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Year Number of Results
2004 1
2006 2
2007 8
2008 32
2009 94
2010 106
2011 104
2012 79
2013 88
2014 80
2015 61
2016 45
2017 32
2018 23
2019 12
2020 0
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Array-Based Comparative Genomic Hybridization (aCGH).
Zhang C, et al. Methods Mol Biol 2017. PMID 27910023
A number of assays have been developed for the detection of CNVs, including fluorescent in situ hybridization (FISH), array-based comparative genomic hybridization (aCGH), PCR-based assays, and next-generation sequencing (NGS). ...
A number of assays have been developed for the detection of CNVs, including fluorescent in situ hybridization (FISH), array-based …
Array comparative genomic hybridization and genomic sequencing in the diagnostics of the causes of congenital anomalies.
Szczałuba K and Demkow U. J Appl Genet 2017 - Review. PMID 27858254
Array comparative genomic hybridization and next-generation sequencing have revolutionized the clinical approach to patients with these phenotypes. ...The application of both complementary methods could assist in identifying many variants that may simultaneously be involved in the development of a number of isolated or multiple congenital anomalies. ...
Array comparative genomic hybridization and next-generation sequencing have revolutionized the clinical approach to pat …
Centralization errors in comparative genomic hybridization array analysis of pituitary tumor samples.
Lasolle H, et al. Genes Chromosomes Cancer 2018. PMID 29460398
Reliable interpretation of comparative genomic hybridization array (aCGH) results requires centralization and normalization of the data. ...In these tumors, which can exhibit many changes in DNA copy number, we found that centralization bias was frequent and uncorrected by current normalization methods. ...
Reliable interpretation of comparative genomic hybridization array (aCGH) results requires centralization and normaliza …
The Diagnostic Yield of Array Comparative Genomic Hybridization Is High Regardless of Severity of Intellectual Disability/Developmental Delay in Children.
D'Arrigo S, et al. J Child Neurol 2016. PMID 26511719
Microarray-based comparative genomic hybridization is a method of molecular analysis that identifies chromosomal anomalies (or copy number variants) that correlate with clinical phenotypes. ...We want to emphasize the need to conduct microarray-based comparative genomic hybridization on all individuals with intellectual disability/developmental delay, regardless of the severity, because the degree of intellectual disability/developmental delay does not predict the diagnostic yield of microarray-based comparative genomic hybridization....
Microarray-based comparative genomic hybridization is a method of molecular analysis that identifies chromosomal anomal …
Application of Array Comparative Genomic Hybridization in Newborns with Multiple Congenital Anomalies.
Szczałuba K, et al. Adv Exp Med Biol 2016. PMID 26987320
Some of their genetic causes are attributable to copy number variations identified by array comparative genomic hybridization (aCGH). ...The aim of the study was to determine the optimal quality and clinical sensitivity of high-resolution array comparative genomic hybridization in neonates with multiple congenital anomalies. ...
Some of their genetic causes are attributable to copy number variations identified by array comparative genomic hybridizati
[Array-comparative genomic hybridization is a new and promising method for prenatal chromosomal diagnosis].
Nørgaard LN, et al. Ugeskr Laeger 2014 - Review. PMID 25292226 Danish.
Array-comparative genomic hybridization (array-CGH) is a very sensitive method for identifying chromosomal imbalances and is now used on a clinical basis for prenatal diagnosis. ...
Array-comparative genomic hybridization (array-CGH) is a very sensitive method for identifying chromosomal imbalances a …
Array comparative genomic hybridization findings in a cohort referred for an autism evaluation.
Schaefer GB, et al. J Child Neurol 2010. PMID 20729506
The development and refinement of array comparative genomic hybridization has led to expanded applications as a diagnostic tool. Recent reports suggest a high diagnostic yield for array comparative genomic hybridization in autism spectrum disorders. The objective of this study was to determine the diagnostic yield in array comparative genomic hybridization for autism at the University of Nebraska Medical Center. ...
The development and refinement of array comparative genomic hybridization has led to expanded applications as a diagnos …
Application of array comparative genomic hybridization in 256 patients with developmental delay or intellectual disability.
Bartnik M, et al. J Appl Genet 2014. PMID 24297458 Free PMC article.
We used whole-genome exon-targeted oligonucleotide array comparative genomic hybridization (array CGH) in a cohort of 256 patients with developmental delay (DD)/intellectual disability (ID) with or without dysmorphic features, additional neurodevelopmental abnormalities, and/or congenital malformations. ...
We used whole-genome exon-targeted oligonucleotide array comparative genomic hybridization (array CGH) in a cohort of 2 …
Microarray-based comparative genomic hybridization analysis in neonates with congenital anomalies: detection of chromosomal imbalances.
Emy Dorfman L, et al. J Pediatr (Rio J) 2015. PMID 25203518 Free article.
OBJECTIVE: To identify chromosomal imbalances by whole-genome microarray-based comparative genomic hybridization (array-CGH) in DNA samples of neonates with congenital anomalies of unknown cause from a birth defects monitoring program at a public maternity hospital. METHODS: A blind genomic analysis was performed retrospectively in 35 stored DNA samples of neonates born between July of 2011 and December of 2012. ...
OBJECTIVE: To identify chromosomal imbalances by whole-genome microarray-based comparative genomic hybridization (array …
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