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41,610 results

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Quoted phrase not found in phrase index: "Convulsions generalised"
Page 1
Therapeutic Basis of Generic Substitution of Antiseizure Medications.
Elmer S, Reddy DS. Elmer S, et al. J Pharmacol Exp Ther. 2022 May;381(2):188-196. doi: 10.1124/jpet.121.000994. Epub 2022 Mar 3. J Pharmacol Exp Ther. 2022. PMID: 35241634 Free PMC article. Review.
Moreover, nearly 30% of people with epilepsy have drug-resistant or intractable seizures. Generic substitution of ASMs is a complex issue. It is thought that frequent generic substitution in people with epilepsy may cause problems because the U.S. ...There is …
Moreover, nearly 30% of people with epilepsy have drug-resistant or intractable seizures. Generic substitution of ASMs is a co …
Forebrain-independent generation of hyperthermic convulsions in infant rats.
Pospelov AS, Yukin AY, Blumberg MS, Puskarjov M, Kaila K. Pospelov AS, et al. Epilepsia. 2016 Jan;57(1):e1-6. doi: 10.1111/epi.13230. Epub 2015 Nov 7. Epilepsia. 2016. PMID: 26547277 Free PMC article.
Febrile seizures are the most common type of convulsive events in children. It is generally assumed that the generalization of these seizures is a result of brainstem invasion by the initial limbic seizure activity. ...The present data suggest t …
Febrile seizures are the most common type of convulsive events in children. It is generally assumed that the general …
Light-activated channels in acute seizures.
Kokaia M. Kokaia M. Epilepsia. 2011 Oct;52 Suppl 8:16-8. doi: 10.1111/j.1528-1167.2011.03226.x. Epilepsia. 2011. PMID: 21967352 Free article. Review.
Hallorhodopsin NpHR is an inward cholride pump, which when activated by orange light, hyperpolarises neuronal membrane and inhibitis action potential generation. We were first to show that transduction of principal neurons with NpHR in organotypic hippocampal slice culture …
Hallorhodopsin NpHR is an inward cholride pump, which when activated by orange light, hyperpolarises neuronal membrane and inhibitis action …
Generic substitution of antiepileptic drugs.
Sander JW, Ryvlin P, Stefan H, Booth DR, Bauer J. Sander JW, et al. Expert Rev Neurother. 2010 Dec;10(12):1887-98. doi: 10.1586/ern.10.163. Expert Rev Neurother. 2010. PMID: 21091318 Review.
Substitution of antiepileptic drugs with generic formulations may affect individual people, as well as healthcare systems. Analyses of large medical claims databases suggest that generic substitution of antiepileptic drugs is associated with increased …
Substitution of antiepileptic drugs with generic formulations may affect individual people, as well as healthcare systems. Ana …
Behavioral changes in models of chemoconvulsant-induced epilepsy: A review.
Minjarez B, Camarena HO, Haramati J, Rodríguez-Yañez Y, Mena-Munguía S, Buriticá J, García-Leal O. Minjarez B, et al. Neurosci Biobehav Rev. 2017 Dec;83:373-380. doi: 10.1016/j.neubiorev.2017.10.016. Epub 2017 Oct 28. Neurosci Biobehav Rev. 2017. PMID: 29107831 Review.
Epilepsy is one of the most common neurological disorders in the general population and affects over 50 million people worldwide. Epilepsy is characterized by the presence of spontaneous recurrent seizures as a result of sudden and abnormal electrical activity in sp …
Epilepsy is one of the most common neurological disorders in the general population and affects over 50 million people worldwide. Epi …
Microglial Gi-dependent dynamics regulate brain network hyperexcitability.
Merlini M, Rafalski VA, Ma K, Kim KY, Bushong EA, Rios Coronado PE, Yan Z, Mendiola AS, Sozmen EG, Ryu JK, Haberl MG, Madany M, Sampson DN, Petersen MA, Bardehle S, Tognatta R, Dean T Jr, Acevedo RM, Cabriga B, Thomas R, Coughlin SR, Ellisman MH, Palop JJ, Akassoglou K. Merlini M, et al. Nat Neurosci. 2021 Jan;24(1):19-23. doi: 10.1038/s41593-020-00756-7. Epub 2020 Dec 14. Nat Neurosci. 2021. PMID: 33318667 Free PMC article.
Here, we found that G(i)-dependent microglial dynamics prevent neuronal network hyperexcitability. By generating Mg(PTX) mice to genetically inhibit G(i) in microglia, we show that sustained reduction of microglia brain surveillance and directed process motility induced sp …
Here, we found that G(i)-dependent microglial dynamics prevent neuronal network hyperexcitability. By generating Mg(PTX) mice to gene …
In vivo experimental models of epilepsy.
Rubio C, Rubio-Osornio M, Retana-Márquez S, Verónica Custodio ML, Paz C. Rubio C, et al. Cent Nerv Syst Agents Med Chem. 2010 Dec 1;10(4):298-309. doi: 10.2174/187152410793429746. Cent Nerv Syst Agents Med Chem. 2010. PMID: 20868357 Review.
In this review we will focus on how to replicate the different models that have led to the study of partial seizures, as well as generalized seizures and the status epilepticus. The main characteristics that participate in the processes that generat …
In this review we will focus on how to replicate the different models that have led to the study of partial seizures, as well as g …
Antiepileptic drugs: generic versus branded treatments.
Heaney DC, Sander JW. Heaney DC, et al. Lancet Neurol. 2007 May;6(5):465-8. doi: 10.1016/S1474-4422(07)70105-9. Lancet Neurol. 2007. PMID: 17434101 Review.
Antiepileptic drugs (AEDs) are relatively cheap but high volumes of prescriptions mean that substantial drug-budget savings may be possible by switching from innovator brands to cheaper generic drugs. ...Switching to the cheapest generic AED may offer …
Antiepileptic drugs (AEDs) are relatively cheap but high volumes of prescriptions mean that substantial drug-budget savings may be po …
41,610 results
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