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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 37
1782 18
1783 22
1784 27
1785 43
1786 60
1787 43
1788 33
1789 32
1790 44
1791 19
1792 33
1793 17
1794 18
1795 13
1796 15
1797 59
1798 15
1799 291
1800 377
1801 360
1802 283
1803 269
1804 289
1805 314
1806 282
1807 295
1808 289
1809 265
1810 267
1811 322
1812 238
1813 265
1814 285
1815 222
1816 315
1817 288
1818 303
1819 225
1820 213
1821 270
1822 247
1823 291
1824 269
1825 262
1826 385
1827 326
1828 467
1829 645
1830 569
1831 627
1832 313
1833 293
1834 287
1835 305
1836 271
1837 350
1838 484
1839 546
1840 695
1841 1154
1842 1488
1843 1118
1844 1248
1845 1278
1846 1406
1847 1367
1848 1204
1849 1208
1850 1127
1851 1228
1852 1310
1853 1559
1854 1306
1855 1587
1856 1587
1857 1488
1858 1542
1859 1562
1860 1632
1861 1275
1862 1112
1863 995
1864 1139
1865 1151
1866 1477
1867 1723
1868 1813
1869 1909
1870 1809
1871 2238
1872 2242
1873 2313
1874 2508
1875 2402
1876 2095
1877 2180
1878 2454
1879 2399
1880 2646
1881 3149
1882 2743
1883 3127
1884 3050
1885 3338
1886 3291
1887 3965
1888 4002
1889 4196
1890 4025
1891 3607
1892 4081
1893 4370
1894 3801
1895 4129
1896 4413
1897 4689
1898 4632
1899 4169
1900 3786
1901 3887
1902 3968
1903 3910
1904 4060
1905 4067
1906 3872
1907 4323
1908 4459
1909 4687
1910 4799
1911 5007
1912 4906
1913 5107
1914 5135
1915 4641
1916 4544
1917 4281
1918 4567
1919 4619
1920 4960
1921 4628
1922 4123
1923 4432
1924 4851
1925 4990
1926 5342
1927 5887
1928 5479
1929 5741
1930 5630
1931 5496
1932 5548
1933 5610
1934 5508
1935 5661
1936 5384
1937 5308
1938 5765
1939 5541
1940 4998
1941 4838
1942 4775
1943 4517
1944 4745
1945 20422
1946 53739
1947 64968
1948 70728
1949 62806
1950 85750
1951 103810
1952 108147
1953 108914
1954 105913
1955 108541
1956 107005
1957 111515
1958 109458
1959 109989
1960 112211
1961 120166
1962 125670
1963 141520
1964 162087
1965 176642
1966 179754
1967 191503
1968 207845
1969 215073
1970 218980
1971 222883
1972 227521
1973 230652
1974 234524
1975 248259
1976 250346
1977 249830
1978 258187
1979 265471
1980 267172
1981 271493
1982 283101
1983 294742
1984 302663
1985 318930
1986 331403
1987 347415
1988 363917
1989 378018
1990 383158
1991 381002
1992 382636
1993 390402
1994 402017
1995 411224
1996 421135
1997 418829
1998 436508
1999 453709
2000 490774
2001 503029
2002 520884
2003 548577
2004 591963
2005 650302
2006 697081
2007 733409
2008 781218
2009 821497
2010 884724
2011 960907
2012 1027074
2013 1078379
2014 1132542
2015 1175250
2016 1209188
2017 1232771
2018 1277532
2019 1338601
2020 1536231
2021 1680714
2022 1681012
2023 1594723
2024 1624968
2025 154979

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36,131,047 results

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Quoted phrase not found in phrase index: "Cell Strain Lncap"
Page 1
Sensitive detection of DNA oxidation damage induced by nanomaterials.
Collins A, El Yamani N, Dusinska M. Collins A, et al. Free Radic Biol Med. 2017 Jun;107:69-76. doi: 10.1016/j.freeradbiomed.2017.02.001. Epub 2017 Feb 2. Free Radic Biol Med. 2017. PMID: 28161308 Review.
They might in some cases have the potential to damage DNA directly, or could act via the induction of oxidative stress. The comet assay (single cell gel electrophoresis) is widely used to measure DNA strand breaks and also oxidised bases, by inc …
They might in some cases have the potential to damage DNA directly, or could act via the induction of oxidative stress. The …
Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals.
Møller P, Jensen DM, Christophersen DV, Kermanizadeh A, Jacobsen NR, Hemmingsen JG, Danielsen PH, Karottki DG, Roursgaard M, Cao Y, Jantzen K, Klingberg H, Hersoug LG, Loft S. Møller P, et al. Environ Mol Mutagen. 2015 Mar;56(2):97-110. doi: 10.1002/em.21899. Epub 2014 Sep 5. Environ Mol Mutagen. 2015. PMID: 25196723 Review.
In particular, 8-oxo-7,8-dihydroguanine-2'-deoxyguanosine (8-oxodG) is widely assessed as a DNA nucleobase oxidation product, measured by chromatographic assays, antibody-based methods or the comet assay with DNA repair enzymes. ...Oral exposure …
In particular, 8-oxo-7,8-dihydroguanine-2'-deoxyguanosine (8-oxodG) is widely assessed as a DNA nucleobase oxidation product, measure …
The antioxidant activity and genotoxicity of isogarcinol.
Liu Z, Li G, Long C, Xu J, Cen J, Yang X. Liu Z, et al. Food Chem. 2018 Jul 1;253:5-12. doi: 10.1016/j.foodchem.2018.01.074. Epub 2018 Jan 12. Food Chem. 2018. PMID: 29502843
The antioxidant activity and genotoxicity of isogarcinol were assessed by several in vitro tests. ...Isogarcinol had no cyctotoxic or promotional activities at 1-10 M in the CCK-8 assay, and negligible genotoxic effects at 50-500 M on HepG2 cells by th …
The antioxidant activity and genotoxicity of isogarcinol were assessed by several in vitro tests. ...Isogarcinol had no …
Metformin-induced oxidative stress inhibits LNCaP prostate cancer cell survival.
Dixon S, Tran A, Schrier MS, Dong J, Deth RC, Castejon A, Trivedi MS. Dixon S, et al. Mol Biol Rep. 2024 Jun 12;51(1):729. doi: 10.1007/s11033-024-09662-8. Mol Biol Rep. 2024. PMID: 38862809
Notably, these studies demonstrated metformin's pleiotropic effects on several molecular and metabolic pathways, such as androgen signaling, cell cycle, and cellular bioenergetics. In this study we investigated the role of metformin in regulating intracellular redox status …
Notably, these studies demonstrated metformin's pleiotropic effects on several molecular and metabolic pathways, such as androgen signaling, …
Oxidative stress induces mitochondrial DNA damage and cytotoxicity through independent mechanisms in human cancer cells.
Han Y, Chen JZ. Han Y, et al. Biomed Res Int. 2013;2013:825065. doi: 10.1155/2013/825065. Epub 2012 Dec 26. Biomed Res Int. 2013. PMID: 23509785 Free PMC article. Review.
Intrinsic oxidative stress through increased production of reactive oxygen species (ROS) is associated with carcinogenic transformation, cell toxicity, and DNA damage. Mitochondrial DNA (mtDNA) is a natural surrogate to oxidative DNA damage …
Intrinsic oxidative stress through increased production of reactive oxygen species (ROS) is associated with carcinogenic trans …
The human prostatic carcinoma cell line LNCaP and its derivatives. An overview.
van Steenbrugge GJ, Groen M, van Dongen JW, Bolt J, van der Korput H, Trapman J, Hasenson M, Horoszewicz J. van Steenbrugge GJ, et al. Urol Res. 1989;17(2):71-7. doi: 10.1007/BF00262024. Urol Res. 1989. PMID: 2660395 Review.
The FGC (fast growing colony) line, a derivative of the LNCaP cell line shares all the main characteristics, including its androgen dependence, described for the original LNCaP cultures. ...Distinct morphological differences were observed between the …
The FGC (fast growing colony) line, a derivative of the LNCaP cell line shares all the main characteristics, including …
Androprostamine A: a unique antiprostate cancer agent.
Yamazaki Y, Abe H, Sakashita C, Ohba SI, Watanabe T, Momose I, Kawada M. Yamazaki Y, et al. J Antibiot (Tokyo). 2021 Oct;74(10):717-725. doi: 10.1038/s41429-021-00449-8. Epub 2021 Jul 28. J Antibiot (Tokyo). 2021. PMID: 34321608
The androgen receptor (AR) is an important therapeutic target for all clinical states of prostate cancer. We screened cultured broths of microorganisms for their ability to suppress androgen-dependent growth of human prostate cancer LNCaP and VCaP cells …
The androgen receptor (AR) is an important therapeutic target for all clinical states of prostate cancer. We screened cultured broths …
Antioxidant, Cytotoxic, Genotoxic, and DNA-Protective Potential of 2,3-Substituted Quinazolinones: Structure-Activity Relationship Study.
Hricovíniová J, Hricovíniová Z, Kozics K. Hricovíniová J, et al. Int J Mol Sci. 2021 Jan 9;22(2):610. doi: 10.3390/ijms22020610. Int J Mol Sci. 2021. PMID: 33435390 Free PMC article.
Therefore, a series of 2,3-substituted quinazolinone derivatives (Q1-Q8) were investigated by different assays, and the relationship between their biological properties and chemical structure was examined. Genotoxicity and the potential DNA-protective effects of Q1-Q8 were …
Therefore, a series of 2,3-substituted quinazolinone derivatives (Q1-Q8) were investigated by different assays, and the relationship between …
36,131,047 results
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