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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 5
1946 1
1947 10
1948 9
1949 24
1950 38
1951 51
1952 50
1953 60
1954 57
1955 78
1956 73
1957 76
1958 94
1959 76
1960 103
1961 132
1962 141
1963 236
1964 391
1965 351
1966 367
1967 496
1968 626
1969 707
1970 819
1971 864
1972 1035
1973 989
1974 1106
1975 1025
1976 900
1977 909
1978 923
1979 959
1980 1136
1981 1108
1982 1129
1983 1121
1984 1355
1985 1348
1986 1453
1987 1330
1988 1560
1989 1627
1990 1805
1991 1943
1992 1981
1993 2012
1994 2046
1995 2157
1996 2243
1997 2241
1998 2349
1999 2273
2000 2521
2001 2398
2002 1982
2003 1984
2004 2037
2005 2145
2006 2126
2007 2180
2008 2450
2009 2524
2010 2737
2011 2803
2012 2918
2013 3136
2014 2980
2015 2976
2016 2749
2017 2699
2018 2500
2019 1192
2020 29
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91,237 results
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Page 1
Myasthenia gravis
Gilhus NE, et al. Nat Rev Dis Primers 2019 - Review. PMID 31048702
Corneal Collagen Cross-Linking in the Stabilization of Keratoconus.
Maier P, et al. Dtsch Arztebl Int 2019 - Review. PMID 31014449 Free PMC article.
Riboflavin-UVA crosslinking (collagen cross-linking) makes corneal tissue more rigid through a photochemical effect and can stop the progression of the disease. ...
Riboflavin-UVA crosslinking (collagen cross-linking) makes corneal tissue more rigid through a photochemical effect and can stop the …
Molecular Mechanisms of Dermal Aging and Antiaging Approaches
Shin JW, et al. Int J Mol Sci 2019 - Review. PMID 31036793 Free PMC article.
Collagen, which is a major component of ECM, becomes fragmented and coarsely distributed, and its total amount decreases. This is mainly due to increased activity of matrix metalloproteinases, and impaired transforming growth factor-β signaling induced by reactive oxygen species generated during aging. The reduction in the amount of collagen hinders the mechanical interaction between fibroblasts and the ECM, and consequently leads to the deterioration of fibroblast function and further decrease in the amount of dermal collagen. ...
Collagen, which is a major component of ECM, becomes fragmented and coarsely distributed, and its total amount decreases. This is mai
A structural prospective for collagen receptors such as DDR and their binding of the collagen fibril.
Orgel JPRO and Madhurapantula RS. Biochim Biophys Acta Mol Cell Res 2019 - Review. PMID 31004686
The structure of the collagen fibril surface directly effects and possibly assists the management of collagen receptor interactions. ...This review discusses their structure and function as it pertains directly to the fibrillar collagen structure with which they interact far more readily than they do with isolated molecular collagen. ...
The structure of the collagen fibril surface directly effects and possibly assists the management of collagen receptor interac …
Evidence of biomechanical and collagen heterogeneity in uterine fibroids.
Jayes FL, et al. PLoS One 2019. PMID 31034494 Free PMC article.
All examined fibroids contained at least 37% collagen. Tested samples included type I, III, and V collagen of different proportions. Fibroid stiffness was not correlated with the overall collagen content (correlation coefficient 0.22). Neither stiffness nor collagen content was correlated with fibroid size. ...
All examined fibroids contained at least 37% collagen. Tested samples included type I, III, and V collagen of different propor …
Measured collagen fibril response to arterial inflation using SAXS.
Wells HC, et al. Int J Biol Macromol 2019. PMID 31295493
Here we use small angle X-ray scattering to investigate the changes in arrangement of collagen fibrils and the strain experienced by collagen fibrils as arteries are inflated. Collagen fibrils re-orient to become more aligned in both the annular direction and radially as arteries inflate. With arterial pressures up to 32 kPa there is no observable increase in D-spacing of the collagen fibrils (<0.1%) indicating that there is no extension of straightened fibrils and therefore no change in stress on the collagen fibrils. ...
Here we use small angle X-ray scattering to investigate the changes in arrangement of collagen fibrils and the strain experienced by …
Marine Collagen as A Promising Biomaterial for Biomedical Applications.
Lim YS, et al. Mar Drugs 2019 - Review. PMID 31405173 Free PMC article.
This review focuses on the expanding role of marine collagen (MC)-based scaffolds for biomedical applications. A scaffold-a three-dimensional (3D) structure fabricated from biomaterials-is a key supporting element for cell attachment, growth, and maintenance in 3D cell culture and tissue engineering. ...MC, collagen derived from marine organisms, offers advantages over mammalian collagen due to its biocompatibility, biodegradability, easy extractability, water solubility, safety, low immunogenicity, and low production costs. ...
This review focuses on the expanding role of marine collagen (MC)-based scaffolds for biomedical applications. A scaffold-a three-dim …
Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung.
Lee YC, et al. Nat Commun 2019. PMID 31086186 Free PMC article.
Here, we showed that bladder tumor cells expressing the collagen receptor, CD167a, responded to collagen I stimulation at the primary tumor to promote local invasion and utilized the same receptor to preferentially colonize at airway smooth muscle cells (ASMCs)-a rich source of collagen III in lung. ...
Here, we showed that bladder tumor cells expressing the collagen receptor, CD167a, responded to collagen I stimulation at the …
Preparation of low-molecular-weight, collagen hydrolysates (peptides): Current progress, challenges, and future perspectives.
Hong H, et al. Food Chem 2019 - Review. PMID 31382108
Low-molecular-weight (LMW) collagen hydrolysates are generally thought to exert better bioactivities than their larger counterparts. ...We then discuss the challenges and then provide perspectives on future directions in preparing LMW collagen hydrolysates....
Low-molecular-weight (LMW) collagen hydrolysates are generally thought to exert better bioactivities than their larger counterparts. …
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