - Review. PMID 29637590
The National Academies of Sciences, Engineering, and Medicine has found substantial evidence that cannabis (plant) is effective for the treatment of chronic pain in adults, and moderate evidence that oromucosal cannabinoids (extracts, especially nabiximols) improve short-term sleep disturbances in chronic pain. ...Cannabis designed for recreational use (containing high levels of active ingredients) is increasingly available to patients with chronic pain who do not find relief with current pharmacologic entities, which exposes patients to potential harm. ...
The National Academies of Sciences, Engineering, and Medicine has found substantial evidence that cannabis (plant) is effective for the trea …
European Pain Federation (EFIC) position paper on appropriate use of cannabis-based medicines and medical cannabis for chronic pain management.
Häuser W, et al. Eur J Pain 2018. PMID 30074291
The quantity and quality of evidence are such that cannabis-based medicines may be reasonably considered for chronic neuropathic pain. For all other chronic pain conditions (cancer, non-neuropathic noncancer pain), the use of cannabis-based medicines should be regarded as an individual therapeutic trial. ...
The quantity and quality of evidence are such that cannabis-based medicines may be reasonably considered for chronic neuropathic p
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